Cătălina Bungărdean

Real-world benchmarks for metastatic urothelial carcinoma: a single-center analysis of two standard immunotherapy pathways in Romania

Daniel-Vasile Dulf, Anamaria Larisa Burnar, Doina-Ramona Matei, Patricia-Lorena Dulf et autres

Aim: To establish a real-world benchmark for treatment with the immune checkpoint inhibitors (ICI) and clinical outcomes for patients with metastatic urothelial carcinoma (mUC) by analyzing two distinct, standard-of-care therapeutic sequences at a single Romanian tertiary care center. Methods: We conducted a …

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Risk Stratification Using a Perioperative Nomogram for Predicting the Mortality of Bladder Cancer Patients Undergoing Radical Cystectomy

Daniel-Vasile Dulf, Anamaria Larisa Burnar, Patricia-Lorena Dulf, Cătălina Bungărdean et autres

Background: Perioperative factors significantly impact oncologic outcomes after radical cystectomy (RC) for bladder cancer. This study aimed to identify key perioperative predictors for overall (OS) and progression-free survival (PFS) and to develop a prognostic nomogram for the identification of high-risk patients adapted …

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Lymphovascular Invasion Is a Predictor of Clinical Outcomes in Bladder Cancer Patients Treated with Radical Cystectomy

Daniel-Vasile Dulf, Anamaria Larisa Burnar, Patricia-Lorena Dulf, Raluca Maria Bungărdean et autres

Background/Objectives: Lymphovascular invasion (LVI) has been consistently linked to poor outcomes in patients with bladder cancer (BC), yet its independent prognostic value, especially after adjusting for established pathological features, remains debated. This study aimed to evaluate the prognostic value of LVI in …

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Simultaneous Prostate and Bladder Cancer with Collision Lymph Node Metastasis: A Case Report and Literature Review

Maximilian Buzoianu, Iulia Andraș, Lorin Giurgiu, Claudia Militaru et autres

Synchronous prostatic adenocarcinoma found in patients with muscle-invasive bladder cancer (MIBC) that undergo radical cistoprostatectomy is not uncommon. Nonetheless, the occurrence of collision metastasis, where both prostate cancer and bladder cancer involve the same lymph node, is exceptionally uncommon, with few cases …

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Renal Ewing sarcoma with extensive neuroectodermal differentiation: Case report and literature review

Alexandra Daniela Sava, Tiberiu Bogdan Szekely, Cornelia Togănel, Adela Vacar et autres

Abstract Ewing sarcoma with renal localization is one of the rarest members of the Ewing sarcoma family with less than 200 cases reported in the Medline database. Considering the fact that the majority of data published on the Ewing sarcoma with neuroectodermal …

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How reliable and useful are angiogenesis blood mediators for prostate cancer diagnosis?

Ovidiu Bălăcescu, Nicolae Crişan, Loredana Bălăcescu, Simona Vișan et autres

PURPOSE: To evaluate if a blood panel of genes involved in the modulation of the immune system, angiogenesis and tumor development could be used for prostate cancer detection. METHODS: Gene expression profiling of blood samples was assessed with the human angiogenesis RT² …

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Local staging of prostate cancer with multiparametric-MRI: accuracy and inter-reader agreement

Cristian Popiţa, Anca-Raluca Popiţa, Adina Andrei, Adriana Rusu et autres

Background. The accuracy of prostate cancer local staging at the time of diagnosis directly influences patient prognosis and treatment. Aim. To evaluate the diagnostic performance and interobserver variability of mp-MRI in local staging of prostate cancer, using the histopathologic findings at prostatectomy …

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Leiomyosarcoma of the inferior vena cava. Our experience and a review of the literature

Cristian Bogdan Rusu, Lilian Gorbatâi, Ludovic Szatmari, Rumelia Koren et autres

Leiomyosarcoma (LMS) of the inferior vena cava (IVC) is a rare malignant tumor, accounting for 2% of all LMSs. Less than 400 cases have been reported in literature. Computed tomography (CT) is the most accurate imaging method in assessing the location of …

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CD105 as a tool for assessing microvessel density in renal cell carcinoma

Andreea Cioca, Diana Muntean, Cătălina Bungărdean

BACKGROUND: Angiogenesis plays an essential role in both tumor growth and metastasis. CD105 expression was correlated with prognosis in many tumors, but its value in renal cell carcinoma (RCC) is still questionable. MATERIALS AND METHODS: The aim of this study was to …

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Axillary accessory breast Gland - a case report.

D. N. Chirilă, Teodora Pop, Delia Muntean, Cătălina Bungărdean et autres

MRI-TRUS fusion guided prostate biopsy – initial experience and assessment of the role of contralateral lobe systematic biopsy

Iulia Andraș, Dana Crișan, Emanuel Darius Căta, Attila Tamas-Szora et autres

AIMS: To present our initial experience and results of MRI-TRUS fusion guided prostate biopsy and assess the role of contralateral lobe systematic biopsy. MATERIAL AND METHOD: A number of 119 patients with clinical or biochemical suspicion for prostate cancer (PCa) were included. …

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MRI-TRUS fusion prostate biopsy of PIRADS score 3 lesions

Emanuel Darius Căta, Iulia Andraș, Attila Tamas-Szora, Cosmin Caraiani et autres