Rafael Laskowski

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

Philipp S. Wild, Janine F. Felix, Arne Schillert, Alexander Teumer et autres

BACKGROUND: Understanding the genetic architecture of cardiac structure and function may help to prevent and treat heart disease. This investigation sought to identify common genetic variations associated with inter-individual variability in cardiac structure and function. METHODS: A GWAS meta-analysis of echocardiographic traits …

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Profile of the Immune and Inflammatory Response in Individuals With Prediabetes and Type 2 Diabetes

Vera Großmann, Volker H. Schmitt, Tanja Zeller, Marina Panova‐Noeva et autres

OBJECTIVE: The inflammatory and immune systems are altered in type 2 diabetes. Here, the aim was to profile the immune and inflammatory response in subjects with prediabetes and diabetes in a large population-representative sample. RESEARCH DESIGN AND METHODS: In total, 15,010 individuals …

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Risk Stratification Following Complex PCI: Clinical Versus Anatomical Risk Stratification Including “Post PCI Residual SYNTAX‐Score” as Quantification of Incomplete Revascularization

Thomas Schwietz, Ioakim Spyridopoulos, Steven Pfeiffer, Rafael Laskowski et autres

BACKGROUND: EuroSCORE and completeness of revascularization predicts long-term survival after multivessel PCI (MV-PCI). The SYNTAX-Score has also been proposed to predict clinical outcome. The prognostic impact of these scores to predict long-term survival after PCI has not yet been compared. METHODS AND …

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Abstract 15992: Risk Stratification Following Complex PCI: Anatomic Vs. Clinical Risk Stratification Compared with the “Post PCI Residual Syntax-score” as Quantification of Incomplete Revascularization

Thomas Schwietz, Steven Pfeiffer, Stephan Fichtlscherer, Volker Schächinger et autres

Background: We have previously shown, that clinical risk stratification using the EuroSCORE and completeness of revascularization predicts long-term survival after multivessel PCI (MV-PCI). The SYN...

Prognostic impact of using drug-eluting-stents on outcome and strategy in multivessel PCI: Data from the Frankfurt MV-PCI registry

Thomas Schwietz, Joachim R. Ehrlich, Salvatore De Rosa, Stephan Fichtlscherer et autres

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Impact of Interventional Strategy for Unprotected Left Main Coronary Artery Percutaneous Coronary Intervention on Long-term Survival

Ralf Lehmann, Joachim R. Ehrlich, Salvatore De Rosa, Ioakim Spyridopoulos et autres

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Clinical Research Impact of Interventional Strategy for Unprotected Left Main Coronary Artery Percutaneous Coronary Intervention on Long-term Survival

Ralf Lehmann, Joachim R. Ehrlich, Salvatore De Rosa, Ioakim Spyridopoulos et autres

Background: Percutaneous coronary intervention (PCI) of unprotected left main coronary artery (ULMCA) is feasible. In cases involving the left anterior descending‐left circumflex bifurcation, the optimal interventional strategy remains unclear. Randomized bifurcation trials in the past excluded ULMCA lesions. Methods: A single-centre registry …