Toshimitsu Iinuma

Trigeminal ganglion-trigeminal spinal subnucleus oralis pathway contributes to orofacial neuropathic pain

Yurika Ide, Koichi Iwata, Yoshinori Hayashi, Suzuro Hitomi et autres

ABSTRACT: The aim of this study was to investigate the potential role of the trigeminal ganglion (TG)-trigeminal spinal subnucleus oralis (Vo) pathway in the orofacial neuropathic pain development, using a male rat model with partial ligation of the infraorbital nerve (PNL). Many …

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Association between oral health and nutritional intake among older denture wearers

Takamasa Yoshida, Kensuke Nishio, Y. Yasuda, Shigefumi OKADA et autres

PURPOSE: This study examined the association between oral health and nutritional intake among older denture wearers. METHODS: Oral health parameters were evaluated in 114 denture wearers, including the number of remaining teeth (<20 or ≥20), posterior occlusal support (Eichner classification A1-B3 or …

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Allyl isothiocyanate suppresses the growth and pathogenicity of Candida albicans

Hideki Nishiura, Muneaki Tamura, Rieko Matsuike, Marni E. Cueno et autres

Candida albicans is a fungus that is predominantly detected in the oral cavity and causes opportunistic infections. Among the elderly, a decline in the host's resistance to pathogens due to immunosenescence makes them more susceptible to oral candidiasis, which eventually may progress …

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Ageing‐Related Macrophage Polarisation in the Trigeminal Ganglion Enhances Incisional Intraoral Pain

Kentaro Urata, Tatsuki Oto, Yoshinori Hayashi, Suzuro Hitomi et autres

OBJECTIVE: Although macrophage polarisation in the trigeminal ganglion (TG) is crucial in orofacial pain hypersensitivity, the effect of ageing-related changes and their involvement in intra-oral nociception remains unclear. We assessed the effect of ageing-related macrophage polarisation in TG on intra-oral mechanical pain …

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Author response for "Ageing‐Related Macrophage Polarisation in the Trigeminal Ganglion Enhances Incisional Intraoral Pain"

Kentaro Urata, Tatsuki Oto, Yoshinori Hayashi, Suzuro Hitomi et autres

Relationship between malnutrition according to the global leadership initiative on malnutrition criteria and oral health among community-dwelling elderly aged 85 years and older: a cross-sectional study

Kensuke Nishio, Takamasa Yoshida, Yasumichi Arai, Tomoka Ito et autres

BACKGROUND: A new diagnostic criterion for malnutrition, the Global Leadership Initiative on Malnutrition (GLIM) criteria, has been proposed. Despite a recognized link between malnutrition and oral health, further clarification is needed regarding this association when using the GLIM criteria. This study examined …

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Effect of soft denture liners on complete denture treatments: A systematic review

Yoko Hasegawa, Hajime Minakuchi, Masahiro Nishimura, Kensuke Nishio et autres

PURPOSE: This systematic review examined the effectiveness of soft denture relining (SDR) materials. STUDY SELECTION: A comprehensive search of MEDLINE, Cochrane Library, and ICHUSHI was conducted up to July 26, 2020. Target outcomes were patient satisfaction, oral health-related quality of life (OHRQOL), …

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Diagnostic Study of Mandibular Cortical Index Classification Using Dental Cone-Beam Computed Tomography Findings: A Preliminary Cross-Sectional Study

Keisuke Seki, Tona Yoshino, Shouhei Ogisawa, Yushi Arai et autres

The prevalence of osteoporosis is high, reportedly affecting 200 million people worldwide. A major problem associated with osteoporosis is that femoral fractures cause a decline in general function and loss of independence, greatly reducing patients' quality of life. Notably, osteoporosis is an …

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Diagnostic Study of Mandibular Cortical Index Classification Using Dental Cone-Beam Computed Tomography Findings: A Preliminary Cross-Sectional Study

Keisuke Seki, Tona Yoshino, Shouhei Ogisawa, Yushi Arai et autres

Background and Objectives: The prevalence of osteoporosis is high, reportedly affecting 200 million people worldwide. A major problem associated with osteoporosis is that femoral fractures cause a decline in general function and loss of independence, greatly reducing patients’ quality of life. Notably, …

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Allograft inflammatory factor-1 released from the cerebral microglia affect several organs in the body

Mai Fukasawa, Kensuke Nishio, Daichi Oikawa, Tomoka Itou et autres

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Age-related Changes in Trigeminal Ganglion Macrophages Enhance Orofacial Ectopic Pain After Inferior Alveolar Nerve Injury

Shintaro Fujiwara, Kentaro Urata, Tatsuki Oto, Yoshinori Hayashi et autres

Abstract Background/Aim: The ectopic pain associated with inferior alveolar nerve (IAN) injury has been reported to involve macrophage expression in the trigeminal ganglion (TG). However, the effect of age-related changes on this abnormal pain conditions are still unknown. This study sought to …

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A nested case-control study of factors contributing to the development of medication-related osteonecrosis of the jaw in patients using bone resorption inhibitors in Mishima City

Keisuke Seki, Atsushi Kamimoto, Maki Wada, Toshimitsu Iinuma

PURPOSE: Medication-related osteonecrosis of the jaw (MRONJ) is characterized by necrosis of the jawbone with intraoral bacterial infection and has a significant negative impact on oral health-related quality of life. Risk factors for the onset are unknown, and definitive therapeutic approaches have …

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