Olga Meltem Akay

Evaluation of the frequency, risk factors, and outcomes of splanchnic vein thrombosis in myeloproliferative neoplasms: a retrospective cohort study

Ufuk Demirci, Mehmet Baysal, Elif Aksoy, Metban Mastanzade et autres

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Case Report: When Routine Gynecologic Procedures Unmask a Systemic Bleeding Disorder: Refractory Uterine Hemorrhage Leading to the Diagnosis of AL Amyloidosis

Nur Ilayda Genc, Mehmet Gökhan Gönenli, Soğol Sadri, Toygun Çakmak et autres

Refractory peri-procedural bleeding may be the first manifestation of an occult systemic bleeding disorder. A 46-year-old woman with heavy menstrual bleeding developed severe uterine hemorrhage after endometrial sampling and intrauterine device removal, refractory to conservative treatment and requiring balloon tamponade and uterine …

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A Double Jeopardy: Thrombotic Thrombocytopenic Purpura in Systemic Mastocytosis—A Rare but Lethal Conundrum

Sidar Çöpür, Taner Tan, Efe SEMERCİOĞLU, Sinem Civriz Bozdağ et autres

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Images in Vascular Medicine: Beyond the lesion – recognizing hematologic sequelae of venous malformations

Taner Tan, Ahmet Umur Topçu, Erdem ÇIĞ, Olga Meltem Akay

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A Large Room for Improvement Concerning the Management of Relapsed Refractory Large B-cell Lymphoma in Türkiye: Real-World Outcomes in the Setting Without Access to T-Cell Redirecting Therapies

Umut Yılmaz, Mehmet Sinan Dal, Turgay Ulaş, Elif Birtaş Ateşoğlu et autres

Objectives: Large B-cell lymphoma (LBCL) patients who fail frontline therapy (R/R-LBCL) experience highly unfavorable outcomes.The development of T-cell redirecting therapies is rapidly evolving this outlook.However, costs and infrastructural challenges limit access to such innovative therapies.This study was conducted to document the shortcomings …

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1304eP Toxicity profile and molecular correlates of dose-adjusted EPOCH-R in aggressive B-cell lymphomas: A multicenter analysis from Turkey

Mehmet Mutlu Kıdı, Emre Bayram, Musa Barış Aykan, Nuri Karadurmuş et autres

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Allojenik Kök Hücre Naklinde EASIX’in Prognostik Rolü: Tek Merkezden Retrospektif Bulgular

Taner Tan, Ahmet Umur Topçu, Erdem ÇIĞ, Efe SEMERCİOĞLU et autres

ÖZ Amaç: Endotel Aktivasyon ve Stres İndeksi (EASIX), allojenik hematopoetik kök hücre nakli (allo-HKHN) sonrası gelişen komplikasyonları ve mortaliteyi öngörmede potansiyel bir biyobelirteç olarak tanımlanmıştır.Bu çalışmada, farklı zaman noktalarında hesaplanan EASIX skorlarının mortalite ve nakil ilişkili komplikasyonlarla olan ilişkisi değerlendirilmiştir.Hastalar ve Yöntem: …

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Pancreatic Plasmacytoma Post-Allogeneic-HSCT: Diagnosis by EUS-Guided Biopsy

Taner Tan, Ahmet Umur Topçu, Emre Osmanbaşoğlu, Emrah Alper et autres

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A rare case of Hodgkin lymphoma transformed from follicular lymphoma demonstrating 14;18 translocation

Taner Tan, Ahmet Umur Topçu, Hülya Seymen, Sevgi Işık et autres

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PROGNOSTIC IMPLICATIONS OF HIGH-RISK GENETIC MUTATIONS IN MULTIPLE MYELOMA PATIENTS UNDERGOING SECOND AUTOLOGOUS STEM CELL TRANSPLANT

Taner Tan, Ahmet Umur Topçu, Ümit Üre, Emre Osmanbaşoğlu et autres

Objective High-risk genetic mutations significantly influence prognosis in multiple myeloma. Although autologous Hematopoietic Stem Cell Transplantation (auto-HSCT) is a cornerstone of multiple myeloma treatment, the prognostic impact of genetic abnormalities in patients undergoing a second auto-HSCT warrants further investigation. This study aims …

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Simplified Molecular International Prognostic Index as an eligibility criterion for clinical trials: Analysis of the Turkish Lymphoma Study Group's large B‐cell lymphoma cohort

Umut Yılmaz, Esra Terzi Demirsoy, Fatma Keklik Karadağ, Umur Sevket Hatipoglu et autres

Comparative first-line trials in large B-cell lymphoma (LBCL) have mostly failed over the last decade. Failures were commonly attributed to overestimation of the progression risk for the control arms, bringing the precision of the international prognostic index (IPI) into scrutiny. Simplified molecular …

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664 | SIMPLIFIED MOLECULAR IPI AS ELIGIBILITY CRITERIA FOR CLINICAL TRIALS: ANALYSIS OF THE TURKISH LYMPHOMA STUDY GROUP’S LARGE B‐CELL LYMPHOMA COHORT

Ümit Yılmaz, Esra Terzi Demirsoy, Fatma Keklik Karadağ, Umur Sevket Hatipoglu et autres

patients preferred TTP regimens over FD regimens if it provided a 0.71 percentage-point decrease in grade 3/4 CRS risk, a 12.81 percentage-point decrease in CRS-related hospitalization, a 1.88mo OS increase, or a 2.64 percentage-point increase in the probability of CR at 24 …

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