Accès ouvert
2026
supplementary-materials
OpenAlex
Atish Dipankar Choudhury, Lucia Kwak, Alexander Cheung, Kathryn M. Allaire et autres
Maximum grade adverse events, regardless of attribution. AEs are summarized as n (%) for each maximum grade.
Accès ouvert
2026
supplementary-materials
OpenAlex
Atish Dipankar Choudhury, Lucia Kwak, Alexander Cheung, Kathryn M. Allaire et autres
Proportion of patients who experienced any or given category of symptomatic skeletal events by the treatment arms
Accès ouvert
2026
supplementary-materials
OpenAlex
Atish Dipankar Choudhury, Lucia Kwak, Alexander Cheung, Kathryn M. Allaire et autres
Time to event (months) clinical endpoints by baseline and change in CD4+/FoxP3- (effector) proportion, CD8+ proportion, CD8+ / CD4+FoxP3- (Treg) ratio
Accès ouvert
2026
supplementary-materials
OpenAlex
Atish Dipankar Choudhury, Lucia Kwak, Alexander Cheung, Kathryn M. Allaire et autres
Supplementary File 3
Accès ouvert
2026
supplementary-materials
OpenAlex
Atish Dipankar Choudhury, Lucia Kwak, Alexander Cheung, Kathryn M. Allaire et autres
Summary of genetic findings from targeted sequencing of ctDNA and whole exome sequencing (WES) from bone biopsy specimen.
Accès ouvert
2026
supplementary-materials
OpenAlex
Atish Dipankar Choudhury, Lucia Kwak, Alexander Cheung, Kathryn M. Allaire et autres
Supplementary File 1
Accès ouvert
2026
supplementary-materials
OpenAlex
Atish Dipankar Choudhury, Lucia Kwak, Alexander Cheung, Kathryn M. Allaire et autres
Kaplan-Meier estimates of time to treatment failure (TTF), radiographic progression-free survival (rPFS), and overall survival (OS) by A. baseline CD4+FoxP3- (effector) proportion above (high) vs. below (low) median. B. baseline CD8+ proportion above vs. below median. C. baseline CD8+ / CD4+FoxP3+ (Treg) …
Accès ouvert
2026
supplementary-materials
OpenAlex
Atish Dipankar Choudhury, Lucia Kwak, Alexander Cheung, Kathryn M. Allaire et autres
Radium-223 was administered as 55 kBq/kg q4weeks and pembrolizumab as 200 mg q3weeks. Biopsies were performed pre-treatment and after 8 weeks of treatment.
Accès ouvert
2026
supplementary-materials
OpenAlex
Atish Dipankar Choudhury, Lucia Kwak, Alexander Cheung, Kathryn M. Allaire et autres
Immunofluorescence staining of PD-L1+ CD68 myeloid cells in the bone biopsies. A. RNAscope staining of DAPI (cyan), CD68 (orange), PD-L1 (magenta), Tim3 (green), TIGIT (white) and overlay of bone marrow metastasis. CD68+ cells that co-express PD-L1 are indicated with arrow. Tim3+ cells …
Accès ouvert
2026
supplementary-materials
OpenAlex
Atish Dipankar Choudhury, Lucia Kwak, Alexander Cheung, Kathryn M. Allaire et autres
Summary of biopsy yield
Accès ouvert
2026
supplementary-materials
OpenAlex
Atish Dipankar Choudhury, Lucia Kwak, Alexander Cheung, Kathryn M. Allaire et autres
Swimmer’s plot of treatments received. Number of radium-223 and pembrolizumab doses received are listed to the left and right of the bars, respectively. The brackets “[” and “]” represent the planned break period from radium-223 dosing with “[” representing cycle 3 day …
Accès ouvert
2026
supplementary-materials
OpenAlex
Atish Dipankar Choudhury, Lucia Kwak, Alexander Cheung, Kathryn M. Allaire et autres
Supplementary File 2