Shize Zhang

FDABench: A Benchmark for Data Agents on Analytical Queries over Heterogeneous Data

Ziting Wang, Shize Zhang, Haitao Yuan, Jinwei Zhu et autres

The growing demand for data-driven decision-making has created an urgent need for data agents that can reason over heterogeneous data (databases, documents, web content, images, videos, and audio) to answer complex analytical queries. However, evaluating such agents remains challenging: existing benchmarks often …

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Pharmacokinetic and Pharmacodynamic Evaluation of PZ-2891, an Anti-Alzheimer’s Disease Agonist of PANK2

Ying Chen, Huimin Ma, Shize Zhang, Shimeng Qu et autres

Background/Objectives: Alzheimer’s disease (AD) is a neurodegenerative disorder with a high incidence but limited agents. Herein, PZ-2891 was discovered as a novel anti-AD candidate. Both in vivo and in vitro pharmacodynamic (PD) studies and pharmacokinetic (PK) properties were investigated and illustrated in …

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c-Myc-PANK3-EMT axis regulates the structure and function of intestinal barrier in ulcerative colitis

Shize Zhang, Yuang Chen, Nan Aa, Xu Chen et autres

INTRODUCTION: The repair of structural damage of the intestinal barrier is critical to rescue ulcerative colitis (UC), but there lacks effective targets currently. OBJECTIVES: This study aims to explore mechanisms and identify potential targets for repairing the damaged intestinal barrier involved in …

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Folate Attenuates Ulcerative Colitis via PI3K/AKT/NF-κB/MLCK Axis Inhibition to Restore Intestinal Barrier Integrity

Shize Zhang, Tian Cheng, Yuang Chen, Mengqin Wang et autres

Vitamin homeostasis plays a critical role in inflammatory bowel disease management, yet the protective mechanisms and clinical utility of specific vitamins remain incompletely characterized. Within this context, a two-sample Mendelian randomization analysis leveraging genetic instruments for measuring circulating vitamin levels identified folate …

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Multi-omics analyses identify the modulators COX6A1 and NAL as regulators of silk cocoon formation in Plutella xylostella

Ruichang Niu, Qing‐Hui Zeng, Wenjing Wang, Jia Hu et autres

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Regulation of lipid metabolism in Spodoptera frugiperda by the symbiotic bracovirus of the gregarious parasitoid Cotesia ruficrus

Xian Li, Jun‐Long An, Wenqin Yang, Tong‐Xian Liu et autres

Parasitoids alter host energy homeostasis to create a favorable environment for their own development. However, the mechanisms underlying this process remain largely unexplored, especially for gregarious parasitoids. Cotesia ruficrus, a gregarious endoparasitoid native to China, targets the invasive pest Spodoptera frugiperda (fall …

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The Effects of Six Brassica napus Cultivars on the Life Table Parameters of the Green Peach Aphid Myzus persicae (Sulzer) (Hemiptera: Aphididae)

Mi Tian, Lin-Kui Li, Feng Zhu, Shize Zhang

The contents of glucosinolates and erucic acid clearly vary in Brassica napus seeds, but a few studies still focus on the effects of B. napus cultivars on the life table parameters of Myzus persicae. In this study, the life history parameters of …

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Comparative Study of the Current-Carrying Capacity of XLPE and PP Insulated Single-c ore Power Cables

Xiantao Tao, Hao Gong, Shize Zhang, Kai Deng

In order to compare the current-carrying capacity of single-core polypropylene (PP) cables and cross-linked polyethylene (XLPE) cables under different conductor cross-sectional areas, this paper calculates the current-carrying capacity of single-core cable models at two voltage levels of 35kV and 110kV, using the …

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Design of Low-Cost and High-Accurate 8-bit Logarithmic Floating-Point Arithmetic Circuits

Botao Xiong, Xingqi Shao, Chang Liu, Shize Zhang et autres

Recent studies suggest that the 8-bit floating-point (FP) format plays an important role in the deep learning, where the$E4M3$(4-bit exponent, 3-bit mantissa) is suited for the natural language processing model and the$E3M4$is better on computer vision task. In this brief, the logarithmic …

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FPGA-Friendly Architecture of Processing Elements For Efficient and Accurate Quantized CNNs

Botao Xiong, Shize Zhang, Xintong He, Yuchun Chang

An FPGA-friendly processing element based on the small logarithmic floating-point (SLFP) format is proposed. The proposed processing elements not only support inner product but also perform various nonlinear activation functions (NAF), which consume 674× LUT6s and 7× DSPs and operate at 450MHz …

Effects of temperature, relative humidity, and photoperiod on life history of Cotesia ruficrus (Hymenoptera: Braconidae), an indigenous parasitoid of Spodoptera frugiperda (Lepidoptera: Noctuidae)

Wenqin Yang, Xian Li, Fanxin Meng, Tong‐Xian Liu et autres

The indigenous parasitoid Cotesia ruficrus (Haliday) (Hymenoptera: Braconidae) shows promise as a biological control agent for managing the invasive fall armyworm, Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae) in China. However, the influence of environmental factors on C. ruficrus performance remains poorly understood. …

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Knockout of silk fibroin genes in Plutella xylostella results in decreased fitness and performance

Ruichang Niu, Qing‐Hui Zeng, Wenjing Wang, Yijing Wang et autres

BACKGROUND: The ability of insects to spin silk is crucial for their survival, reproduction, and interactions with the environment. The diamondback moth (DBM), Plutella xylostella, a serious agricultural pest, relies on silk production, which influences its behavior and population dynamics. RESULTS: This …

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