Michael M. Scott

RamanCrystalHunter: a new program and database for processing, analysis and identification of Raman spectra

Maxwell C. Day, Qing Zhang, Fabrizio Nestola, S. Lorenzon et autres

it, ca, us, gb, de, cn, cz, ru (code pays fourni par la source)

Petermegawite, Al6(Se4+O3)3[SiO3(OH)](OH)9⋅10H2O, a New AI-Bearing Selenite Mineral, from the El Dragón Mine, Potosí, Bolivia

Hexiong Yang, Xiangping Gu, Michael M. Scott, Robert A. Jenkins et autres

Abstract A new mineral species, petermegawite, ideally Al6(Se4+O3)3[SiO3(OH)](OH)9⋅10H2O, was discovered at the El Dragón mine, Potosí Department, Bolivia. It occurs as aggregates of bladed or tabular crystals. Associated minerals are Co-bearing krut′aite–penroseite (matrix), chalcomenite, ‘clinochalcomenite’ (not IMA approved), molybdomenite, lepidocrocite, goethite, ahlfeldite, …

us, cn (code pays fourni par la source)

Selective ablation of VIP interneurons in the rodent prefrontal cortex results in increased impulsivity

Jessica A. Hatter, Michael M. Scott

It has been well-established that novelty-seeking and impulsivity are significant risk factors for the development of psychological disorders, including substance use disorder and behavioral addictions. While dysfunction in the prefrontal cortex is at the crux of these disorders, little is known at …

us, gb (code pays fourni par la source)

Contributors

Daniela Accorsi‐Mendonça, David J. Adams, Andrew M. Allen, Marlies Alvarenga et autres

br, au, us, nz, ca, gb (code pays fourni par la source)

Leptin signaling and energy homeostasis

Michael M. Scott, Kevin W. Williams

us (code pays fourni par la source)

Targeting oxidized phospholipids by AAV-based gene therapy in mice with established hepatic steatosis prevents progression to fibrosis

Clint M. Upchurch, Scott Yeudall, Caitlin Pavelec, Dennis Merk et autres

Oxidized phosphatidylcholines (OxPCs) are implicated in chronic tissue damage. Hyperlipidemic LDL-R--deficient mice transgenic for an OxPC-recognizing IgM fragment (scFv-E06) are protected against nonalcoholic fatty liver disease (NAFLD). To examine the effect of OxPC elimination at different stages of NAFLD progression, we used …

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Glucose-sensing glucagon-like peptide-1 receptor neurons in the dorsomedial hypothalamus regulate glucose metabolism

Zhaohuan Huang, Ling Liu, Jian Zhang, Kristie Conde et autres

Glucagon-like peptide-1 (GLP-1) regulates energy homeostasis via activation of the GLP-1 receptors (GLP-1Rs) in the central nervous system. However, the mechanism by which the central GLP-1 signal controls blood glucose levels, especially in different nutrient states, remains unclear. Here, we defined a …

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Virus‐induced Hepatic Expression of an Oxidized Phospholipid‐binding Antibody Fragment Prevents Initiation of Hepatic Steatosis and Progression to Fibrosis

Clint M. Upchurch, Scott Yeudall, Caitlin Pavelec, Mohan C. Manjegowda et autres

Oxidized phospholipids have been implicated in chronic pathologies. It had been shown that hyperlipidemic LDL‐R‐deficient mice transgenic for a single chain fragment of an oxidized phosphatidylcholine (OxPC)‐recognizing IgM E06 (scFv‐E06) were protected from developing non‐alcoholic fatty liver disease (NAFLD). To investigate the …

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Virus-induced hepatic expression of an oxidized phospholipid-binding antibody fragment prevents initiation of steatohepatitis and progression to fibrosis

Clint M. Upchurch, Scott Yeudall, Caitlin Pavelec, Mohan C. Manjegowda et autres

us (code pays fourni par la source)

Hydroxymcglassonite-(K), KSr4Si8O20(OH)·8H2O, the first Sr-bearing member of the apophyllite group, from the Wessels mine, Kalahari Manganese Field, South Africa

Hexiong Yang, Xiangping Gu, Michael M. Scott

Abstract A new mineral species, hydroxymcglassonite-(K), ideally KSr4Si8O20(OH)·8H2O, has been found in the Wessels mine, Kalahari Manganese Field, Northern Cape Province, South Africa. It is granular (<0.05 mm), associated with meieranite, sugilite, aegirine, pectolite, and yuzuxiangite. The mineral is colorless, transparent with …

us, cn (code pays fourni par la source)

DNA Methyltransferase 1 and 3a Expression in the Frontal Cortex Regulates Palatable Food Consumption

Mohan C. Manjegowda, Jonathan Joy-Gaba, Eric R. Wengert, Anusha U. Saga et autres

Abstract DNA methylation is an important regulatory mechanism in the control of neuronal function. Both during development and following exposure to salient stimuli, plasticity in the methylation of cytosine residues leads to a change in neuron excitability that subsequently sculpts animal behavior. …

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Leptin suppresses development of GLP-1 inputs to the paraventricular nucleus of the hypothalamus

Jessica E. Biddinger, Roman M. Lazarenko, Michael M. Scott, Richard B. Simerly

The nucleus of the solitary tract (NTS) is critical for the central integration of signals from visceral organs and contains preproglucagon (PPG) neurons, which express leptin receptors in the mouse and send direct projections to the paraventricular nucleus of the hypothalamus (PVH). …

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