Mahla Sattarzadeh Bardsiri

Therapeutic potential of cinnamaldehyde in melanoma: An in silico and in vitro analysis of stratifin and DNMT expression

Ali Afgar, Reza Vahidi, Mehrnaz Sadat Ravari, Maryam Samareh Salavatipour et autres

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Synergistic Effect of Nanoparticles with Probiotics on Gastrointestinal Regenerative Medicine

Seyedeh Mehrnaz Kouhbananinejad, Alireza Farsinejad, Arman Shahabi, Naghmeh Satarzadeh et autres

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A cellulose-based skin adhesive hydrogel incorporating N-acetyl-seryl-aspartyl-lysyl-proline peptide for enhanced wound healing and scar prevention in rabbit scar ear model in vivo

Zahra Ameri, Arman Shahabi, Mahla Sattarzadeh Bardsiri, Hossein Javedani et autres

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Recent advances and applications of the CRISPR-Cas system in the gene therapy of blood disorders

Saeed Zanganeh, Amir Mohammad Zahedi, Mahla Sattarzadeh Bardsiri, Ali Bazı et autres

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6-Gingerol modulates miRNAs and PODXL gene expression via methyltransferase enzymes in NB4 cells: an in silico and in vitro study

Ali Afgar, Mahdiyeh Ramezani Zadeh Kermani, Athareh Pabarja, Amir Reza Afgar et autres

This investigation delves into the influence of predicted microRNAs on DNA methyltransferases (DNMTs) and the PODXL gene within the NB4 cell line, aiming to elucidate their roles in the pathogenesis of acute myeloid leukemia (AML). A comprehensive methodological framework was adopted to …

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Catechin-Induced changes in PODXL, DNMTs, and miRNA expression in Nalm6 cells: an integrated in silico and in vitro approach

Ali Afgar, Alireza Keyhani, Amirreza Afgar, Mohamad Javad Mirzaei-Parsa et autres

BACKGROUND: This study explored the impact of predicted miRNAs on DNA methyltransferases (DNMTs) and the PODXL gene in Nalm6 cells, revealing the significance of these miRNAs in acute lymphocytic leukemia (ALL). METHODS: A comprehensive approach was adopted, integrating bioinformatic analyses encompassing protein …

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Catechin-induced changes in PODXL, DNMTs, and miRNA expression in NALM6 cells: An integrated in silico and in vitro approach

Ali Afgar, Alireza Keyhani, Amirreza Afgar, Mohamad Javad Mirzaei-Parsa et autres

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Kermanian propolis induces apoptosis through upregulation of Bax/Bcl-2 ratio in acute myeloblastic leukemia cell line (NB4)

Maryam Samareh Salavatipour, Seyedeh Mehrnaz Kouhbananinejad, Mahla Lashkari, Mahla Sattarzadeh Bardsiri et autres

Objective: Propolis is a viscous resinous honeybee-produced substance with numerous medicinal functions; its composition and texture varies according to the geographic location. It is considered to be a promising natural source for the management and prevention of various pathological conditions. Although several …

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Association of IKZF1 and CDKN2A gene polymorphisms with childhood acute lymphoblastic leukemia: a high-resolution melting analysis

Mahla Sattarzadeh Bardsiri, Shahrzad Zehtab, Najibe Karami, Alireza Farsinejad et autres

BACKGROUND: Acute lymphoblastic leukemia is the most prevailing pediatric hematologic malignancy, and various factors such as environmental exposures and genetic variation affect ALL susceptibility and patients outcome. According to genome-wide association studies, several single nucleotide polymorphisms (SNPs) in IKZF1 (rs4132601) and CDKN2A …

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Association of DNA repair genes polymorphisms with childhood acute lymphoblastic leukemia: a high-resolution melting analysis

Shahrzad Zehtab, Mahla Sattarzadeh Bardsiri, Roohollah Mirzaee Khalilabadi, Mohsen Ehsan et autres

OBJECTIVE: Acute lymphoblastic leukemia (ALL) is one of the most common cancers in children for which the exact pathogenesis is not yet known. Single-nucleotide variants (SNVs) in different DNA repair genes are reported to be associated with ALL risk. This study aimed …

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Ubiquitous convalescent plasma: An artificial universal plasma for COVID-19 patients

Mahla Sattarzadeh Bardsiri, Seyedeh Mehrnaz Kouhbananinejad, Reza Vahidi, Saeed Soleimany et autres

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Green Synthesis of Stable Silver Nanoparticles Using Teucrium polium Extract: In-vitro Anticancer Activity on NALM-6

Seyed Mohammad Amini, Maryam Samareh Salavatipour, Reza Vahidi, Seyedeh Mehrnaz Kouhbananinejad et autres

Abstract: The therapeutic effect of silver nanoparticles on leukaemia cancerous cells has been demonstrated in several studies. However, most of these nanoparticles are toxic to normal cells as well as cancerous cells. In the present study, green chemistry has been applied for …

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