Accès ouvert
2026
article
OpenAlex
Nicholas A. Marston, Erin A. Bohula, Ajay Bhatia, Gaetano M. De Ferrari et autres
Importance: Intensive lowering of low-density lipoprotein cholesterol (LDL-C) levels with PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors for cardiovascular event reduction has largely been reserved for patients with significant atherosclerosis. Objective: To investigate whether evolocumab could prevent a first major cardiovascular event …
us, tr, it, ca, br, gb, au, es, de
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Accès ouvert
2025
article
OpenAlex
Annelot J. L. Peijster, Floris J Heinen, Sabrine Douiyeb, Michelle D. van der Stoel et autres
BACKGROUND: Despite advancements in diagnostics and treatment strategies, infective endocarditis continues to carry a substantial morbidity and mortality risk. In addition, the field of infective endocarditis contains many gaps in evidence, as international guidelines are predominantly based on low-level evidence. To improve …
nl, ie
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Accès ouvert
2025
article
OpenAlex
Faı̈ez Zannad, Christopher M. O’Connor, Javed Butler, Ciaran J. McMullan et autres
BACKGROUND: Following completion of the VICTORIA trial, vericiguat was approved for the treatment of worsening heart failure with reduced ejection fraction (HFrEF) and received a class IIb recommendation in European and North American guidelines. The subsequent VICTOR trial evaluated the use of …
fr, us, ch, ca, sg, pl, it, de, nl
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Accès ouvert
2025
article
OpenAlex
Viktoria Wieske, Mario Walther, Mahmoud Mohamed, Benjamin Weickert et autres
BACKGROUND: Combining pretest probability (PTP) with computed tomography angiography (CTA) for diagnosing obstructive coronary artery disease (CAD) has not yet been determined. OBJECTIVES: The purpose of this study was to evaluate the accuracy of PTP calculation alone and with CTA for diagnosing …
de, fr, it, ch, us, be, ir, dk, nl, jp, gb, fi, il, no, br, tw, pt, cn, ca, sg, ie
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Accès ouvert
2024
article
OpenAlex
Gerlinde van der Maten, Xavier Pouwels, Matthijs F.L. Meijs, Clemens von Birgelen et autres
BACKGROUND: The multicenter ATTEST study recently assessed 1084 patients with ischemic stroke or transient ischemic attack (TIA) of undetermined cause and found that routine transthoracic echocardiography (TTE) detects abnormalities with treatment implications (i.e., major cardiac sources of embolism) in only 1 % …
nl
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Accès ouvert
2024
review
OpenAlex
Peter Schlattmann, Viktoria Wieske, Keno K. Bressem, Theresa Götz et autres
AIM: To determine the effectiveness of functional stress testing and computed tomography angiography (CTA) for diagnosis of obstructive coronary artery disease (CAD). METHODS AND RESULTS: Two-thousand nine-hundred twenty symptomatic stable chest pain patients were included in the international Collaborative Meta-Analysis of Cardiac …
de, it, ch, be, ir, nl, jp, dk, gb, fi, il, no, tw, fr, ca
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Accès ouvert
2024
article
OpenAlex
Kausik K. Ray, Carlos Aguíar, Marcello Arca, Derek Connolly et autres
AIMS: To assess whether implementation of the 2019 European Society of Cardiology (ESC)/European Atherosclerosis Society (EAS) dyslipidaemia guidelines observed between 2020 and 2021 improved between 2021 and 2022 in the SANTORINI study. METHODS AND RESULTS: Patients with high or very high cardiovascular …
gb, pt, it, fr, se, de, ch, be, fi, at, nl, nz
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Accès ouvert
2023
article
OpenAlex
Gerlinde van der Maten, Matthijs F.L. Meijs, Jorik R. Timmer, Paul J.A.M. Brouwers et autres
BACKGROUND: Guidelines recommend routine transthoracic echocardiography (TTE) after ischaemic stroke or transient ischaemic attack of undetermined cause; yet, only limited scientific evidence exists. Therefore, we aimed to determine in these patients the prevalence of TTE-detected major cardiac sources of embolism (CSE), which …
nl
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Accès ouvert
2023
review
OpenAlex
Mahmoud Mohamed, Maria Bosserdt, Viktoria Wieske, B. Dubourg et autres
OBJECTIVES: Coronary computed tomography angiography (CCTA) has higher diagnostic accuracy than coronary artery calcium (CAC) score for detecting obstructive coronary artery disease (CAD) in patients with stable chest pain, while the added diagnostic value of combining CCTA with CAC is unknown. We …
de, fr, ch, us, ir, dk, nl, fi, no, tw, pt, it, cn, ca, gb
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Accès ouvert
2023
article
OpenAlex
Gerlinde van der Maten, Matthijs F.L. Meijs, Job van der Palen, Paul J.A.M. Brouwers et autres
OBJECTIVES: Guidelines advise cardiac rhythm monitoring for 3 up to 30 days for detecting atrial fibrillation (AF) in patients with ischemic stroke of undetermined cause. However, the optimal monitoring duration is unknown. We aimed to determine the AF detection rate during 7-day …
nl
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Accès ouvert
2022
erratum
OpenAlex
Viktoria Wieske, Mario Walther, B. Dubourg, Hatem Alkadhi et autres
Objectives There is conflicting evidence about the comparative diagnostic accuracy of the Agatston score versus computed tomography angiography (CTA) in patients with suspected obstructive coronary artery disease (CAD).Purpose To determine whether CTA is superior to the Agatston score in the diagnosis of …
de, fr, ch, dk, nl, tw, ir, no, it, cn, us, fi, pt, ca
(code pays fourni par la source)
Accès ouvert
2022
review
OpenAlex
Viktoria Wieske, Mario Walther, B. Dubourg, Hatem Alkadhi et autres
OBJECTIVES: There is conflicting evidence about the comparative diagnostic accuracy of the Agatston score versus computed tomography angiography (CTA) in patients with suspected obstructive coronary artery disease (CAD). PURPOSE: To determine whether CTA is superior to the Agatston score in the diagnosis …
de, fr, ch, dk, nl, tw, ir, no, it, cn, us, fi, pt, ca
(code pays fourni par la source)