Louise E. Wilkins-Haug

Severe Early‐Onset Fetal Growth Restriction: The Yield of Antenatal and Postnatal Genetic Testing

Matthew H. Mossayebi, Sophie Adams, Megan E. Bunnell, Stephanie H. Guseh et autres

OBJECTIVES: We evaluated the diagnostic yield of karyotype (KT) and chromosomal microarray (CMA) with isolated severe FGR diagnosed before 32 weeks' gestation. Exome and genome sequencing (ES/GS) level data were available in a subset of this population. METHOD: We performed a retrospective …

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Fetal Vein of Galen Malformation—Reply

Darren B. Orbach, Alireza Abdollah Shamshirsaz, Louise E. Wilkins-Haug

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Two Sides of One Circulation

Christina Ronai, Louise E. Wilkins-Haug

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Highlights of the 28th ISPD Annual Conference, Hosted in Boston and Themed “Envisioning Global Fetal–Maternal Genomics and the Paths to Treatment”

Teresa N. Sparks, Louise E. Wilkins-Haug

The authors declare no conflicts of interest. Data sharing not applicable to this article as no datasets were generated or analyzed during the current study.

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In Utero Embolization for Fetal Vein of Galen Malformation

Darren B. Orbach, Alireza Abdollah Shamshirsaz, Louise E. Wilkins-Haug, Stephanie H. Guseh et autres

Importance: Vein of Galen malformation (VOGM) is the most common congenital cerebrovascular anomaly. Fetuses with VOGM and wide mediolateral falcine sinus diameters are at high risk for mortality, brain injury, and neurodevelopmental delay. In utero embolization may improve survival and outcomes. Objective: …

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538 Placental dysfunction and congenital heart disease: investigating the placenta-heart axis

NN Lanners, S Morton, S. Blanco, Sara Mansoorshahi et autres

OBJECTIVE: Concurrent development of the placenta and heart during early gestation suggests a shared biological basis for the co-occurrence of abnormal placentation and congenital heart disease (CHD). This study investigated the association between placental vascular pathology and CHD type. METHODS: A retrospective …

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Routine Prenatal cfDNA Screening for Autosomal Dominant Single-Gene Conditions

Sophie Adams, Olivia Maher Trocki, Christina J. Miller, Courtney Studwell et autres

BACKGROUND: Genetic screening has advanced from prenatal cell-free DNA (cfDNA) screening for aneuploidies (cfDNA-ANP) to single-gene disorders (cfDNA-SGD). Clinical validation studies have been promising in pregnancies with anomalies but are limited in the general population. METHODS: Chart review and laboratory data identified …

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Maternal Vascular Malperfusion and Anatomic Cord Abnormalities Are Prevalent in Pregnancies With Fetal Congenital Heart Disease

Chrystalle Katte Carreon, Christina Ronai, Wayne Tworetzky, Sarah U. Morton et autres

OBJECTIVE: Impairments in the maternal-fetal environment are associated with adverse postnatal outcomes among infants with congenital heart disease. Therefore, we sought to investigate placental anomalies as they related to various forms of fetal congenital heart disease (FCHD). METHODS: We reviewed the placental …

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The bright future of fetal cardiology

Lindsay R. Freud, Lynn L. Simpson, Louise E. Wilkins-Haug

The authors declare no conflicts of interest. Data sharing is not applicable to this article as no new data were created or analyzed in this study.

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The patient experience of a postpartum readmission for hypertension: a qualitative study

Radhika Viswanathan, Sarah E Little, Louise E. Wilkins-Haug, Ellen W. Seely et autres

BACKGROUND: Hypertensive disorders of pregnancy (HDP) are the most common cause of postpartum readmission. Prior research led to clinical guidelines for postpartum management; however, the patient experience is often missing from this work. The objective of this study is to understand the …

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Technical Success and Serious Adverse Events for Fetal Aortic Valvuloplasty in a Large 20-Year Cohort

Ryan M. Callahan, Kevin G. Friedman, Wayne Tworetzky, Jesse J. Esch et autres

FAV is offered to fetuses with severe aortic valve stenosis and evolving hypoplastic left heart syndrome. An inferential analysis of TS and SAE in a large series has not been reported. The purpose of this study was to determine factors associated with …

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High-Resolution and Noninvasive Fetal Exome Screening

Harrison Brand, Christopher W. Whelan, Michael Duyzend, John Lemanski et autres

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