M Vatve

BI21 The development of diffuse extragenital lichen sclerosus in a patient on palbociclib and fulvestrant for metastatic breast cancer

Sarah Louise Johnston, M Vatve, Lianne Thomas

Abstract A 59-year-old woman with skin phototype VI was commenced on palbociclib (cyclin-dependent kinase 4/6 inhibitor) and fulvestrant (oestrogen receptor antagonist) as chemotherapy agents for metastatic breast cancer. Two months later, she developed a new widespread rash. Past medical history included atopic …

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Doxycycline versus prednisolone as an initial treatment strategy for bullous pemphigoid: a pragmatic, non-inferiority, randomised controlled trial

Hywel C Williams, Fenella Wojnarowska, Gudula Kirtschig, James M. Mason et autres

BACKGROUND: Bullous pemphigoid is a blistering skin disorder with increased mortality. We tested whether a strategy of starting treatment with doxycycline gives acceptable short-term blister control while conferring long-term safety advantages over starting treatment with oral corticosteroids. METHODS: We did a pragmatic, …

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Clinical outcomes and response of patients applying topical therapy for pyoderma gangrenosum: A prospective cohort study

Kim Suzanne Thomas, Kim S. Thomas, Anthony David Ormerod, Fiona E. Craig et autres

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Evaluation of patch test in identification of causative agent in drug rashes due to antiepileptics.

M Vatve, Vikas Kumar Sharma, Inder M. S. Sawhney, B Kumar

Patch test was evaluated for the identification of causative agent in cutaneous eruptions due to antiepileptics. Patch tests were carried out in twenty patients and ten controls with carbamazepine, phenytoin sodium, phenobarbitone and sodium valproate. Sodium valproate was found tobe irritant in …

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A case of mid-dermal elastolysis after narrowband ultraviolet B phototherapy

M Vatve, Richard Morton, David Bilsland

Conflict of interest: none declared. Mid‐dermal elastolysis (MDE) is a rare disorder first described in 1977, which usually presents clinically with circumscribed areas of fine skin wrinkling and histologically with a band of elastin loss in the mid dermis.1 The pathogenesis of …

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Clinical spectrum of drug rashes due to antiepileptics.

Vikas Kumar Sharma, M Vatve, Inder M. S. Sawhney, B Kumar

Clinical profile of 105 patients with cutaneous drug eruption due to antiepileptic drugs was studied between 1992-1996. Maculopapular rash was the most common presentation though significant number of patients (29.5%) had serious rashes like Stevens Johnson syndrome (SJS) and toxic epidermal necrosis …

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Blue Rubber Bleb Nevus Syndrome: A Cause for Recurrent Episodic Severe Anemia

J. S. Goraya, Ram Kumar Marwaha, M Vatve, Amita Trehan

A 7-year-old boy had several episodes of severe anemia, requiring hospitalizations and blood transfusions. Skin hemangiomas characteristic of blue rubber bleb nevus syndrome were present since infancy, but were not recognized as being indicative of simultaneous existence of bowel hemangiomas, resulting in …

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Rifampicin-induced urticaria in leprosy

Vinod Kumar Sharma, Inderjeet Kaur, M Vatve, Bhushan Kumar

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