Lijie Huang

Assessment of Cerebral Microvascular Development in Preterm Neonates Using Ultrafast Power Doppler Imaging

Lijie Huang, Jinfang Yuan, Xingyue Wei, Hou Xf et autres

Purpose: The incidence of preterm birth is reported as more than 10% in 2020 all over the world, and the disability and mortality rate are high due to incomplete development. The microvascular developments of neonates with different gestational ages (GAs) are unknown, …

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Contrast-Free Ultrasound Microvascular Imaging via Radiality and Similarity Weighting

Jingyi Yin, Jingke Zhang, Lijie Huang, U‐Wai Lok et autres

Microvascular imaging has advanced significantly with ultrafast data acquisition and improved clutter filtering, enhancing the sensitivity of power Doppler imaging to small vessels. However, the image quality remains limited by spatial resolution and elevated background noise, both of which impede visualization and …

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Fast 3-D Ultrasound Localization Microscopy via Projection-Based Processing Framework

Jingke Zhang, Jingyi Yin, U‐Wai Lok, Lijie Huang et autres

Three-dimensional ultrasound localization microscopy (ULM) enables comprehensive visualization of the vasculature, thereby improving diagnostic reliability. Nevertheless, its clinical translation remains challenging, as the exponential growth in voxel count for full 3D reconstruction imposes heavy computational demands and extensive post-processing time. In this …

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Self-supervised deep learning for denoising in ultrasound microvascular imaging

Lijie Huang, Jingyi Yin, Jingke Zhang, U‐Wai Lok et autres

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Super-Resolution Posterior Ocular Microvascular Imaging Using 3-D Ultrasound Localization Microscopy With a 32X32 Matrix Array

Junhang Zhang, U‐Wai Lok, Jingke Zhang, Chengwu Huang et autres

The purpose of this study is to enable in-vivo three-dimensional (3-D) ultrasound localization microscopy (ULM) of posterior ocular microvasculature using a 256-channel system and a 1024-element matrix array, and to overcome limitations of restricted transmit angles, sound speed mismatch caused by the …

Effective Hyper-clutter Artifacts Suppression for Ultrafast Ultrasound Doppler Imaging.

Lijie Huang, Jingyi Yin, Jingke Zhang, U‐Wai Lok et autres

OBJECTIVE: Hyper-clutter artifacts (HCA), arising from strong tissue reflections or physiological motion, present persistent challenges in ultrafast ultrasound Doppler imaging, often obscuring surrounding small vessel flow signals, especially in fascial regions such as the renal capsule. This study proposes U-profile-based decluttering (UPBD), …

A Rapid In Vitro Endothelialization Approach for Small‐Diameter Vascular Grafts via Covalent Reaction

Ye Wan, Songdi Wang, Haowen Li, Xi Sun et autres

Abstract Small‐diameter vascular grafts are prone to thrombosis and stenosis mainly due to inadequate endothelialization. The current in vitro endothelial cells (ECs) seeding methods are time‐consuming and insufficient to resist blood flow erosion, which limited the application of pre‐endothelialized grafts. Herein, human …

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Enhanced Contrast-Free in vivo 3D Ultrasound Microvessel Imaging using Hadamard Multipulse Diverging Wave Transmission and Denoising with a 32×32 Matrix array

U‐Wai Lok, Chengwu Huang, Jingke Zhang, Ryan M. DeRuiter et autres

Two-dimensional (2D) Ultrasound Microvessel Imaging (UMI) is a contrast-free technique that enables the visualization of slow blood flow in small vessels by combining high frame-rate imaging with advanced tissue clutter filtering. While 2D UMI has been successfully applied in various clinical and …

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A nomogram based on the TyG index for the prediction of lower-limb venous thrombosis in patients with intracerebral hemorrhage

Lijie Huang, Fengda Li

Venous thrombosis is a serious complication that adversely impacts the prognosis of patients with intracerebral hemorrhage (ICH) and even threatens their lives. Triglyceride glucose product (TyG) index is closely related to the pathophysiological process of cerebral hemorrhage and venous thrombosis. A total …

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Tissue Clutter Filtering Methods in Ultrasound Localization Microscopy Based on Complex-Valued Networks and Knowledge Distillation

Wenzhao Han, Wenjun Zhou, Lijie Huang, Jianwen Luo et autres

Ultrasound localization microscopy (ULM) is a blood flow imaging technique that utilizes micrometer-sized microbubbles (MBs) as contrast agents to achieve high-resolution microvessel reconstruction through precise localization and tracking of MBs. The accuracy of MB localization is critical for producing high-quality images, which …

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Bedside cerebral microvascular imaging of patients with disorders of consciousness: a feasibility study

Qianqian Ge, Lijie Huang, Qiang Fu, Shuai Han et autres

Background: Efficient bedside neurofunctional monitoring is crucial for managing disorders of consciousness (DoC). Ultrafast Power Doppler Imaging (uPDI) outperforms traditional Ultrasound in bedside for assessing the microcirculatory system. However, intracranial blood flow imaging traditionally faces limitations due to the skull's impedance. This …

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Ultrafast Online Clutter Filtering for Ultrasound Microvascular Imaging

Yinran Chen, Baohui Fang, Huaying Li, Lijie Huang et autres

Spatiotemporal clutter filtering via robust principal component analysis (rPCA) has been widely used in ultrasound microvascular imaging. However, the performance of the rPCA clutter filtering highly relies on low-rank modeling for tissue signals and sparse modeling for blood flow signals. Moreover, current …

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