Fengting Lv

Panchromatic Polymer Dot–Bacteria Biohybrid Systems for Photosynthetic CO 2 Reduction into Acetic Acid

Weijian Chen, Mariia V. Pavliuk, Wen Bing Yu, Yiming Huang et autres

Enabling the nonphotosynthetic bacterium Moorella thermoacetica (M. thermoacetica) to form a photosynthetic biohybrid system could transform carbon dioxide (CO2) into value-added products. However, to ensure an efficient, mechanistic electron-transfer pathway to microbial catalysts, a pivotal nanoplatform that involves multicomponent composite systems for …

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Electrochemical Oxidation of Water Through Conducting Polymer for Hydroxyl Radical Generation at Ultra‐Low Voltage

Shengpeng Xia, Haitao Yuan, Wen Yu, Yuhsuan Lee et autres

ABSTRACT Although conducting polymers (CPs) have catalyzed the development of advanced optoelectronic devices, their performance in aqueous environments remains largely underexplored due to the quenching of electron/hole by water molecules. In this study, we present an unconventional electrochemical strategy to achieve unexpected …

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pH-Responsive Supramolecular System for Activation of Cellular Calcium Channels

Gang Song, Mingyu Kenneth Li, Qi Shen, Yiming Huang et autres

Ion channels play essential roles in cellular signaling, yet achieving precise, on-demand activation within the tumor microenvironment (TME) remains challenging. In this study, we develop a pH-responsive supramolecular assembly composed of a water-soluble cationic oligophenylenevinylene derivative (OPV-hex) and an acid-cleavable molecule (DMMA). …

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Conjugated polymer nanoparticles (CPNs)-based optogenetic platform reprogramming the tumor microenvironment of MSS colorectal cancer

Miaomiao Gou, Xuancheng Fu, Gang Yong Song, Chang Liu et autres

Illustration of the remote control cancer immunotherapy mediated by photothermal conjugated polymer nanoparticles (CPNs) as showed localized, heat-triggered expression of IFN-γ and IL-2 reshape the TME by promoting macrophage repolarization and T cell proliferation. • This study demonstrated that the near-infrared (NIR)-responsive …

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The Role of Conducting Polymers in Advancing Organoid Technology: A Perspective on Construction Assessment, Monitoring Devices, and Novel Bioregulation Strategies

Hongrui Lin, HeJun WangJia Song, Yafeng Zou, Fengting Lv et autres

Conducting polymers (CPs) exhibit unique optoelectronic and bioactive properties, enabling the precise monitoring and modulation of complex physiological processes within organoid systems. This review highlights recent advances in CP-enhanced organoid technology, focusing on their roles in evaluating organoid construction, constructing device platforms …

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Machine Learning-Guided Decoding Bioelectronic Signals of Photosynthetic Cyanobacterial Cells by Conducting Polymers

Miaomiao Zhang, Junjie Cheng, Wen Bing Yu, Zenghao Wang et autres

Rapid and reliable communication with photosynthetic organisms is essential for monitoring their physiological states, which would reflect their endogenous bioelectric signals. However, these signals are inherently weak and challenging to detect due to the low efficiency of bioelectronic generation and transmission. In …

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Supramolecularly gated enzymes: On-demand activity switching via host-guest competition for precision tumor therapy

Huijuan Yang, Xiangrui Shi, Ziyi Li, Lan Yang et autres

Dynamic control over enzyme function has been of great interest in the field of enzyme engineering and disease treatment, however, achieving on-demand regulation of native enzymes in living systems remains challenging due to the complexity of cellular environments and the lack of …

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Synthesis of Conductive Polymers in Living Plants Using an Enzyme-Assisted Polymerization Strategy for Sensing and Energy Storage

Miaomiao Zhang, Shengpeng Xia, Rui Li, Yiming Huang et autres

Living plants provide sustainable and adaptive systems, and enabling them with in vivo electroactivity could open promising avenues for green sensing and energy technologies. However, integrating conductive polymers into living tissues without harming the viability remains challenging. Here, we develop a living …

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A New Strategy for Controlled In Situ Release of IL‐2 from Tumor Spheroids Using a NIR‐II Light‐Mediated Optogenetic Manipulation System

Hongrui Lin, Junjie Cheng, Rui Li, Chuanwei Zhu et autres

Interleukin-2 (IL-2) is a clinically significant immunotherapeutic agent; its short half-life and poor targeting specificity in vivo have made controlled in situ release an important area of investigation. However, traditional 2D cell experiments and animal studies cannot fully replicate the real environment …

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Chemical Reactions in Cellular Microenvironments Directed by Conjugated Polymers Toward Biomedical Advances

Shuaian Shi, Hongrui Lin, Junjie Cheng, Yan Jun Zhao et autres

Conjugated polymers exhibit unique structural and optoelectronic properties, enabling precise modulation of chemical reactions within cellular microenvironments. This review highlights recent advances in CP-directed biomedical strategies, focusing on their roles in light-driven biophotocatalysis, photodynamic and photothermal therapies, and precision cellular regulation. By …

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Chemical Reactions in Cellular Microenvironments Directed by Conjugated Polymers Toward Biomedical Advances

Shuaian Shi, Hongrui Lin, Junjie Cheng, Yan Zhao et autres

Abstract Conjugated polymers exhibit unique structural and optoelectronic properties, enabling precise modulation of chemical reactions within cellular microenvironments. This review highlights recent advances in CP‐directed biomedical strategies, focusing on their roles in light‐driven biophotocatalysis, photodynamic and photothermal therapies, and precision cellular regulation. …

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Ion-equilibrated OECT inverters for neural-compatible ring oscillators

Xiangyuan Mei, Xiao Yu, Chaoyi Yan, Lingxuan Jia et autres

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