Ellen B. Cook

675. The Fidaxomicin Cascade: Analysis of Success Rates and Barriers of Fidaxomicin Discharge Prescriptions for Inpatients Diagnosed with Clostridiodes Difficile

Ellen B. Cook, Jigar Mehta, Alexis L Blecher, Matthew Lee

Abstract Background Current IDSA guidelines prefer Fidaxomicin for initial and first recurrent Clostridiodes difficile (C. difficile) infection. A barrier to increasing Fidaxomicin usage has been the medication’s potential high co-pay. The objective of this study was to evaluate the discharge success rate …

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Severe Skin Infections Due to Serratia marcescens

Kinjal P. Gadhiya, John A. Goldman, Panupong Hansrivijit, Divya Balchander et autres

Abstract Serratia marcescens is a gram-negative bacilli belonging to the Enterobacteriaceae family associated with septic shock and high mortality. It rarely presents as soft tissue infections. Here, we describe a first and rare case report as well as a review of literature …

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Allergic and Immunologic Diseases of the Eye

Neal P. Barney, Ellen B. Cook, James L. Stahl

Contributors

Seema Sharma Aceves, Ian Michael Adcock, Newton Franklin Adkinson, Cezmi A. Akdiş et autres

PGD 2 promotes eosinophil chemotaxis, degranulation and Syk phosphorylation

Ellen B. Cook, James L. Stahl, Elizabeth A. Schwantes, Sameer K. Mathur et autres

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IL-5, GM-CSF and FMLP-stimulated eosinophil degranulation is inhibited by Olopatadine, but not other drugs in the same class

Ellen B. Cook, James L. Stahl, Elizabeth A. Schwantes, Neal P. Barney et autres

IL-5, GM-CSF, and FMLP-Stimulated Eosinophil Degranulation Is Inhibited by Olopatadine, but Not Other Drugs in the Same Class

Ellen B. Cook, James L. Stahl, Elizabeth A. Schwantes, Sameer K. Mathur et autres

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IL-3 and TNFα increase Thymic Stromal Lymphopoietin Receptor (TSLPR) expression on eosinophils and enhance TSLP-stimulated degranulation

Ellen B. Cook, James L. Stahl, Elizabeth A. Schwantes, Kristen E Fox et autres

BACKGROUND: Thymic stromal lymphopoietin (TSLP) and eosinophils are prominent components of allergic inflammation. Therefore, we sought to determine whether TSLP could activate eosinophils, focusing on measuring the regulation of TSLPR expression on eosinophils and degranulation in response to TSLP, as well as …

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Human eosinophils release IL ‐1ß and increase expression of IL ‐17A in activated CD 4+ T lymphocytes

Stephane J. Esnault, ELIZABETH A. BECKY KELLY, Lauren M. Nettenstrom, Ellen B. Cook et autres

BACKGROUND: Differentiation and activation of CD4(+) T cells is controlled by various cytokines produced by innate immune cells. We have shown that eosinophils (EOS) have the potential to influence Th1 and Th2 cytokine generation by CD4(+) cells, but their influence on IL-17A …

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Modulation of Eosinophil Responsiveness to TSLP-Mediated Degranulation by Conjunctival Epithelial Cells and Allergic Cytokines

Ellen B. Cook, James L. Stahl, Elizabeth A. Schwantes, Sameer A. Mathur et autres

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Modulation of Eosinophil Responsiveness to TSLP-Mediated Degranulation

Ellen B. Cook, James L. Stahl, Elizabeth A. Schwantes, Neal P. Barney et autres

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TSLP enhances barrier function in human conjunctival epithelial cells

Ellen B. Cook, James L. Stahl, Elizabeth A. Schwantes, Neal P. Barney et autres