An orally available PfPKG inhibitor blocks Plasmodium’s infection of the liver
Hanna Dhiyebi, Aminata Mbaye, Anusha Thaniana, John Gilleran et autres
0 citationsPLoS Pathogens
Jacques Y. Roberge
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59Publications signalées
942Citations signalées
2Affiliations récentes
Institutions déclarées
Domaines associés
Carbohydrate Chemistry and SynthesisGlycosylation and Glycoproteins ResearchChemical Synthesis and AnalysisTGF-β signaling in diseasesAsymmetric Synthesis and Catalysis
Publications récentes
Bone morphogenetic protein receptor 2 signaling mediates mitochondrial Ca2+ transport through its regulation of TAK1 splice variant
Ashley Toussaint, Manohar Singh, Hellen Chiou, Guoqiang Wang et autres
0 citationsCell Communication and Signaling
A FtsZ inhibitor-acinetobactin conjugate with enhanced cellular uptake in Acinetobacter baumannii acts synergistically in combination with PBP3-targeting antibiotics
Eric J. Bryan, Zoltán Székely, Yuxuan Wang, Huizhou Fan et autres
4 citationsPLoS ONE
An orally available PfPKG inhibitor blocks sporozoite infection of the liver
Hanna Dhiyebi, Aminata Mbaye, Anusha Thaniana, John Gilleran et autres
0 citationsbioRxiv (Cold Spring Harbor Laboratory)
Binding of small molecules at the P-stalk site of ricin A subunit trigger conformational changes that extend into the active site
J. McLaughlin, M. Rudolph, Arkajyoti Dutta, Xiaoping Li et autres
1 citationJournal of Biological Chemistry
BMP receptor 2 inhibition regulates mitochondrial bioenergetics to induce synergistic cell death with BCL-2 inhibitors in leukemia and NSLC cells
Ashley Toussaint, Manohar Singh, Guoquiang Wang, Monica Driscoll et autres
0 citationsResearch Square
Correction to “Structure–Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials”
John Gilleran, Kutub Ashraf, Melvin Delvillar, Tyler Eck et autres
1 citationJournal of Medicinal Chemistry
Fragment Screening to Identify Inhibitors Targeting Ribosome Binding of Shiga Toxin 2
M. Rudolph, Anastasiia M. Tsymbal, Arkajyoti Dutta, Simon A. Davis et autres
2 citationsACS Infectious Diseases
A FtsZ Inhibitor That Can Utilize Siderophore-Ferric Iron Uptake Transporter Systems for Activity against Gram-Negative Bacterial Pathogens
Eric J. Bryan, Qiao Qi, Yuxuan Wang, Jacques Y. Roberge et autres
5 citationsAntibiotics
Structure–Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials
John Gilleran, Kutub Ashraf, Melvin Delvillar, Tyler Eck et autres
14 citationsJournal of Medicinal Chemistry
Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin
M. Rudolph, Arkajyoti Dutta, Anastasiia M. Tsymbal, J. McLaughlin et autres
6 citationsBioorganic & Medicinal Chemistry
Acylpyrazoline-Based Third-Generation Selective Antichlamydial Compounds with Enhanced Potency
Bin Lü, Qiao Qi, Elizabeth R. Park, Yuxuan Wang et autres
0 citationsACS Omega
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