Joseph Kapelushnik

FTIR spectroscopy of peripheral blood mononuclear cells and machine learning: Spectral biomarkers for bacteremia, focal bacterial, and viral infections

Uraib Sharaha, Yotam D. Eshel, Dima Bykhovsky, Mishel Chernyak et autres

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Rapid Diagnosis of Bacteremia in Febrile Pediatric Oncology Patients via Host-Response Infrared Spectroscopy of Blood and Machine Learning

Yotam D. Eshel, Uraib Sharaha, Dima Bykhovsky, Mishel Chernyak et autres

Bacteremia is a life-threatening complication and a leading cause of sepsis and septic shock in patients. Conventional diagnostic methods, such as blood culture, remain the clinical gold standard but require 24-72 h, often necessitating the empirical use of broad-spectrum antibiotics, which significantly …

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Increased Prevalence of Thromboembolic Events in Patients with Congenital Dyserythropoietic Anemia Type I

Mahdi Asleh, Aya Khalaila, Y. Eshel, Kayed Al-Athamen et autres

Introduction: Congenital dyserythropoietic anemia type I (CDA-I) is a rare disorder of erythropoiesis. All CDA-I patients are expected to have iron overload and chronic hemolysis. Patients with severe anemia may undergo splenectomy. Hemochromatosis, chronic hemolysis, and splenectomy are all found to increase …

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Augmentation of Infrared Microscopy of White Blood Cells and Medical Measures for Rapid and Accurate Diagnosis of Bacterial or Viral Infections in Febrile Pediatric Oncology Patients: An Expert System-Based Study

Uraib Sharaha, Yotam D. Eshel, Dima Bykhovsky, Julia Mazar et autres

Infectious diseases, a major contributor to high mortality rates, often exhibit similar symptoms, despite variations in immune responses to bacterial or viral infections. Rapidly differentiating bacterial infections from viral infections in febrile pediatric oncology patients is critical to reduce unnecessary antibiotic use …

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Erratum to: Characterization and genotype-phenotype correlation of patients with Fanconi anemia in a multi-ethnic population

Orna Steinberg‐Shemer, Tracie Alison Goldberg, Joanne Yacobovich, Carina Levin et autres

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Monitoring the efficacy of antibiotic therapy in febrile pediatric oncology patients with bacteremia using infrared spectroscopy of white blood cells-based machine learning

Yotam D. Eshel, Uraib Sharaha, Guy Beck, Gal Cohen-Logasi et autres

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Effect of Granulocyte Colony-Stimulating Factor on the Development of Spermatogenesis in the Adulthood of Juvenile AML Mice Model Treated with Cytarabine

Bara’ah Khaleel, Eitan Lunenfeld, Joseph Kapelushnik, Mahmoud Huleihel

Pediatric acute myeloid leukemia (AML) generally occurs de novo. The treatment of AML includes cytarabine (CYT) and other medications. The granulocyte-colony stimulating factor (GCSF) is used in the clinic in cases of neutropenia after chemotherapies. We show that the administration of GCSF …

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Clinically Complex LRBA Deficiency Due to a Founder Allele in the Georgian Jewish Population

Tal Freund, Sarah K. Baxter, Tom D. Walsh, Hana Golan et autres

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The effect of Socioeconomic ranks on the rate of Infections and Complications in the Treatment of Children’s Acute Lymphoblastic Leukemia

Karny Ilan, Tamar Niski Vagner, Ariela Knani, Joseph Kapelushnik

Socioeconomic differences in survival among children with acute lymphoblastic leukemia (ALL) have been reported widely.

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The effect of Socioeconomic ranks on the rate of Infections and Complications in the Treatment of Children’s Acute Lymphoblastic Leukemia

Karny Ilan, Tamar Niski Vagner, Ariela Knani, Joseph Kapelushnik

Socioeconomic differences in survival among children with acute lymphoblastic leukemia (ALL) have been reported widely.

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Effect of Chemotherapy Cytarabine and Acute Myeloid Leukemia on the Development of Spermatogenesis at the Adult Age of Immature Treated Mice

Bara’ah Khaleel, Eitan Lunenfeld, Joseph Kapelushnik, Mahmoud Huleihel

Acute myeloid leukemia (AML) accounts for around 20% of diagnosed childhood leukemia. Cytarabine (CYT) is involved in the AML treatment regimen. AML and CYT showed impairment in spermatogenesis in human and rodents in adulthood. We successfully developed an AML disease model in …

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Increased incidence of childhood lymphoma in children with a history of small for gestational age at birth

Roy Kessous, Eyal Sheiner, Guy Beck Rosen, Joseph Kapelushnik et autres

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