Barbora Ondrová

RIL EVALUATION ACROSS ANATOMICAL SITES

Vladimír Vondráček, Barbora Ondrová, Alexandra Haas, Samuel Kurucz et autres

concentration maxima ranging from 17.5 to 8 ppb (gradient=2.22ppb/Gy).Again, integrated signals and peaks scaled linearly with dose.Conclusions: Measured ozone concentrations were near the human detection threshold, thus ozone and ozone reaction products such as saturated and unsaturated aldehydes should be considered as …

cz (code pays fourni par la source)

Pediatric ependymoma in the molecular era: real-world experience with diagnostic correlation and long-term clinical outcomes

Kateřina Trková, Aleš Vícha, David Sumerauer, David R. Ghasemi et autres

PURPOSE: Real-world longitudinal data documenting the diagnostic impact of DNA methylation array (MA) profiling in pediatric ependymoma remain sparse. We report a single-center retrospective analysis evaluating MA-driven reclassification, molecular subgroup distribution, and long-term survival outcomes in a national pediatric referral cohort. METHODS: …

cz, de, ca, gb (code pays fourni par la source)

CLINICAL EXPERIENCE WITH PROTON RT IN PATIENTS WITH REFRACTORY OR RELAPSED B-CELL HEMATOLOGIC MALIGNANCIES TREATED WITH CAR T-CELL THERAPY

Michal Andrlík, Kateřina Dědečková, Lucia Kaliská, Jiří Kubeš et autres

cz (code pays fourni par la source)

Very Late-Onset Serious Chronic Adverse Effects After Radical Chemoradiotherapy for Anal Canal Cancer

Pavel Vítek, Jiří Kubeš, Barbora Ondrová, Alexandra Haas

Radical chemoradiotherapy has been used as a frontline treatment for squamous cell cancer of the anus for the last 30-40 years. Considerable acute and chronic adverse effects have been observed following radiotherapy using 2D and 3D techniques. A case of very late-onset …

cz (code pays fourni par la source)

Proton beam therapy for mediastinal Hodgkin lymphoma: A prospective study of clinical efficacy and safety

Kateřina Dědečková, Michal Andrlík, Heidi Móciková, Lucia Kaliská et autres

BACKGROUND: Proton beam therapy using pencil beam scanning is an advanced radiotherapy technique that utilises proton beams to precisely target tumours. It is known for its enhanced ability in sparing healthy tissue and potentially reducing toxicity. Clinical experience with pencil beam scanning …

cz, gb (code pays fourni par la source)

Temporal dynamics of lymphocytes in prostate cancer patients treated with proton therapy

Samuel Kurucz, Vladimír Vondráček, Vladimír Pekar, Michal Andrlík et autres

Radiotherapy can be both immunosuppressive and immunostimulatory. Radiation-induced lymphopenia (RIL) is an ongoing challenge in cancer treatment. We investigated weekly changes in the absolute lymphocyte count (ALC) during proton radiotherapy, evaluating the effects of different dosage, fractionation schedules, and pelvic node irradiation …

cz (code pays fourni par la source)

Proton pencil beam scanning radiotherapy in the postoperative treatment of p16 positive squamous cell tonsillar cancer – evaluation of toxicity and effectivity

Jiří Kubeš, Sarah Al-Hamami, Silvia Sláviková, Pavel Vítek et autres

PURPOSE: Patients with p16 positive tonsillar cancer (p16 + TC) have an excellent prognosis and long-life expectancy. Deintensification of therapy is a prevalent topic of discussion. Proton radiotherapy is one way to reduce radiation exposure and thus reduce acute and late toxicity. …

cz (code pays fourni par la source)

Clinical practice in European centres treating paediatric posterior fossa tumours with pencil beam scanning proton therapy

Laura Toussaint, Witold Matysiak, Claire Alapetite, Javier Aristu et autres

BACKGROUND AND PURPOSE: As no guidelines for pencil beam scanning (PBS) proton therapy (PT) of paediatric posterior fossa (PF) tumours exist to date, this study investigated planning techniques across European PT centres, with special considerations for brainstem and spinal cord sparing. MATERIALS …

dk, nl, fr, es, ch, gb, hu, pl, se, be, de, at, it, cz (code pays fourni par la source)

RADT-07. CLINICAL RESULTS, ACUTE AND EARLY LATE TOXICITY AFTER PROTON RADIOTHERAPY FOR PEDIATRIC MEDULLOBLASTOMA, RETROSPECTIVE ANALYSIS

Barbora Ondrová, David Sumerauer, Michal Zápotocký, Stanislava Hederová et autres

Abstract Craniospinal irradiation with boost to primary tumor site (and metastatic sites) is current radiotherapy standard for most patients diagnosed with medulloblastoma (MB). This treatment is effective, but survivors frequently develop long-term toxicity affecting the quality of life. Proton radiotherapy has the …

cz, sk, hr, bg (code pays fourni par la source)

QOL-42. ANALYSIS OF LATE EVENTS AFTER RADIATION THERAPY FOR PRIMARY PEDIATRIC BRAIN TUMORS

Kateřina Trková, Aleš Vícha, Lenka Krsková, Miroslav Koblížek et autres

Abstract BACKGROUND Late events after radiation therapy for primary brain tumors consist of secondary malignant neoplasms (SMN) and tumor recurrences. The incidence and biology of late events are not very well described. Therefore, we aimed to identify late events in our institutional …

cz (code pays fourni par la source)

PROTON PENCIL-BEAM SCANNING RADIOTHERAPY IN THE TREATMENT OF LOCALLY ADVANCED NON-ENDEMIC NASOPHARYNGEAL CANCER: TOXICITY AND DISEASE OUTCOME

Jiří Kubeš, Pavel Vítek, Vladimír Vondráček, Barbora Ondrová et autres

cz (code pays fourni par la source)

TEMPORAL DYNAMICS OF LYMPHOCYTES IN BREAST CANCER PATIENTS UNDERGOING PROTON RADIOTHERAPY

Sarah Al-Hamami Salih, Samuel Kurucz, Vladimír Vondráček, Vladimír Pekar et autres