Bin Sun

Design and synthesis of self-assembled ferulic acid-biotin nanoprodrugs with GSH/pH-responsive behavior and in vitro anticancer activity

Xiaoshuang Dai, Na Yao, Xinyu Liu, Ke Mei et autres

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Deep Learning-Enhanced Adaptive Correntropy Factor Graph Optimization for robust UUV navigation

Sen Cheng, Yanyan Wang, Bin Sun, Hao Zhu et autres

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Characterization of wheat bran protein/chitosan composite film: Study on the film-forming ability and bioactivities

Jing Han, Yiqian Song, Lei Li, Bin Sun et autres

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Insight into the mechanism of transformation of gluten protein agglomeration in the wheat flour-water batters: the view from concentration and mixing time

Hanrui Yang, Ying Xin, Jiaying Shang, Jiasheng WANG et autres

cn (code pays fourni par la source)

From Pharmacophore Models to Lead Compounds: Construction and Activity Evaluation of Novel Indoleamine 2,3‐Dioxygenase‐1 Inhibitors

Anli Zhang, Bin Sun

Indoleamine 2,3-dioxygenase-1 (IDO-1), as a crucial immunomodulatory target, plays a pivotal role in regulating immune function. In this study, the ligand-based pharmacophore model (HDAA) and the receptor-based pharmacophore model (HHDA) were respectively constructed, which could comprehensively reflect the spatial distribution characteristics of …

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Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang et autres

Abstract The residual risks of advanced atherosclerosis remain substantial despite current preventive strategies and pharmacotherapy. Circulating branched‐chain amino acids are biomarkers of cardiovascular disease risk. However, the mechanism of leucine in atherosclerosis progression remains unclear. Leucine transporter‐SLC7A5‐mediated leucine intake that promotes advanced …

cn, mo (code pays fourni par la source)

Network Pharmacology and Transcriptomic Analysis Reveal the Mechanism by Which Ginsenoside CK Remodels the Tumor Immune Microenvironment to Inhibit Liver Cancer Progression

Fangzhi Ye, Yong Wang, Qingyun Du, Bin Sun et autres

The study aimed to investigate the mechanism by which ginsenoside CK downregulates EZH2 to activate the dendritic cell-NK cell axis, promoting antitumor immunity in hepatocellular carcinoma (HCC). Potential targets of ginsenoside CK for HCC treatment were identified utilizing network pharmacology, followed by …

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Electronic structure modulation of metal based organic catalysts for photocatalytic H2O2 production

Wenhui Qi, Xiuyan Li, Shaonan Gu, Bin Sun et autres

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Building hollow multi-shell structured Zn2MnO4/CdS S-scheme heterojunction for boosted photocatalytic H2 production

Fangxuan Liu, Xiuyan Li, Bin Sun, Yanyan He et autres

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A conformationally adaptive cage with multiple guest recognition modes

Yong‐Liang Su, Songna Zhang, Yan Liu, Ming Liu et autres

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Hollow structured photocatalysts

Fangxuan Liu, Ziyan Liu, Guowei Zhou, Tingting Gao et autres

Photocatalysis technology, utilizing solar-driven reactions, is poised to emerge as a reliable strategy to alleviate environmental and energy pressures. Thus, whether the photocatalytic performance is excellent depends on the reasonable design of photocatalysts. By considering factors such as morphology engineering, band gap …

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Machine‐learning random forest algorithms predict post‐cycloplegic myopic corrections from noncycloplegic clinical data

Yansong Hao, Xianjiang Wang, Bin Sun, Jinyu Li et autres

SIGNIFICANCE: Machine learning random forest algorithms were used to predict objective refractive outcomes after cycloplegic refraction using noncycloplegic clinical data. A classification model predicted post-cycloplegic myopia and could be useful in screening, and a second regression model predicted post-cycloplegic refractive and could …

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