Rekha T. Chaudhary

An Exploratory Analysis of the Association Between Progesterone Use and Tumor-related Visual Deficit in Women With Meningioma

M Bailey, C. Avery, Matthew C. Hagen, Luke E. Pater et autres

Purpose Meningiomas may express estrogen/progesterone receptors (ER/PR), but hormonal risk is poorly characterized. We characterized association between progesterone supplementation and tumor-related visual deficits in premenopausal women receiving radiation for meningioma. Methods We performed a retrospective case-control study with primary endpoint of visual …

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Predictive capacity of mismatch repair status in the use of immune checkpoint inhibitors for the treatment of aggressive pituitary tumors and pituitary carcinomas: An illustrative case report and literature review

Natalie Ivey, Jeff F. Zhang, Abigail Zack, Aaron Kakazu et autres

Background: Aggressive pituitary tumors (APTs) and pituitary carcinomas (PCs) are rare tumors that often recur despite surgery and radiation. Immune checkpoint inhibitors (ICI) present a promising treatment alternative for these tumors; however, there is a paucity of information in the literature correlating …

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Symptomatic radiation necrosis after concurrent targeted therapy and stereotactic radiosurgery for brain metastases: a bicentric retrospective analysis

Ethan Steele, Jacob T. Hall, Kevin P. Lui, Rami Darawsheh et autres

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CNSC-89. BRAF/MEK INHIBITION IN THE TREATMENT OF BRAF-MUTANT HIGH-GRADE GLIOMAS: A FIVE-YEAR INSTITUTIONAL EXPERIENCE

Jeff Zhang, Natalie Ivey, Aaron Kakazu, Marissa Koscielski et autres

Abstract Treatment for high-grade gliomas following surgical resection usually involves administration of temozolomide and radiotherapy. However, small case series and few case reports have increasingly reported survival benefits in the usage of anti-BRAF therapy in a select population of BRAF-positive grade IV …

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Predictive Capacity of Mismatch Repair Status in the Use of Immune Checkpoint Inhibitors for the Treatment of Aggressive Pituitary Adenomas and Pituitary Carcinomas: Illustrative Case Report and Literature Review

Natalie Ivey, Jeff F. Zhang, Abby Zack, Aaron Kakazu et autres

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Radiation Necrosis, Pseudoprogression, and Enhancing Radiologic Changes after Photon or Proton Chemoradiotherapy for Grade 2-3 IDHmt Gliomas

Jose L. Ortega, T. MacDonald, Anthony E. Mascia, Timothy D. Struve et autres

Animated patient’s guide to melanoma: Assessing patient understanding, shared decision-making, and health outcomes.

Kyleigh LiPira, Michael B. Atkins, Rekha T. Chaudhary, Laura Korb Ferris et autres

9581 Background: Patients with melanoma who participate in informed, personalized-care discussions with their healthcare providers are better prepared to carry out shared decision-making (SDM) and achieve best attainable health outcomes. In a 2018 Cancer Registry Experience study of 114 melanoma survivors, a …

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NCMP-03. ASSOCIATION OF PROGESTERONE CONTRACEPTION WITH TUMOR-RELATED VISUAL IMPAIRMENT IN PREMENOPAUSAL WOMEN WITH MENINGIOMA REFERRED FOR RADIATION

M Bailey, C. Avery, Luke E. Pater, Timothy D. Struve et autres

Abstract BACKGROUND Meningiomas express ER/PR, but hormonal risk is poorly characterized and not always considered. We hypothesized that hormonal contraceptives lead to tumor-related visual deficits in premenopausal women referred for radiation. METHODS We conducted a retrospective case-control study with primary endpoint visual …

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NIMG-15. RAPID EARLY PROGRESSION AFTER SURGERY ON PRE-RADIATION PLANNING MRI FOR IDH-WILDTYPE GLIOBLASTOMA

Jonathan Sackett, Khadija Ahmed, Tim Struve, Luke E. Pater et autres

Abstract BACKGROUND Use of pre-RT planning MRI for glioblastoma (GBM) is inconsistent and not required by many clinical protocols. We performed a detailed volumetric analysis of rapid early progression (REP) on pre-RT planning MRI’s, hypothesizing that REP is associated with worse survival …

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Immune Checkpoint Inhibition for High Grade Meningiomas: A Systematic Review

Joel Kaye, John Na, Shravan C. Atluri, Natalie Ivey et autres

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Data from A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas

Pankaj B. Desai, Aniruddha Sunil Karve, Misam Zawit, Priyanka Arora et autres

AbstractPurpose: High-grade gliomas (HGG) carry a poor prognosis, with glioblastoma accounting for almost 50% of primary brain malignancies in the elderly. Unfortunately, despite the use of multiple treatment modalities, the prognosis remains poor in this population. Our preclinical studies suggest that the …

Data from A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas

Pankaj B. Desai, Aniruddha Sunil Karve, Misam Zawit, Priyanka Arora et autres

AbstractPurpose: High-grade gliomas (HGG) carry a poor prognosis, with glioblastoma accounting for almost 50% of primary brain malignancies in the elderly. Unfortunately, despite the use of multiple treatment modalities, the prognosis remains poor in this population. Our preclinical studies suggest that the …