Peter Iversen

Prospective evaluation of the PRIMARY score using [18F]PSMA-1007 PET/MRI in second-line prostate biopsies after negative MRI

Mads Ryø Jochumsen, Lise Medrud, André H. Dias, Mette Abildgaard Pedersen et autres

Abstract Purpose PSMA PET has been proposed for guiding targeted prostate biopsies. As the rate of clinically significant prostate cancer (csPCa) is positively correlated with PSA density (PSAd), a potential application for PSMA-guided biopsies may be men with negative MRI-first (PI-RADS-1-2) but …

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Comparison of tumour segmentation methods for dosimetry in [177Lu]Lu-PSMA I&T treated patients with metastatic castration resistant prostate cancer

Peter Staanum, Peter Iversen

Tumour dosimetry after radionuclide therapy using 177 Lu-labelled radiopharmaceuticals requires determination of the 177 Lu mean concentration, but this is challenging as tumours are often small, or 177 Lu activity is present in nearby organs or other tumours. Here we present a …

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Drug Utilisation of Radium-223 Under Routine Clinical Practice (DIRECT) in Europe: A Post-Authorisation Safety Study

Rachel Weinrib, David Martínez, Bianca Kollhorst, Ulrike Haug et autres

INTRODUCTION: Radium-223 is indicated for adults with metastatic castration-resistant prostate cancer (mCRPC) and symptomatic bone metastases, without visceral metastases, who progress after at least (≥) two lines of or are ineligible for other systemic therapies (besides luteinising hormone-releasing hormone analogues). Radium-223 is …

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Extraprostatic Needle Canal Recurrence of Localized Prostate Cancer After Nanoknife Electroporation Ablation Diagnosed with PSMA PET/MRI

Mads Ryø Jochumsen, Lise Medrud, Lars Anders Høst, Peter Iversen

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Positron Emission Tomography Imaging of Pheochromocytoma and Paraganglioma—18F-FDOPA vs Somatostatin Analogues

Andreas Ebbehøj, Peter Iversen, Stine Kramer, Kirstine Stochholm et autres

CONTEXT: Functional imaging with positron emission tomography (PET) scans is an essential part of the diagnostic workup for pheochromocytoma and paraganglioma (PPGL). The purpose of this review is to (1) provide a brief overview of functional imaging for PPGL, (2) summarize selected …

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Whole-body parametric mapping of tumour perfusion in metastatic prostate cancer using long axial field-of-view [15O]H2O PET

Mads Ryø Jochumsen, Nana Louise Christensen, Peter Iversen, Lars Christian Gormsen et autres

Abstract Purpose Tumour perfusion is a nutrient-agnostic biomarker for cancer metabolic rate. Use of tumour perfusion for cancer growth assessment has been limited by complicated image acquisition, image analysis and limited field-of-view scanners. Long axial field-of-view (LAFOV) PET scan using [15O]H2O, allows …

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Whole-body parametric mapping of tumour perfusion in metastatic prostate cancer using long axial field-of-view [15O]H2O PET

Mads Ryø Jochumsen, Nana Louise Christensen, Peter Iversen, Lars Christian Gormsen et autres

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Preoperative localization of water clear cell giant parathyroid adenoma: A case report

Farid Gossili, Simona Gauduseviciene, Daiva Erentaite, Peter Iversen et autres

Primary hyperparathyroidism commonly results from a solitary parathyroid adenoma. A water clear cell parathyroid adenoma represents a rare histological variant. This report presents the challenges of preoperative detection of a giant parathyroid adenoma, which was of the water clear cell variant. A …

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[18F]FDOPA PET/CT is superior to [68Ga]DOTATOC PET/CT in diagnostic imaging of pheochromocytoma

Peter Iversen, Stine Kramer, Andreas Ebbehøj, Esben Søndergaard et autres

BACKGROUND: Ga]DOTATOC PET/CT (DOTATOC) are widely used for detection of pheochromocytomas/paraganglioma (PPGL). However, direct comparisons of the performance of the two tracers are only available in small series. We conducted a retrospective comparative analysis of FDOPA and DOTATOC to assess their sensitivity …

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Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

Fredrik Wiklund, Elio Ríboli, Manuel Luedeke, Wayne D. Tilley et autres

Prostate cancer is a highly heritable disease with large disparities in incidence rates across ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer genome-wide association studies (107,247 cases and 127,006 controls) and identified 86 new genetic risk variants independently associated with …

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Early acquisition of [18F]FDOPA PET/CT imaging in patients with recurrent or residual medullary thyroid cancer is safe—and slightly better!

Mette Louise Gram Kjærulff, André H. Dias, Peter Iversen, Lars Christian Gormsen et autres

Abstract Purpose The aim of this study was to compare early (15 min) and late (60 min) [ 18 F]FDOPA PET/CT acquisition times in the detection of recurrence/residual disease in medullary thyroid cancer (MTC) patients. Materials and Methods Thirty-two dual-phase [ 18 …

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PSMA-Positive Low Malignant Gastrointestinal Stromal Tumor in the Stomach on F-18-PSMA-1007 PET/CT

Peter Iversen, Allan K. Hansen, Thorbjørn Hubeck‐Graudal, Lise Medrud et autres

A 76-year-old man with newly diagnosed high-risk prostate cancer was referred for primary staging with F-18-PSMA-1007 PET/CT. The PET/CT scan showed no lymph node or bone metastases, only localized disease within the prostate gland. Additionally, the F-18-PSMA PET/CT scan showed a PSMA-positive …

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