Jean Noël Nyemb

Erratum in: In vitro and molecular docking evaluation of apigenin-7-O-glucuronide from Psorospermum febrifugum as anti-inflammatory and predicted antiplasmodial compound

Fadimatou Abdourahman, Jean Noël Nyemb, Olga Nana, Boukli Hacene Faiza et autres

[This corrects the article DOI: 10.33393/dti.2026.3758.].

Cameroun, Algérie (code pays fourni par la source)

Antiplasmodial Potential of Compounds from the Bark of Mitragyna inermis (Rubiaceae): In Silico and In Vitro Studies Against LDH, PKG Enzymes and 3D7/Dd2 Strains

Adelphe Dounia, Jean Noël Nyemb, Roméo Toko Feunaing, Cyrille Tchuente Djoko et autres

Plasmodium falciparum is one of the parasites responsible for malaria, a serious and potentially deadly disease. Mitragyna inermis, a plant used to treat malaria in Africa, shows antiplasmodial activity against P. falciparum. Its extracts may target Lactate Dehydrogenase and Protein Kinase G, …

In vitro and molecular docking evaluation of apigenin-7-O-glucuronide from Psorospermum febrifugum as anti-inflammatory and predicted antiplasmodial compound

Fadimatou Abdourahman, Jean Noël Nyemb, Olga Nana, Boukli Hacene Faiza et autres

Introduction: Psorospermum febrifugum is traditionally used in Africa for the treatment of inflammation andmalaria. This study aimed to isolate and characterize a bioactive compound from its leaves, evaluate its anti-inflammatory activity, assess the antiplasmodial activity of the CH2Cl2/MeOH crude extract, and predict …

Cameroun, Algérie (code pays fourni par la source)

Molecular docking, dynamics simulations, and ADMET evaluation of some indole alkaloids and phenolic compounds from Campylospermum genus (Ochnaceae) as potential antiplasmodial and antimicrobial agents

Gaétan Bayiha Ba Njock, Jean Noël Nyemb, Robert Viani Kepdieu Tchebou, Aneela Khushal et autres

The increasing resistance of Plasmodium species and pathogenic bacteria to standard treatments highlights the need for the identification of new bioactive agents. Plants belonging to the genus Campylospermum (Ochnaceae), widely utilised in African traditional medicine, are a potential source of secondary metabolites …

Cameroun, pk, it (code pays fourni par la source)

Phytochemical and Pharmacological Studies of Campylospermum Species (Ochnaceae): An Updated Review

Gaétan Bayiha Ba Njock, Jean Noël Nyemb, Norbert Mbabi Nyemeck, Mc Jésus Kinyok et autres

The genus Campylospermum (Ochnaceae) comprises about 65 species, including several with a long ethnomedicinal history in tropical regions of the world. The present review compiles the information available in the literature (until January 2025) on ethnomedicinal recommendations, phytochemical profiles, and biological activities, …

Cameroun, fr, it (code pays fourni par la source)

β ‐Caryophyllene‐Rich Mercurialis perennis Leaf Essential Oil: GC–MS Profiling, Antioxidant Activity, Molecular Docking, and Molecular Dynamics Analysis

Chika Attama, Jean Noël Nyemb, Lawrence Luka, Hervé Landry Ketsemen et autres

ABSTRACT Mercurialis perennis L. (Euphorbiaceae) is an underexplored perennial herb traditionally used in complementary medicine. This study provides a comprehensive investigation of its leaf essential oil, integrating chemical profiling, in vitro antioxidant evaluation, and computational analyses. The essential oil was obtained by …

Nigéria, Cameroun, it (code pays fourni par la source)

New mercaptoacrylate derivatives and other constituents from the stem bark of Senegalia polyacantha: in vitro antioxidant and antiplasmodial activities with in silico target validation

Hermann Fomena, Gabrielle Ange Amang à Ngnoung, Peron Bosco Leutcha, Jeannette Nina Magoudjou Pekam et autres

Cameroun, tr, Burkina Faso, fr, lu, Afrique du Sud (code pays fourni par la source)

In silico inhibition mechanism of α -amylase and α -glucosidase by fragransinic acid and bellericagenin B, two compounds from Combretum fragrans F. Hoffm (Combretaceae)

Jean Noël Nyemb, Shafi Ullah Khan, Isaac Silvère Gade, Gaétan Bayiha Ba Njock et autres

Abstract Diabetes mellitus remains a global health challenge, necessitating novel therapeutic strategies to manage postprandial hyperglycemia. Inhibition of carbohydrate-hydrolyzing enzymes represents a key approach. This study investigates the inhibitory potential of phytochemicals from Combretum fragrans , a Cameroonian medicinal plant traditionally used …

Cameroun, fr, lu, it (code pays fourni par la source)

Antiplasmodial and antioxidant constituents from the stem bark of Haematostaphis barteri Hook.f. (Anacardiaceae): isolation and bioactivity evaluation

Dé Ndonaï-Koula Lafya Bodeboret Djimtoingar, Jean Noël Nyemb, Hervé Landry Ketsemen, Joël Abel Gwabeng Yaya et autres

Haematostaphis barteri Hook.f. (Anacardiaceae) is widely used in African traditional medicine for the management of malaria and other ailments. However, its active antiplasmodial constituents remain insufficiently characterized. To evaluate the antiplasmodial and antioxidant activities of the stem bark extract of H. barteri …

Cameroun, be, it (code pays fourni par la source)

Molecular docking and ADMET profiling of xanthones from Securidaca longepedunculata targeting oxidative stress in hypertension

Janvier Hinmara Tina, Cyrille Ngoufack Tagousop, Hervé Landry Ketsemen, Jean Noël Nyemb et autres

Hypertension remains a major global health challenge, with oxidative stress playing a pivotal role in its pathogenesis and complications. In this study, six naturally-occurring xanthones isolated from Securidaca longepedunculata roots were evaluated for their dual-action potential against hypertension via molecular docking with …

Cameroun, pk, be (code pays fourni par la source)

Bioactive constituents from Gardenia aqualla (Rubiaceae) stem bark as promising antibacterial agents: In vitro and in silico insights

Jean Noël Nyemb, Gaétan Bayiha Ba Njock, Taye B. Demissie, Japheth O. Ombito et autres

Continuing phytochemical investigation of the methanolic extract of Gardenia aqualla stem bark led to the isolation of a new fatty acid ester, henpentacontyl acetate (1), together with four known compounds: trans-apo-8'-carotenoic acid (2), ethyl (all-E)-8'-trans-apo-β-caroten-8'-oate (3), D-mannitol (4), and 2,3,4,5,6-pentahydroxyhexyl acetate (5). …

Cameroun, Botswana, pk, be, it (code pays fourni par la source)

A new limonoid, digsecokigelianolide, among the secondary metabolites from kigelia africana (lam.) benth. and evaluation of their antibacterial and antioxidant activity

Moïse Diguir, Isaac Silvère Gade, Peron Bosco Leutcha, Albert Atangana Fouda et autres

The present work investigates the phytochemical study and the antibacterial and antioxidant activities of Kigelia africana (Lam.) Benth. Column chromatography separation on silica gel of fractions led to the isolation of a new limonoid derivative named digsecokigelianolide (1), as well as nine …

Cameroun (code pays fourni par la source)