Alphafold Finetune - HLA3DBv2
Tianjian Liang, Ramamurty Pantula, Nikolaos G. Sgourakis
us (code pays fourni par la source)
0 citations
Zenodo (CERN European Organization for Nuclear Research)
Nikolaos G. Sgourakis
Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.
162Publications signalées
5133Citations signalées
4Affiliations récentes
Les institutions déclarées
Les domaines associés
Immunotherapy and Immune ResponsesT-cell and B-cell ImmunologyImmune Cell Function and Interactionvaccines and immunoinformatics approachesMonoclonal and Polyclonal Antibodies Research
Les publications récentes
Alphafold Finetune - HLA3DBv2
Tianjian Liang, Ramamurty Pantula, Nikolaos G. Sgourakis
us (code pays fourni par la source)
0 citations
Zenodo (CERN European Organization for Nuclear Research)
PepPred Parameters
Ramamurty Pantula, Tianyu Lu, Sean Wang, Wyatt Blackson et autres
PepPred Structural Similarity Predictor PepPred predicts structural similarity for 9-mer peptide antigens across HLA alleles. Methods related to this repository can be found in this manuscript: https://www.biorxiv.org/content/10.64898/2026.05.21.726655v1.full. Parameters This repository contains the .SIF file and parameters tar that are necessary for PepPred …
us (code pays fourni par la source)
0 citations
Zenodo (CERN European Organization for Nuclear Research)
PepPred: pMHC Conformation Similarity Predictor
Ramamurty Pantula, Tianyu Lu, Sean Wang, Tianjian Liang et autres
PepPred Structural Similarity Predictor PepPred predicts structural similarity for 9-mer peptide antigens across HLA alleles. Methods related to this repository can be found in this manuscript: https://www.biorxiv.org/content/10.64898/2026.05.21.726655v1.full. Runtime Options There are 2 .zip folders given here which provide alternate options for running …
us (code pays fourni par la source)
0 citations
Zenodo (CERN European Organization for Nuclear Research)
PepPred Parameters
Ramamurty Pantula, Tianyu Lu, Sean Wang, Wyatt Blackson et autres
PepPred Structural Similarity Predictor PepPred predicts structural similarity for 9-mer peptide antigens across HLA alleles. Methods related to this repository can be found in this manuscript: https://www.biorxiv.org/content/10.64898/2026.05.21.726655v1.full. Parameters This repository contains the .SIF file and parameters tar that are necessary for PepPred …
us (code pays fourni par la source)
0 citations
Zenodo (CERN European Organization for Nuclear Research)
PepPred: pMHC Conformation Similarity Predictor
Ramamurty Pantula, Tianyu Lu, Sean Wang, Tianjian Liang et autres
PepPred Structural Similarity Predictor PepPred predicts structural similarity for 9-mer peptide antigens across HLA alleles. Methods related to this repository can be found in this manuscript: https://www.biorxiv.org/content/10.64898/2026.05.21.726655v1.full. Runtime Options There are 2 .zip folders given here which provide alternate options for running …
us (code pays fourni par la source)
0 citations
Zenodo (CERN European Organization for Nuclear Research)
Ready-to-load MHC-I nanoparticles for high-throughput T cell screening studies
Hoang Anh T. Phan, Daniel Hwang, Michael C. Young, Shirley M. Sun et autres
MHC-I proteins present epitopic peptides to CD8+ T cells to elicit multifaceted adaptive immune responses. The affinity and avidity of interactions between peptide-MHC molecules and T-cell receptors (TCR) are fundamental parameters that contribute to the induction of activated or anergic T cell …
us (code pays fourni par la source)
1 citation
Science Advances
A miniaturized MR1 metabolite display system with native-like protein features
Photis Rotsides, Omkar Shinde, Julia N. Danon, Nikolaos G. Sgourakis
Major histocompatibility complex class I–related protein 1 (MR1) presents metabolite-derived antigens to mucosal-associated invariant T (MAIT) cells and other MR1-restricted T cells, playing a critical role in immune surveillance during infection and disease. Biochemical and structural studies of MR1 have been limited …
us, it (code pays fourni par la source)
0 citations
eLife
A miniaturized MR1 metabolite display system with native-like protein features
Photis Rotsides, Omkar Shinde, Julia N. Danon, Nikolaos G. Sgourakis
Major histocompatibility complex class I–related protein 1 (MR1) presents metabolite-derived antigens to mucosal-associated invariant T (MAIT) cells and other MR1-restricted T cells, playing a critical role in immune surveillance during infection and disease. Biochemical and structural studies of MR1 have been limited …
us, it (code pays fourni par la source)
0 citations
eLife
A generalizable system for antigenic peptide targeting across HLA-I allotypes
Wyatt Blackson, Ean L. Small, Shirley M. Sun, Omkar Shinde et autres
Abstract T cell receptors (TCRs) and TCR-mimicking antibodies recognize peptide antigens in the context of specific Human Leucocyte Antigen (HLA-I) allotypes, and the extreme polymorphism of the HLA locus limits the breadth of immunotherapy development. Key barriers include divergent molecular surfaces on …
us (code pays fourni par la source)
0 citations
bioRxiv (Cold Spring Harbor Laboratory)
PepPred: pMHC Conformation Similarity Predictor
Ramamurty Pantula, Tianyu Lu, Sean Wang, Tianjian Liang et autres
This repository contains required packages and scripts for PepPred, a pMHC conformational similiarty predictor. Model parameters can be downloaded from: https://zenodo.org/records/20076767.
us (code pays fourni par la source)
0 citations
Zenodo (CERN European Organization for Nuclear Research)
PepPred Parameters
Ramamurty Pantula, Tianyu Lu, Sean Wang, Po‐Ssu Huang et autres
This package includes model parameters for PepPred, AlphaFold FineTune, and Protpardelle.
us (code pays fourni par la source)
0 citations
Zenodo (CERN European Organization for Nuclear Research)
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