VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma
B.T. Teh, R. Saito, J. Todd Auman, W.Y. Kim et autres
Inactivation of the von Hippel-Lindau (VHL) E3 ubiquitin ligase protein is a hallmark of clear cell renal cell carcinoma (ccRCC). Identifying how pathways affected by VHL loss contribute to ccRCC remains challenging. We used a genome-wide in vitro expression strategy to identify …
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