Bruce E. Kendall

Insight into the mode of action of phytocannabinoids against ovarian cancer and glioblastoma

Hinanit Koltai, Bruce E. Kendall

Glioblastoma multiforme (GBM) is a subtype of glioma brain tumors and the most frequent, invasive, and lethal among them. Ovarian cancer (OC) is the most lethal gynecological malignancy and is frequently diagnosed only at an advanced stage. Cannabis sativa produces hundreds of …

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Bark traits and fire vulnerability in three California foothill oak species

Kaili Brande, Frank W. Davis, Bruce E. Kendall

Abstract Background Bark serves an important function in protecting trees from heat damage in fire-prone ecosystems. As fire increases in Mediterranean-climate systems, so does the need to understand fire adaptations of associated tree species, especially in important but understudied groups such as …

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Suppression of ovarian cancer -related angiogenesis processes by cannabis extract fraction in vascular endothelial cells is associated with reduced F-actin and focal adhesion points reorganization

Nurit Shalev, Eduard Belausov, Michelle A. Kendall, Yaron Shav‐Tal et autres

Angiogenesis, the growth of new vessels from existing ones to supply oxygen and nutrients requirement for tissue, is essential for tumor growth and development. Cannabis sativa extract fraction (F7) was shown previously to be cytotoxic to ovarian cancer (OC) cells. Here we …

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Triangulating habitat suitability for the locally extirpated California grizzly bear

Alex McInturff, Peter S. Alagona, Scott D. Cooper, Kaitlyn M. Gaynor et autres

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Integrated transcriptome and cell phenotype analysis suggest involvement of PARP1 cleavage, Hippo/Wnt, TGF-β and MAPK signaling pathways in ovarian cancer cells response to cannabis and PARP1 inhibitor treatment

Nurit Shalev, Michelle A. Kendall, Navin Kumar, Sudeep Tiwari et autres

Introduction:Cannabis sativa is utilized mainly for palliative care worldwide. Ovarian cancer (OC) is a lethal gynecologic cancer. A particular cannabis extract fraction ('F7′) and the Poly(ADP-Ribose) Polymerase 1 (PARP1) inhibitor niraparib act synergistically to promote OC cell apoptosis. Here we identified genetic …

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The role of geophysics in the discovery of the Gonneville PGE-NiCu-Co-Au Deposit, Julimar, Western Australia.

Jacob Paggi, Kevin Robert Frost, Bruce E. Kendall

The Gonneville deposit is a significant new PGE-nickel copper-cobalt-gold sulphide deposit discovered by Chalice Mining in 2020. Located only 70 km northeast of Perth, Western Australia, it represents the first major discovery of a PGE-rich orthomagmatic sulphide deposit hosted in the Julimar …

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Locating gaps in the California Current System ocean acidification monitoring network

Rae Taylor-Burns, Courtney Cochran, Kelly Ferron, Madison Harris et autres

Ocean acidification is a global issue with particular regional significance in the California Current System, where social, economic, and ecological impacts are already occurring. Although ocean acidification is a concern that unifies the entire West Coast region, managing for this phenomenon at …

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Analogies for a No-Analog World: Tackling Uncertainties in Reintroduction Planning

ElizabethS. Forbes, Peter S. Alagona, AJ Adams, Sarah E. Anderson et autres

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Within Reach? Habitat Availability as a Function of Individual Mobility and Spatial Structuring

Jason Matthiopoulos, John Fieberg, Geert M. Aarts, Frédéric Barraquand et autres

Organisms need access to particular habitats for their survival and reproduction. However, even if all necessary habitats are available within the broader environment, they may not all be easily reachable from the position of a single individual. Many species distribution models consider …

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Pest Control by Generalist Predators Depends on Prey Density and Predator Effectiveness

Elizabeth H. T. Hiroyasu, Sara M. Kross, Roger A. Baldwin, Bruce E. Kendall

Integrated Pest Management (IPM) strategies increasingly incorporate natural predators of pest species to reduce the abundance and persistence of pest species in agricultural settings. Specialist predators and parasitoids have been demonstrated to be successful tools to reduce the damage from invertebrate pest …

Environmental Heterogeneity and Plants

Gordon A. Fox, Bruce E. Kendall, Susan Schwinning

Comments to “Persistent problems in the construction of matrix population models”

Judy P. Che‐Castaldo, Owen R. Jones, Bruce E. Kendall, Jean H. Burns et autres

Author(s): Che-Castaldo, Judy; Jones, Owen R; Kendall, Bruce E; Burns, Jean H; Childs, Dylan Z; Ezard, Thomas HG; Hernandez-Yanez, Haydee; Hodgson, David J; Jongejans, Eelke; Knight, Tiffany; Merow, Cory; Ramula, Satu; Stott, Iain; Vindenes, Yngvild; Yokomizo, Hiroyuki; Salguero-Gómez, Roberto

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