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Jennifer Gatz, Amanda Okolo, Isaac A. Janson, Brandon M. Hardesty et autres
Survival for individuals with sickle cell disease (SCD) is increasing, and along with it the potential for comorbid conditions that may be caused by cumulative tissue damage. This paper examines the prevalence of comorbidities among individuals with SCD in Indiana and assesses …
Jennifer Gatz, Amanda Okolo, Isaac A. Janson, Brandon M. Hardesty et autres
Survival for individuals with sickle cell disease (SCD) is increasing, and along with it the potential for comorbid conditions that may be caused by cumulative tissue damage. This paper examines the prevalence of comorbidities among individuals with SCD in Indiana and assesses …
Jennifer Gatz, Amanda Okolo, Isaac A. Janson, Brandon M. Hardesty et autres
OBJECTIVE: Survival for individuals with sickle cell disease (SCD) is increasing, and along with it the potential for comorbid conditions that may be caused by cumulative tissue damage. This paper examines the prevalence of comorbidities among individuals with SCD in Indiana and …
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Brian E. Dixon, Muchiri E Wandai, Elisabeth Reese, Mengyu Di et autres
There are 7.74 million individuals living with sickle cell disease (SCD) globally, making it the most inherited blood disorder. Public health seeks to measure the epidemiology of SCD as it occurs in nations and among populations that are under-resourced and at-risk. Many …
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Amelia Hochreiter-Hufford, Jennifer Gatz, Amy Griggs, Ryan D. Schoch et autres
BACKGROUND: Recognizing the limitations of pre-market clinical data, regulatory authorities have embraced total product lifecycle management with post-market surveillance (PMS) data to assess medical device safety and performance. One method of proactive PMS involves the analysis of real-world data (RWD) through retrospective …
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Mark A. Gromski, Nicholas D. Dey, Binhan Wang, Jennifer Gatz et autres
Introduction: Multiple society guidelines recommend placing pancreatic stents for post-ERCP (endoscopic retrograde cholangiopancreatography) pancreatitis prophylaxis in select cases. There is limited data on spontaneous migration and time to migration of these devices. Methods: Data on consecutive patients where a pancreatic stent (Cook …
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John C. Byrd, Jennifer Gatz, Cynthia Lim Louis, Alice S. Mims et autres
BACKGROUND: We evaluated the frequency of genomic testing and treatment patterns by age category in patients with newly diagnosed (ND) acute myeloid leukemia (AML) treated in both academic- and community-based health systems within a single Midwestern State. METHODS: Retrospective analysis of data …
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Michael J. Fassett, Susan D. Reed, Kenneth J. Rothman, Federica Pisa et autres
OBJECTIVE: The APEX-IUD (Association of Perforation and Expulsion of Intrauterine Devices) study evaluated the association of postpartum timing of intrauterine device (IUD) insertion, breastfeeding, heavy menstrual bleeding, and IUD type (levonorgestrel-releasing vs copper) with risks of uterine perforation and IUD expulsion in …
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Mary S. Anthony, Xiaolei Zhou, Juliane Schoendorf, Susan D. Reed et autres
ABSTRACT Intrauterine device (IUD) expulsion is more common among women with heavy menstrual bleeding, parity, higher body mass index (BMI), younger age, dysmenorrhea, or immediate postabortion or postpartum insertion. The APEX-IUD study was an observational cohort study of 326,658 individuals examining the …
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Carla Rodriguez‐Watson, Natalie E. Sheils, Anthony Louder, Elizabeth Eldridge et autres
BACKGROUND: As diagnostic tests for COVID-19 were broadly deployed under Emergency Use Authorization, there emerged a need to understand the real-world utilization and performance of serological testing across the United States. METHODS: Six health systems contributed electronic health records and/or claims data, …
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Carla Rodriguez‐Watson, Anthony Louder, Carly Kabelac, Christopher M. Frederick et autres
BACKGROUND: Real-world performance of COVID-19 diagnostic tests under Emergency Use Authorization (EUA) must be assessed. We describe overall trends in the performance of serology tests in the context of real-world implementation. METHODS: Six health systems estimated the odds of seropositivity and positive …
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Mary S. Anthony, Xiaolei Zhou, Juliane Schoendorf, Susan D. Reed et autres
OBJECTIVE: To explore to what extent intrauterine device (IUD) expulsion is associated with demographic and clinical risk factors. METHODS: The APEX-IUD (Association of Perforation and Expulsion of IntraUterine Devices) study was a U.S. cohort study using electronic health records from three integrated …
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