I Made Jawi

Alveolar bone regeneration induced by hyaluronic acid in Wistar rats

I Putu Gede Andyka Yasa, I Made Jawi, I Made Muliarta

Objective: The Study aims to ascertain the effects of administering 0.8% HA gel on bone regeneration following alveolar bone damage. Methods: Samples were divided into two groups: P1 (control) and P2 (treatment). In P1, only alveolar bone damage was induced, while in …

The Role of Antioxidant Therapy in the Management of Type 2 Diabetes Mellitus: A Literature Review

Dewa Ayu Agung Alit Suka Astini, I Wayan Putu Sutirta Yasa, I Made Jawi, I Nyoman Wande

Background: Type 2 diabetes mellitus (T2DM) is a metabolic disease and has become a global problem due to the rapid increase in the number of cases. This disease is characterized by chronic hyperglycemia caused by insulin resistance and pancreatic beta cell dysfunction. …

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Profile Of Antihypertensive Drug Use In Patients With Coronary Artery Disease At Prof. Dr. I.G.N.G. Ngoerah General Hospital (RSUP) In 2023

Ida Ayu Alit Widhiartini, I Made Jawi

Background: Coronary heart disease (CHD) is often triggered by atherosclerosis, with hypertension as a major risk factor. Managing hypertension through lifestyle modification and pharmacological therapy, such as ACE inhibitors, ARBs, beta-blockers, CCBs, and diuretics, is important to prevent further complications. Objective: To …

Association between phase angle and ECW/TBW ratio with body composition in individuals with central obesity: a cross-sectional study

Agustinus I Wayan Harimawan, Anak Agung Sagung Mirah Prabandari, Desak Made Wihandani, I Made Jawi et autres

Background Central obesity is closely linked with increased metabolic risk, systemic inflammation, and adverse outcomes. Bioelectrical impedance analysis (BIA) provides phase angle (PhA) and extracellular water to total body water (ECW/TBW) ratio—non-invasive biomarkers reflecting cellular integrity and fluid distribution. However, their relationship …

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Non-Invasive Prenatal Testing with Next Generation Sequencing Methods in Birth Defect Pregnancy: A Pilot Study

Anom Suardika, Anak Agung Ngurah Jaya Kusuma, Ni Gusti Ayu Manik Ermayanti, Endang Sri Widiyanti et autres

BACKGROUND: Identification of cell-free foetal DNA (cffDNA) in maternal blood, combined with next-generation sequencing (NGS) advancement, has paved the way for non-invasive prenatal screening to detect foetal aneuploidies. However, there is limited evidence on its diagnostic accuracy when compared with gold-standard invasive …

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Karakteristik penderita karsinoma laring di Poliklinik THT-KL RSUP Prof. I. G. N. G. Ngoerah Denpasar periode tahun 2019 – 2023

I Ketut Suanda, I Made Jawi, I Gde Ardika Nuaba, Indra Lesmana et autres

Background: Laryngeal carcinoma is an increasingly prevalent head and neck malignancy in Indonesia, particularly among elderly males. Knowledge of patient characteristics is essential for guiding management strategies and prevention. Therefore, this study aims to describe the characteristics of laryngeal carcinoma patients at …

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Slow 0.9% NaCl Bolus Administration Reduces ANP, MMP-2, and Syndecan-1 Shedding in Septic Shock Rabbit Models

I Nyoman Budi Hartawan, Made Wiryana, I Made Jawi, I Nyoman Mantik Astawa et autres

Background: The optimal rate for fluid bolus administration in septic shock remains a critical and unresolved question. Rapid bolus administration is commonly practiced but has been linked to elevated levels of atrial natriuretic peptide (ANP), matrix metalloproteinase-2 (MMP-2), and syndecan-1 shedding, potentially …

Expression of CD8+ and Foxp3+ T Lymphocyte as Predictor for Response to Neoadjuvant Chemotherapy in Stage III Breast Cancer

I Nyoman Wawan Tirtha Yasa, I Wayan Sudarsa, I Wayan Niryana, Ni Putu Sriwidyani et autres

BACKGROUND: Neoadjuvant chemotherapy (NAC) in breast cancer is usually utilized to eradicate micro-metastasis, induce apoptosis in tumor cells, and reduce the primary tumor size, enabling surgical intervention. Recent studies have shown that tumor-infiltrating lymphocytes (TILs), especially cytotoxic CD8+ T cells and immunosuppressive …

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Light physical activity and vitamin D improve sperm quality of male Rattus norvegicus exposed to cigarette smoke

Mauricio Amaral, Bagus Komang Satriyasa, I Wayan Putu Sutirta Yasa, I Made Sudarmaja et autres

Background: Male infertility is a significant global health issue, with rising prevalence linked to environmental factors such as secondhand smoke, which impairs sperm quality. This study aimed to examine how light physical activity and vitamin D supplementation improved sperm quality in rats …

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Analysis of Q-Angle as a Risk Factor for Patellofemoral Pain Syndrome in Volleyball Athletes: A Cross-Sectional Study

Ni Ketut Evitri Widhiantari, M. Widnyana, I Made Jawi, Agung Wiwiek Indrayani

Introduction: Patellofemoral Pain Syndrome (PFPS) is a common knee injury caused by excessive loading during knee flexion, such as running or jumping, frequently experienced by volleyball athletes. One of the primary risk factors is an increased Q-angle, which leads to patellar maltracking …

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Pilot study on the effectiveness of Sidhakarya meditation in reducing malondialdehyde levels: an experimental approach

I Made Jawi, Cokorda Bagus Jaya Lesmana, Yenni Kandarini, Ida Bagus Yorky Brahmantya et autres

Introduction: Oxidative stress, caused by an imbalance between reactive oxygen species (ROS) and antioxidants, contributes to chronic diseases. Malondialdehyde (MDA), a marker of oxidative damage, is commonly used to assess this stress. Meditation, especially mindfulness practices, has shown potential in reducing oxidative …

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Oral administration Of Gedi Leaves Extract (Abelmoschus Manihot) Increased Glp-1 Serum and Decreased Fasting Glucose Level on Hyperglycaemia Male White Rat (Rattus Novergicus)

Erynne Gracia Monica Sheriman, I Made Jawi, I Made Winarsa Ruma