Claudia Meregalli

Predictores de falla de extubación en el proceso de liberación de la asistencia ventilatoria mecánica invasiva en pediatría

Jorge Palmeiro, Pedro Taffarel, Yamila Nociti, Verónica Laulhé et autres

Introduction: Invasive mechanical ventilation (IMV) in pediatric intensive care units (PICUs) is a ubiquitous practice; the weaning process is supported by predictors, none of which guarantees success. Objetive: To describe the weaning process from IMV and to determine the predictive factors of …

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Role of noninvasive ventilation in liberation from invasive mechanical ventilation in children: A single center retrospective analysis

Pedro Taffarel, Jorge Palmeiro, Yamila Nociti, Verónica Laulhé et autres

Background: Noninvasive respiratory support (NRS) modalities are used more frequently to reduce the risk of extubation failure. We aimed to describe the role and effectiveness of noninvasive ventilation (NIV) in the liberation from invasive mechanical ventilation (IMV). Subjects and Methods: This was …

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Spontaneous breathing trial in the weaning process from mechanical ventilation in pediatrics: outcome and predictive factors

Pedro Taffarel, Jorge Palmeiro, Yamila Nociti, Verónica Laulhé et autres

Introduction. spontaneous breathing trial (SBT) in weaning from pediatric invasive mechanical ventilation (IMV) is an endorsed practice, its positivity is based on clinical parameters; however, its results could be better documented. Objective. To describe the results of the SBT in the IMV …

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Optimising antibacterial utilisation in Argentine intensive care units: a quality improvement collaborative

Facundo Jorro Barón, Cecilia Loudet, Wanda Cornistein, Inés Suárez-Anzorena et autres

BACKGROUND: There is limited evidence from antimicrobial stewardship programmes in less-resourced settings. This study aimed to improve the quality of antibacterial prescriptions by mitigating overuse and promoting the use of narrow-spectrum agents in intensive care units (ICUs) in a middle-income country. METHODS: …

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Quality improvement collaborative for improving patient care delivery in Argentine public health sector intensive care units

Cecilia Loudet, Facundo Jorro Barón, Rosa Reina, María del Pilar Arias López et autres

BACKGROUND: The demand for healthcare services during the COVID-19 pandemic was excessive for less-resourced settings, with intensive care units (ICUs) taking the heaviest toll. OBJECTIVE: The aim was to achieve adequate personal protective equipment (PPE) use in 90% of patient encounters, to …

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Addressing the aftermath of the COVID-19 pandemic: A quality improvement collaborative to optimize the use of antibacterials in Argentine Intensive Care Units

Facundo Jorro Barón, Cecilia Loudet, Wanda Cornistein, Inés Suárez-Anzorena et autres

Abstract Background Reducing antimicrobial resistance is a global priority that become even more important after the COVID-19 pandemic. To date there is a scarce volume of evidence from antimicrobial stewardship programs from less resourced settings where this phenomenon is bigger. Our aim …

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Impact of the implementation of a sedation and analgesia protocol in a pediatric intensive care unit

Pedro Taffarel, Jesica Widmer, Ángeles Fiore, Claudia Meregalli et autres

Introduction. Adequate sedation and analgesia is essential in the management of patients requiring mechanical ventilation (MV). The implementation of protocols and their monitoring is recommended; mixed results on adherence and impact have been reported. Objectives. To assess the impact of the implementation …

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implementación de una lista de verificación mejora la adherencia a prácticas basadas en la evidencia en una unidad de terapia intensiva pediátrica

Pedro Taffarel, Ana Paula Rodríguez, Claudia Meregalli, Facundo Jorro Barón Facundo

Introduction: Adherence to evidence-based practices (EBP) allows better management of the health-disease process in critical ill patients, with a close relationship between compliance and the quality achieved. We set out to improve adherence to EBP in patients admitted to a Pediatric Intensive …

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A poor and delayed anti-SARS-CoV2 IgG response is associated to severe COVID-19 in children

Inés Sananez, Silvina Raiden, Silvia Algieri, Macarena Uranga et autres

BACKGROUND: Most children and youth develop mild or asymptomatic disease during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, a very small number of patients suffer severe Coronavirus induced disease 2019 (COVID-19). The reasons underlying these different outcomes remain unknown. METHODS: …

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Blood neutrophils from children with COVID-19 exhibit both inflammatory and anti-inflammatory markers

Vanesa Seery, Silvina Raiden, Silvia Algieri, Nicolás Grisolía et autres

BACKGROUND: Perhaps reflecting that children with COVID-19 rarely exhibit severe respiratory symptoms and often remain asymptomatic, little attention has been paid to explore the immune response in pediatric COVID-19. Here, we analyzed the phenotype and function of circulating neutrophils from children with …

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Multisystem inflammatory syndrome in children related to COVID-19: An update regarding the presentation of two critically ill patients

Pedro Taffarel, Jorro Barón, Ana Paula Rodríguez, Jesica Widmer et autres

Multisystem inflammatory syndrome in children related to COVID-19 is defined as the presence of persistent fever, inflammation, and organ dysfunction, with evidence of past or recent severe acute respiratory syndrome coronavirus 2 infection, and excluding other microbial causes. It overlaps with other …

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Blood Neutrophils from Children with COVID-19 Exhibit Both Inflammatory and Anti-Inflammatory Markers

Vanesa Seery, Silvina Raiden, Silvia Algieri, Nicolás Grisolía et autres

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