Francis Ajeneye

A retrospective audit of the use of O (RhD) negative red blood cells

Margaret Farinto, Francis Ajeneye

Emergency O (RhD) negative red blood cells (RBCs) are critical in the management of acute blood loss, especially in trauma and obstetric emergencies where the patient’s blood type is unknown or a delay in the provision of compatible units. Due to their …

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Direct Antiglobulin Test in Predicting the Severity of Hyperbilirubinemia and Haemolytic Disease of the Newborn

Natasha Ewart, Francis Ajeneye, L. K. GROVES

This study investigated the efficacy of the Direct Antiglobulin Test (DAT) reaction grades and the severity of hyperbilirubinaemia, in order to assist with the prediction and treatment of HDN. However, a weak correlation was found in this study. DAT significance may be …

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Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19

Hesham Abdelhady, Marwa Abdelrazik, Zakee Abdi, David Abdo et autres

IMPORTANCE: The evidence for benefit of convalescent plasma for critically ill patients with COVID-19 is inconclusive. OBJECTIVE: To determine whether convalescent plasma would improve outcomes for critically ill adults with COVID-19. DESIGN, SETTING, AND PARTICIPANTS: The ongoing Randomized, Embedded, Multifactorial, Adaptive Platform …

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

Obbina Abani, Ali H. Abbas, Fatima H. Abbas, Mustafa A. Abbas et autres

BACKGROUND: Many patients with COVID-19 have been treated with plasma containing anti-SARS-CoV-2 antibodies. We aimed to evaluate the safety and efficacy of convalescent plasma therapy in patients admitted to hospital with COVID-19. METHODS: This randomised, controlled, open-label, platform trial (Randomised Evaluation of …

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Convalescent Plasma and COVID-19: Ancient Therapy Re-emerged

Francis Ajeneye

Convalescent plasma has again re-emerged as a therapy during coronavirus disease (COVID-19) outbreaks currently use as a prophylactic or an interventional treatment in infected patients.Convalescent plasma has been used in the 20 th century confronting different infectious diseases where there was no …

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The critical push for traceability compliance: A District General Hospital experience

Francis Ajeneye

Blood remains one of the world’s vital substances. Blood and its products save millions of lives everyyear. Blood products are therapeutic and are derived from human whole blood, they are fragile,expensive and heavily freighted around the world. The continuing emergence of infectious …

Eosinopenia as a Diagnostic Marker in Covid-19?

Francis Ajeneye, Oladimeji Olofin

Eosinopenia is defined as a decrease of circulating eosinophils<0.01 × 109/l. Eosinopenia is mediated by adrenalglucocorticosteroids and epinephrine in acute stress, whereas inacute inflammatory states, this is not reliant upon the endocrinemechanisms. The use of eosinopenia as a marker is aencouraging observation …

Implementation and evaluation of a blood products traceability procedure in a District General Hospital

Francis Ajeneye

Aim: The study evaluated poor traceability compliance of blood products within a District General Hospital (DGH) and explored why the wards traceability compliance varied across the DGH. The study also explored risk factors that lead to poor traceability of blood products within …

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