Amanda Jowell

Improving and Sustaining Equity Content and Quality in Graduate Medical Education

Giovanna S. Jaen, Juliet Kim, Amanda Jowell, Caitlin Ravichandran et autres

ABSTRACT Background Medical education curricula may reinforce health inequities and bias, impacting clinical care. Interventions are needed to address these unintended consequences that contribute to health disparities. The Departmental Anti-Racism and Equity (DARE) educational initiative has been shown to improve the health …

us (code pays fourni par la source)

Cardiometabolic Health in Pregnancy

Colleen Harrington, Amy Sarma, Amanda Jowell, Jessica Passarelli et autres

Cardiometabolic health across the reproductive lifespan is a critical determinant of short-term pregnancy outcomes and long-term cardiovascular risk for both mother and offspring. Pregnancy serves as a unique physiological stress test and a key opportunity for primordial and primary prevention. Cardiometabolic risk …

us (code pays fourni par la source)

Development and Validation of a Clinical Polygenic Risk Report in U.S.-Based Health Systems for 8 Cardiovascular Conditions

Anika Misra, Amanda Jowell, Sara Haidermota, Emma Perez et autres

BACKGROUND: Polygenic risk scores (PRS) stratify inherited cardiovascular risk, but their path to clinical implementation remains unclear. OBJECTIVES: We aimed to develop and validate integrated PRS for 8 cardiovascular conditions and outline a framework for their clinical reporting. METHODS: We analyzed genotype …

us (code pays fourni par la source)

Not All Prognostic Tools Are Equal: A Sex-Specific Approach to ASCVD Primary Prevention

Amanda Jowell, Nishant Shah

us (code pays fourni par la source)

Abstract 4358030: Development and Validation of a Clinical Polygenic Risk Report for Cardiometabolic Disease in a US-Based Health System

Aniruddh P. Patel, Anika Misra, Amanda Jowell, Sara Haidermota et autres

Background: As genomic data becomes more readily available, there is growing demand for tools to translate genetic risk into actionable insights for patients. We introduce a novel clinical polygenic risk score (PRS) report for cardiometabolic disease, designed to provide trait-specific risk estimates …

us (code pays fourni par la source)

The cardiometabolic paradox in women

Amanda Jowell, Emily S. Lau

The prevalence of many metabolic disease traits is greater in men, but their associated relative risk for cardiovascular disease outcomes is greater in women. This paradox contributes to under-recognition of the excess metabolic-associated cardiovascular risks seen in women. The prevalence of many …

us (code pays fourni par la source)

Female-Specific Cardiovascular Risk Factors in Severe Hypercholesterolemia

Amanda Jowell, Sarah Urbut, So Mi Jemma Cho, Yixuan Liu et autres

[Figure: see text]

us (code pays fourni par la source)

Importance of Clinical, Laboratory, and Genetic Risk Factors for Incident CAD

Romit Bhattacharya, Christopher Marnell, So Mi Jemma Cho, Aniruddh P. Patel et autres

BACKGROUND: Prior work suggests modifiable cardiovascular risk factors (CRFs) account for 80% to 90% of the risk for incident myocardial infarction. The contributions of genetic and other novel CRFs have not been simultaneously assessed in contemporary data sets. METHODS: In the United …

us, it, kr, ca (code pays fourni par la source)

Genetic Risk and First-Trimester Cardiovascular Health Predict Hypertensive Disorders of Pregnancy in Nulliparous Women

Raiyan R. Khan, Amanda Jowell, Qi Yan, Itsik Pe’er et autres

us (code pays fourni par la source)

LIPID CONTROL AMONG PAROUS WOMEN WITH SEVERE HYPERLIPIDEMIA

Amanda Jowell, So Mi Cho, Michael C. Honigberg, Colleen Harrington

us (code pays fourni par la source)

ADVERSE PREGNANCY OUTCOMES AND PREMATURE MENOPAUSE ENHANCE CARDIOVASCULAR RISK AMONG WOMEN WITH SEVERE/FAMILIAL HYPERCHOLESTEROLEMIA

Amanda Jowell, Sarah Urbut, So Mi Cho, Pradeep Natarajan et autres

us (code pays fourni par la source)

Abstract 4140846: Racial Disparities in Low-Density Lipoprotein Cholesterol Control and Lipoprotein(a) Testing Among Young Adult Women with Severe Hyperlipidemia

Amanda Jowell, So Mi Cho, Christian Kraglund Andersen, Zhi Yu et autres

Background: Young adult women with severe hyperlipidemia (sHLD), or low-density lipoprotein cholesterol (LDL-C) ≥190 mg/dL, are less likely to achieve guideline-recommended LDL-C reduction than their male or older counterparts. Lipoprotein(a) [Lp(a)] can serve as a risk modifier of cardiovascular disease and may …

us (code pays fourni par la source)