Mila V Todorović-Tirnanić

Uptake of 68Ga-DOTATATE and 68Ga-DOTATOC in Primary Neuroendocrine Tumors, Metastases, and Normal Liver Tissue: Is There a Significant Difference?

Mila V Todorović-Tirnanić, Cees J. A. van Echteld, Milan M. Gajić, Richard Paul Baum

Abstract Purpose: Intrapatient comparison of in vivo distribution of two Ga-68-labeled somatostatin (agonist) analogues with different in vitro affinities for human somatostatin receptor (sstr) subtypes 2, 3, and 5 by determining their SUVmax values in normal liver, primary tumors, and metastases in …

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Platelet kinetics in patients with chronic immune thrombocytopaenia treated with thrombopoietin receptor agonists

Zlatko Pravdić, Nada Suvajdžić, Predrag Đjurdjević, Nikola Pantić et autres

Abstract Introduction Thrombopoietin receptor agonists (TPO‐RAs) increase platelet counts (PC) in the majority of patients with chronic immune thrombocytopaenia (ITP). Platelet kinetics study (PKS) might contribute to the understanding of mechanisms that lead to durable response. Objectives To evaluate the effects of …

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PS1491 PLATELET KINETICS IN PATIENTS WITH CHRONIC IMMUNE THROMBOCYTOPENIA TREATED WITH THROMBOPOIETIN RECEPTOR AGONISTS

Zlatko Pravdić, Mirjana Mitrović, Mila V Todorović-Tirnanić, Marijana Virijević et autres

Background: Chronic immune thrombocytopenia (ITP) is characterised by antibody‐mediated platelet destruction, shortened platelet survival (PS) and impaired platelets production. Platelet kinetic study (PKS) assesses in vivo the mean PS, platelet production and the platelet sequestration site. Thrombopoietin receptor agonists (TPO‐RA) increase platelets …

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Double trouble: Accessory spleen mimicking renal carcinoma recurrence identified by scintigraphy

Zorica Cvetković, Nada Suvajdžić, Mila V Todorović-Tirnanić

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GammaKey software for acquiring, storing, retrieving and processing images obtained by gamma camera — Benefits for clinical practice

Milica M. Janković, Mila V Todorović-Tirnanić, Ana Koljević Marković, Slobodanka Lj. Beatović et autres

The aim of this paper is to present the functionality and clinical application of developed GammaKey software for nuclear medicine imaging. GammaKey software consists of image acquisition module (compatibile with semi-analog gamma cameras), database, image processing module and network communication module. This …

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Intrapatient 68Ga-DOTATOC/68Ga-DOTATATE uptake comparison in primary neuroendocrine tumors, metastases and normal liver.

Mila V Todorović-Tirnanić, Milan M. Gajić, Richard Paul Baum

148 Objectives Two 68Ga-labeled somatostatin analogues [TOCT TOC exhibiting higher affinity for human somatostatin receptor 3&5, lower for 2] in vivo distribution comparison by determining standardized uptake values (SUVmax) in normal liver, primary gastroenteropancreatic neuroendocrine tumor (NET) and metastases (mets). Methods 76 …

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Clinical diagnosis of chronic immune thrombocytopenic purpura in pediatric population - is it always correct?

Mila V Todorović-Tirnanić, Dragana P. Sobic-Saranovic, Vera M. Artiko

1717 Objectives To investigate patophysiological mechanism of thrombocytopenia with 111In-oxinate labeled autologous platelets in children with clinical diagnosis of chronic immune thrombocytopenic purpura (ITP), to verify the diagnosis, and to predict the efficacy of the planned splenectomy. Methods 69 children (44 girls/25 …

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Comparison of 18F-FDG PET/CT and MDCT for staging/restaging of non-small cell lung cancer

Dragana P. Sobic-Saranovic, Igor Petrušić, Vera M. Artiko, Siniša U. Pavlović et autres

UNLABELLED: Multi-detector computed tomography (MDCT) is most commonly used for staging of non-small cell lung cancer (NSCLC). In recent years, 18F- fluorodeoxyglucose positron emission tomography combined with computed tomography (18F-FDG PET/CT) has also been used for the same purpose. Since studies comparing …

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Contemporary nuclear medicine diagnostics of neuroendocrine tumors

Mila V Todorović-Tirnanić, Vera M. Artiko, Smiljana V. Pavlovic, Dragana P. Sobic-Saranovic et autres

The new positron emission tomography (PET/CT) methods for neuroendocrine tumors detection are presented and compared with classic, conventional methods. Conventional methods use a gamma scintillation camera for patients with neuroendocrine tumor imaging, after intravenous injection of one of the following radiopharmaceuticals: 1) …

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Somatostatin receptors expression in normal prostate gland assessed by 68Ga-DOTATOC PET/CT

Mila V Todorović-Tirnanić, Milan M. Gajić, Vladimir Lj. Obradovic, Richard Paul Baum

63 Objectives The aim was to investigate somatostatin receptor (sstr) expression in normal prostate by determining the maximum standardized uptake value (SUVmax) of 68Ga-DOTATOC PET/CT in neuroendocrine tumor (NET) patients, without NET involvement of the prostate gland, in order to establish the …

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GammaKey system for improved diagnostics with gamma cameras

Milica M. Janković, Boris Pijetlović, Ana Koljević Marković, Mila V Todorović-Tirnanić et autres

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Gallium-68 DOTATOC PET/CT In Vivo Characterization of Somatostatin Receptor Expression in the Prostate

Mila V Todorović-Tirnanić, Milan M. Gajić, Vladimir B. Obradović, Richard Paul Baum

AIM: The aim was to investigate somatostatin receptor (sstr) expression in normal prostate by determining the maximum standardized uptake value (SUVmax) of (68)Ga-DOTATOC PET/CT in neuroendocrine tumor (NET) patients, without NET involvement of the prostate gland, for establishing the reference standard. METHODS: …

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