Karl O. A. Yu

1080: NOT JUST AN OPPORTUNIST

Sandhya Joshi, Erica Rider, Michael Bowler, Karl O. A. Yu

Introduction: Pneumocystis carinii pneumonia (PCP) is an opportunistic infection which can cause significant morbidity and mortality in immunocompromised patients if left untreated. It is much rarer in immunocompetent patients with more variable morbidity but similar mortality. Description: A previously healthy 17-year-old female …

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An Early Presentation: Familial Mediterranean Fever Diagnosed in a 3-Year-Old Child

Rabheh Abdul‐Aziz, B.F. Heycop ten Ham, Osama Almadhoun, Karl O. A. Yu

Familial Mediterranean fever is one of the most common hereditary autoinflammatory diseases with episodic serositis resulting in secondary amyloidosis, small bowel obstruction, and infertility if untreated. A 3-year-old boy of Syrian and Egyptian descent, with 3 healthy older siblings, presented at 28 …

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Contributors

Susan M. Abdel‐Rahman, Bahaa Abu-Raya, Kristina Adachi, Victoria Adeseye et autres

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Moraxella catarrhalis

Karl O. A. Yu, Anthony A. Campagnari, Nicole R. Luke‐Marshall

False-Positive Human Immunodeficiency Virus-1 Test Results With Rapid Seroreversion After Third-Trimester Tdap Booster Vaccination

Karl O. A. Yu, Seth R Glassman, Heather Link

BACKGROUND: False-positive and false-negative results in human immunodeficiency virus (HIV) testing are expected at some frequency. False-positive results have been reported in association with various conditions, including pregnancy, autoimmune disease, and infection. We present an atypical case of a pregnant patient receiving …

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51 Polymicrobial necrotizing pneumonia in a 3-year-old child with nearabsent pneumococcal antibody and mitogen interferon-γ responses

Gitanjali Rebello, Heather K. Lehman, Karl O. A. Yu

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Retrospective analysis of vertical Hepatitis C exposure and infection in children in Western New York

Ndeye Licka Dieye, Mine Varol, Shauna C. Zorich, Amy E. Millen et autres

BACKGROUND: Vertical transmission of hepatitis C virus (HCV) is the primary cause of hepatitis C in the pediatric population. Nonetheless, only a small proportion of HCV-exposed children are tested. This study aimed to measure the proportion of HCV-exposed children tested and infected …

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Antibody induction in mice by liposome-displayed recombinant enterotoxigenic Escherichia coli (ETEC) colonization antigens

Shiqi Zhou, Karl O. A. Yu, Moustafa T. Mabrouk, Dushyant Jahagirdar et autres

BACKGROUND: Enterotoxigenic Escherichia coli (ETEC) strains cause infectious diarrhea and colonize host intestine epithelia via surface-expressed colonization factors. Colonization factor antigen I (CFA/I), a prevalent ETEC colonization factor, is a vaccine target since antibodies directed to this fimbria can block ETEC adherence …

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Respiratory Infections in Patients with Primary Immunodeficiency

Heather K. Lehman, Karl O. A. Yu, C. Towe, Kimberly Risma

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Peptide-based Fusion Inhibitors for Preventing the Six-helix Bundle Formation of Class I Fusion Proteins: HIV and Beyond

Karl O. A. Yu, Mark D. Hicar

A number of different viral families have developed convergent methods to infect cells. Class I fusion proteins are commonly used by members of Arenaviridae, Coronaviridae, Filovirdae, Orthomyxoviridae, Paramyxoviridae, and Retroviridae. Class I viral fusion proteins are trimers that are involved in recognizing …

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COVID-19 associated Multisystem Inflammatory Syndrome in Children (MIS-C) guidelines; revisiting the Western New York approach as the pandemic evolves

Teresa Hennon, Karl O. A. Yu, Michelle Penque, Rabheh Abdul‐Aziz et autres

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Respiratory Failure in an Extremely Premature Neonate with COVID-19

Vasanth Kumar, Arun Prasath, Clariss Blanco, Patrick Kenney et autres

Coronavirus disease 2019 (COVID-19), a condition associated with SARS-CoV-2, typically results in mild infection in infants and children. However, children with risk factors such as chronic lung disease and immunosuppression have higher risk of severe illness from COVID-19. We report a case …

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