Accès ouvert
2026
data-paper
OpenAlex
Emmanuel Belchior, Colin Birch, Roland Ashford, Dipesh Davé et autres
In the United Kingdom (UK) and the Republic of Ireland (ROI), European badgers ( Meles meles ) are recognised as a reservoir host of Mycobacterium bovis (M. bovis) , which they can transmit to cattle. Badgers are also suspected to contribute to …
fr, gb, ie, es
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Sonya Middleton, Mahavir Singh, Michael Coad, Si Palmer et autres
ABSTRACT Bovine tuberculosis is an infectious livestock disease of global economic and zoonotic importance. Surveillance programs are largely dependent on the skin test that utilizes purified protein derivatives (PPDs) of tuberculin. PPDs suffer from a number of limitations regarding their production, characterization, …
gb, de
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Penny Barton, Sonya Middleton, Amanda O’Brien, John Clarke et autres
This study addressed the need in Great Britain for supplementary blood tests for deer and pig herds under movement restrictions due to confirmed Mycobacterium bovis infection—to enhance the overall sensitivity and reliability of tuberculosis (TB) testing and contribute to an exit strategy …
gb
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Andrew Robertson, Kate L. Palphramand, Robbie A. McDonald, Sonya Middleton et autres
In parts of the United Kingdom and Ireland, the European badger is a wildlife host for Mycobacterium bovis (the causative agent of bovine tuberculosis). Badger vaccination is one management option for reducing disease spread. Vaccination is currently achieved by parenteral vaccination of …
gb
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Ariane Payne, Sandrine Ruette, Mickaël Jacquier, Céline Richomme et autres
transmission between badgers and other species, and cattle in particular. An oral vaccine consisting of live Bacille Calmette-Guérin (BCG) contained in bait is currently under assessment for badgers, for which testing bait deployment in the field and assessing bait uptake by badgers …
fr, gb
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Sabine Steinbach, Sasan Jalili‐Firoozinezhad, Sreenidhi Srinivasan, Mariane B. Melo et autres
Bovine tuberculosis (bTB) is a disease of livestock with severe and worldwide economic, animal welfare and zoonotic consequences. Application of test-and-slaughter-based control polices reliant on tuberculin skin testing has been the mainstay of bTB control in cattle. However, little is known about …
gb, us
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Accès ouvert
2021
article
OpenAlex
Sonya Middleton, Sabine Steinbach, Michael Coad, Kevina McGill et autres
Tuberculin Purified Protein Derivatives (PPDs) exhibit multiple limitations: they are crude extracts from mycobacterial cultures with largely unknown active components; their production depends on culture of mycobacteria requiring expensive BCL3 production facilities; and their potency depends on the technically demanding guinea pig …
gb, ie
(code pays fourni par la source)
Accès ouvert
2020
preprint
OpenAlex
Sonya Middleton, Sabine Steinbach, Michael Coad, Kevina McGill et autres
Abstract Tuberculin Purified Protein Derivatives (PPDs) exhibit multiple limitations: they are crude extracts from mycobacterial cultures with largely unknown active components; their production depends on culture of mycobacteria requiring expensive BCL3 production facilities; and their potency depends on the technically demanding guinea …
gb, ie
(code pays fourni par la source)