Matheus Zschornack Strelow

Association of blood ptau‐217 with Memory Performance and APOE ε4 in Individuals with Subjective Cognitive Decline: insights from the BRASCODE Cohort

Manuella Edler Zandoná Giordani, Bárbara Loeblein Uebel, Victória Tizeli Souza, Simone Sieben da Mota et autres

BACKGROUND: Subjective cognitive decline (SCD), or self-perceived cognitive impairment, is a recognized risk factor for future cognitive decline and dementia. Analyzing Alzheimer's disease (AD) biomarkers in SCD populations could provide a means to identify preclinical AD and enable early intervention strategies. We …

br (code pays fourni par la source)

Alzheimer's Disease Plasma Biomarkers Performance in Brazilian Individuals

Eduardo R. Zimmer, Wyllians Vendramini Borelli, Pamela C.L. Ferreira, Wagner Scheeren Brum et autres

Alzheimer's disease (AD) biomarker research has largely concentrated on populations from the Global North. The emergence of blood-based biomarkers presents an opportunity to reduce this disparity. In this perspective presentation, I will present data on the performance of blood-based biomarkers in a …

br, ca, us (code pays fourni par la source)

Effect of cognitive reserve on cognitive performance in Subjective Cognitive Decline: insights from the BRASCODE Cohort

Manuella Edler Zandoná Giordani, Bárbara Loeblein Uebel, Victória Tizeli Souza, Simone Sieben da Mota et autres

BACKGROUND: Cognitive reserve refers to the brain's capacity to maintain performance despite pathology and may influence the risk of cognitive decline. Therefore, studying the effect of cognitive reserve on older adults with memory complaints can provide insights into their cognitive trajectories and …

br (code pays fourni par la source)

Diagnostic performance of Alzheimer’s disease blood and CSF biomarkers in a Brazilian cohort with low educational attainment

Wyllians Vendramini Borelli, Pâmela C.L. Ferreira, Wagner Scheeren Brum, João Pedro Ferrari‐Souza et autres

br, us, se, ca (code pays fourni par la source)

Diagnostic performance of Alzheimer’s disease blood biomarkers in a Brazilian cohort

Wyllians Vendramini Borelli, Pâmela C.L. Ferreira, Wagner Scheeren Brum, João Pedro Ferrari‐Souza et autres

Blood-based biomarkers (BBMs) have emerged as promising tools to enhance Alzheimer's disease (AD) diagnosis. Despite two-thirds of dementia cases occurring in the Global South, research on BBMs has predominantly focused on populations from the Global North. This geographical disparity hinders our understanding …

br, us, se, ca, uy (code pays fourni par la source)

Should the perspective of subjective memory decline differ between cognitively unimpaired individuals and their informants? Baseline results of the BRASCODE Cohort

Rhaná Carolina Santos, Sarah Vitória Bristot Carnevalli, Haniel Bispo De Souza, Victória Tizeli Souza et autres

Abstract Background Subjective Cognitive Decline (SCD) is characterized by cognitive complaints in cognitively unimpaired (CU) individuals. Its condition displays considerable heterogeneity etiologies, including neurodegenerative diseases. Our aim is to compare the memory complaints between patients with SCD and their informants in the …

br (code pays fourni par la source)

Influência da incapacidade funcional na qualidade de vida em pacientes com parkinsonismo atípico

Cíntia Costa Medeiros Martins, Nathalie Ribeiro Artigas, Amanda Pasqualotto, Artur Francisco Schumacher Schuh et autres

Objetivo: avaliar o nível de capacidade funcional e associar com a qualidade de vida (QV) de pacientes com parkinsonismo atípico (PA). Métodos: Trata-se de um estudo transversal com uma avaliação clínica por médico e fisioterapeuta para confirmação do diagnóstico de PA e …

br, uy, pt (code pays fourni par la source)

Brazilian Subjective Cognitive Decline (BRASCODE) Cohort: protocol and preliminary results

Raphael Machado Castilhos, Manuella Edler Zandoná Giordani, Simone Sieben da Mota, Bruno de Oliveira De Marchi et autres

br (code pays fourni par la source)

Informant and patient-reported subjective cognitive decline: a preliminary analysis of the Brazilian subjective Cognitive Decline Cohort

Raphael Machado Castilhos, Haniel Bispo De Souza, Manuella Edler Zandoná Giordani, Simone Sieben da Mota et autres

br (code pays fourni par la source)

An atypical presentation of neuroleptospirosis: a case report and literature review

Ana Letícia Amorim de Albuquerque, Monique Blauth Tovo, Rhaná Carolina Santos, Giovanna Polo et autres

Case presentation: Male, 43 years old, no known comorbidities. Presented with progressive caudal-cranial paresis in lower limbs. A week prior, he experienced acute urinary retention and episodes of intermittent fever. Neurological exam showed drowsiness, hypophonia, paraplegia associated with reduced strength in upper …

Informant‐ and Patient‐reported Subjective Cognitive Decline: a preliminary analysis of the Brazilian Subjective Cognitive Decline Cohort

Haniel Bispo De Souza, Victória Tizeli Souza, Manuella Edler Zandoná Giordani, Simone Sieben da Mota et autres

Abstract Background Subjective Cognitive Decline (SCD) is characterized by self‐experience of deterioration in cognitive performance in cognitive unimpaired (CU) individuals and may represent a preclinical stage of neurodegenerative diseases, especially Alzheimer’s disease (AD). Informant‐reported cognitive complaints appear to increase the risk for …

br (code pays fourni par la source)

Brazilian Subjective Cognitive Decline (BRASCODE) Cohort: protocol and preliminary results

Manuella Edler Zandoná Giordani, Victória Tizeli Souza, Simone Sieben da Mota, Bruno de Oliveira De Marchi et autres

BACKGROUND: Subjective Cognitive Decline (SCD) is a condition characterized by consistent cognitive complaints in cognitively unimpaired (CU) individuals and is associated with progressive cognitive impairment, especially in the context of Alzheimer's disease (AD). We aimed to show the study protocol and the …

br (code pays fourni par la source)