Marwa Mosaad Shakweer

Accelerating wound healing rates with Cucurbita pepo leaf extract loaded electrospun poly(methyl methacrylate)/Halloysite/Chitosan/CaCO₃ composite nanofibers through in vitro and in vivo assessments

Esraa B. Abdelazim, Shaza H. Aly, Shahira H. EL-Moslamy, Hend H. Mohamed et autres

Cucurbita pepo leaf extract (CPE) was incorporated into electrospun poly(methyl methacrylate)/ halloysite/chitosan/CaCO₃ (PMMA/Hal/CS/CaCO₃) composite nanofibers to develop a novel biomaterial for accelerating wound healing rates. The different nanofibrous scaffolds were successfully fabricated and characterized through scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy …

Égypte, sa (code pays fourni par la source)

Role of Twist and Vimentin as Epithelial-Mesenchymal Transition Biomarkers in Oral Squamous Cell Carcinoma: Relation to Cancer-Associated Fibroblasts

Eman Kh. Allam, Hamdy A.-M. Metwaly, Eman M.E.-D. Megahed, Marwa Mosaad Shakweer et autres

Various molecular pathways regulate oral squamous cell carcinoma (OSCC) progression, including epithelial-mesenchymal transition (EMT), which involves loss of epithelial adhesion, acquisition of mesenchymal traits, and upregulation of markers like Twist and Vimentin. Cancer-associated fibroblasts (CAFs) promote EMT through crosstalk with cancer cells. …

Égypte (code pays fourni par la source)

Enhancing wound healing with synergistic dual-drug electrospun roflumilast and L-arginine loaded PLA/PVA nanofibers through fabrication, optimization, and in vivo assessment

Samar A. Salim, Abdullah M. M. Elbadry, Esraa B. Abdelazim, Tasneem Abed et autres

Current trends in improved wound management emphasize the development of dual-drug-loaded electrospun nanofibrous scaffolds. Herein, electrospun dual-drug loaded PLA/PVA nanofibrous scaffolds, incorporating roflumilast, a selective phosphodiesterase-4 inhibitor with anti-inflammatory activity, and L-arginine, a precursor to nitric oxide with stimulating activity towards wound …

Égypte, sa (code pays fourni par la source)

Corrigendum to “Pinocembrin protects against cisplatin-induced liver injury via modulation of oxidative stress, TAK-1 inflammation, and apoptosis” [Toxicology and Applied Pharmacology, Volume 502, September 2025, 117433].

Samar F. Darwish, Sherif S. Abdel Mageed, Abdulla M. A. Mahmoud, Aya A. El-Demerdash et autres

Égypte (code pays fourni par la source)

Wound Healing in Wistar Rat Potential Treatment Using Magnetic Nanoparticles Coated with Bioplastic Produced from Desmonostoc muscorum

Olfat M. A. Salem, Ahmed Hassan Ibrahim Faraag, Fatma Abd El Lateef Gharib, Suzy N. Hanna et autres

Abstract Chronic wound management remains a significant clinical challenge due to persistent infections and delayed tissue regeneration. In this study, the development and the evaluation of polyhydroxyalkanoate-coated magnetic nanoparticles (PHA-MNPs) derived from the cyanobacterium Desmonostoc muscorum as a novel topical agent for …

Égypte (code pays fourni par la source)

Photocrosslinkable Morin-loaded gelatin-g-GMA composite hydrogel for accelerating burn wound healing: in vitro and in vivo assessments

Amr Negm, Samar A. Salim, Tasneem Abed, Marwa Mosaad Shakweer et autres

studies using a THP-1-derived M1 macrophage model, showed that the Morin-loaded hydrogel formulations GH-5, GH-6, and GH-7 demonstrated a potent, concentration-dependent suppression of key M1 inflammatory mediators including nitric oxide (NO), IL-1β, and IL-6. This anti-inflammatory effect was mechanistically linked to the …

sa, Égypte, kr (code pays fourni par la source)

Essential oils-based nanoemulsion formulation boosts hair growth in C57BL/6 mice as compared to minoxidil 2%

Mohamed I. Mahmoud, Omar Talaat, Adel A. Ghandour, Abdulrahman Mohamed et autres

Developing effective and safe natural formulations to promote hair growth presents a significant opportunity in cosmetic and pharmaceutical sciences. This study aimed to formulate and evaluate a nanoemulsion containing a blend of lavender, peppermint, and rosemary essential oils (LPR) for enhanced hair …

Égypte (code pays fourni par la source)

Characterization of PDL1 Expression in High Grade Endometrial Carcinoma across the Spectrum of Tumor Stage and Patient Survival and Other Clinicopathological Features

Ahmed Mahmoud Elhusainy, Marwa Mosaad Shakweer, Esraa Elsayed

Pinocembrin protects against cisplatin-induced liver injury via modulation of oxidative stress, TAK-1 inflammation, and apoptosis

Samar F. Darwish, Sherif S. Abdel Mageed, Abdulla M. A. Mahmoud, Aya A. El-Demerdash et autres

Égypte (code pays fourni par la source)

Diagnostic Value of Combined BCOR, Cyclin D1, and CD10 in Differentiating Endometrial Stromal Sarcoma From Other Uterine Spindle Cell Lesions

Mariam B. Abouelkhair, Marwa Mosaad Shakweer, Malames Mahmoud Faisal, Magda H. Nasreldin et autres

Uterine spindle cell lesions share a dilemmatic overlapped features that needed to be addressed by the pathologist to reach a conclusive accurate diagnosis for its prognostic value and different management decisions. Usage of combined IHC panel can be an aiding guiding tool …

Égypte (code pays fourni par la source)

A prospective study to assess the clinicopathological and prognostic value of BRAF V600E mutation in metastatic colorectal cancer

Mona Taher Aboulfadl, Marwa Mosaad Shakweer, Wesam Reda Elghamry

Introduction: BRAF is a protein kinase downstream of RAS in the RAS-RAF-MEK-ERK kinase pathway, the prevalence of BRAF mutation might be underestimated, while it is considered a major negative prognostic marker and is associated with resistance to standard chemotherapeutic regimens in metastatic …

Égypte (code pays fourni par la source)

Prospective Study to Assess the Clinicopathological and Prognostic Value of BRAF V600E Mutation in Metastatic Colorectal Cancer

Mona Taher ELsaeed, Mohamed Y. Mostafa, Marwa Mosaad Shakweer, Wesam Reda Elghamry

Abstract Background BRAF is a protein kinase downstream of RAS in the RAS-RAF-MEK- ERK kinase pathway. The majority (>95%) of BRAF mutations in metastatic colorectal cancer (mCRC) is the BRAFV600E mutation, which is considered an important negative prognostic marker and is associated …

Égypte (code pays fourni par la source)