Bruno Maria Moerschbacher

Integrated risk assessment reveals low biological activity of RNA-based crop protection formulations across plant and non-target systems

Moritz Dobrowitsch, Sandra Friedrich, Jonas Noetzold, Maria Bender et autres

Abstract RNA-based crop protection products are considered promising alternatives to conventional pesticides due to their high target specificity and selectivity profile. While current risk assessments mainly focus on sequence-dependent off-target effects, potential sequence-independent effects of RNA molecules and formulation components remain poorly …

de, kz (code pays fourni par la source)

Chitinase-3-like protein 1 decodes chitosan acetylation patterns into toll-like receptor 2 signaling through heparan sulfate

Alexandra Großdorf, Sina Nabil, Carlotta Imelmann, Margareta J. Hellmann et autres

Abstract Chitinase-3-like protein 1 (CHI3L1), which is associated with a wide range of inflammatory diseases, lacks chitinase activity but retains the ability to bind chitin and chitosan. Chitin is a major component of fungal cell walls, whereas chitosan is used in biomedicine. …

de, Égypte, fr, no (code pays fourni par la source)

Immunoengineered Chitosanase-Produced Chitosan Oligomers for Elevating Plant Resistance to Viral Infection

Soofia Khanahmadi, Ratna Singh, Judith Ryll, Naivy Y Nava Cruz et autres

Abstract Chitooligomers can act as plant biostimulants or biopesticides, but today’s chitosan-based agro-biologics often lack sufficient efficacy. This is due to a lack of scalable production processes for structurally well-controlled chitosans combined with a limited understanding of structure-function relationships. Chitosans differ in …

de, ca (code pays fourni par la source)

Domain gain or loss in a fungal chitinase enables specialization towards antagonism or immune suppression

Ruben Eichfeld, Asmamaw Bidru Endeshaw, Margareta J. Hellmann, Taim Nassr et autres

Effector proteins orchestrate interactions that determine host compatibility and microbial competition. Among these are microbial chitinases, widespread enzymes involved in nutrient acquisition, fungal cell-wall remodelling, and antagonism, yet how their functions diversify across ecological roles remains unclear. Here, we show that modular …

de (code pays fourni par la source)

Chitosan production methods influence receptor-mediated immune responses but not target-mediated antimicrobial bioactivities

Margareta J. Hellmann, Katharina Eickelpasch, Alexandra Großdorf, Pedro Barreto et autres

Chitosans are promising polysaccharides for the growing bioeconomy, but their numerous bioactivities depend on their structural parameters. Whereas researchers are currently unraveling the influence of the degree of polymerization and the fraction and pattern of acetylation on the properties and activities of …

de, kz (code pays fourni par la source)

Degree of acetylation of chitosans determined by size exclusion chromatography coupled to UV and refractive index detection

Stefan Cord‐Landwehr, Margareta J. Hellmann, Bruno Maria Moerschbacher

Chitin is one of the most common biopolymers whose partial deacetylation leads to chitosans consisting of the two β-1-4-linked units N -acetyl- d -glucosamine and glucosamine. These vary in their relative occurrence defined by the degree of acetylation (DA) which has a …

de, kz (code pays fourni par la source)

Performance and nutrient composition of black soldier fly larvae fed diets with various protein concentrations throughout the life cycle

Laura Schneider, Benson Kisinga, N.S. Stöhr, T Stiem et autres

Standardised rearing of black soldier fly (BSF, Hermetia illucens) larvae to utilise low-value organic substrates is gaining increasing interest in the context of sustainable animal production. The present study hypothesised that varying dietary protein concentrations would affect the growth performance and nutrient …

de, kz, us (code pays fourni par la source)

Cymbopogon winterianus essential oil as an alternative source for producing terpenic esters with potential plant-protective antifungal activity using lipase immobilized on a lignin composite

Carlos Alberto Chaves Girão Neto, Carolin G. Richter, Isabel Cristina Medeiros Prasilde, Kirley Marques Canuto et autres

br, kz (code pays fourni par la source)

Correction: Engineering of a chitin deacetylase to generate tailor-made chitosan polymers

Martin Bonin, Antonia L. Irion, Anika Jürß, Sergi Pascual et autres

[This corrects the article DOI: 10.1371/journal.pbio.3002459.].

Domain gain or loss in fungal chitinases drives ecological specialization toward antagonism or immune suppression

Ruben Eichfeld, Asmamaw Bidru Endeshaw, Margareta J. Hellmann, Bruno Maria Moerschbacher et autres

Abstract The evolutionary origins of fungal effector proteins remain poorly understood, particularly how structural changes reprogram antimicrobial enzymes into host-adapted immune suppressors. Here, we show that domain modularity drives ecological specialization in chitinase effectors of the beneficial root endophyte Serendipita indica . …

de (code pays fourni par la source)

Cell walls of filamentous fungi – challenges and opportunities for biotechnology

Katharina J Ost, Mounashree Student, Stefan Cord‐Landwehr, Bruno Maria Moerschbacher et autres

The cell wall of filamentous fungi is essential for growth and development, both of which are crucial for fermentations that play a vital role in the bioeconomy. It typically has an inner rigid core composed of chitin and beta-1,3-/beta-1,6-glucans and a rather …

de, nl (code pays fourni par la source)

First evidence of cryo-milling enhancing enzymatic production of chitooligosaccharides from chitin biomass

Saumashish Mukherjee, Stefan Cord‐Landwehr, Tirupaati Swaroopa Rani, Lal Duhsaki et autres

in, de (code pays fourni par la source)