Marwan Najjar

Long-term seizure and functional outcomes following peri-insular hemispherotomy

Badiee Moussa, Khaled Alok, Omar Nawfal, Marwan Najjar et autres

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Extradural cervical spinal meningioma without myelopathy

Mohamad Nabih El Houshiemy, Wael Ali Shouman, Sarah Kawtharani, Marwan Najjar

Background: Only 2.5-3.5% of all spinal meningiomas are extradural. Case Description: A 45-year-old female presented with chronic neck pain and bilateral arm numbness but was otherwise neurologically normal. The cervical magnetic resonance (MR) imaging revealed a right-sided extradural extramedullary lesion extending from …

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Temporalis Muscle Cavernous Hemangioma in a Pediatric Patient

Asmaa Kebbe, Mohamad Nabih El Houshiemy, Khaled Sidani, Sarah Kawtharani et autres

Background: Temporalis muscle hemangiomas are an uncommon entity, even among the rare incidences of intramuscular hemangiomas. They are frequently identified as round, painless, soft lesions beneath the skin that have been growing slowly over time. A preliminary diagnosis can be made based …

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Impact of re-operation on progression-free survival in patients with recurrent GBM: Experience in a tertiary referral center

Houssein Darwish, Tamer Diab, Sarah Kawtharani, Bader Ali et autres

BACKGROUND: Reoperation for patients with recurrent glioblastoma multiforme (GBM) is a highly debated topic within the medical community. GBM is known for its aggressive nature and poor prognosis, with most patients experiencing tumor recurrence despite initial treatments. Some studies suggest a survival …

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Elucidating the clinical and genetic spectrum of inositol polyphosphate phosphatase INPP4A-related neurodevelopmental disorder

Lettie E. Rawlins, Reza Maroofian, Stuart J Cannon, Muhannad Daana et autres

Purpose Biallelic INPP4A variants have recently been associated with severe neurodevelopmental disease in single-case reports. Here, we expand and elucidate the clinical-genetic spectrum and provide a pathomechanistic explanation for genotype-phenotype correlations. Methods Clinical and genomic investigations of 30 individuals were undertaken alongside …

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Association of Prostate-Specific Antigen With Age, Digital Rectal Examination, and Lower Urinary Tract Symptoms in the Lebanese Population: A Cross-Sectional Study

Yehya Tlaiss, Marc Jreij, Mohamad Tlais, Zahi F Yammine et autres

BACKGROUND: Prostate cancer (PCa) is a leading cause of mortality in men worldwide. Prostate-specific antigen (PSA) testing is a standard method for PCa detection, yet its association with age, digital rectal examination (DRE) results, and lower urinary tract symptoms (LUTS) remains understudied, …

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Simultaneous sampling of both cingulate gyri using a single interhemispheric depth electrode: A technical note

Sahar Farhat, Jawad Melhem, Houssein Darwish, Shadi Bsat et autres

Background: Simultaneous sampling of the cingulate gyri through a single depth electrode inserted underneath the falx cerebri is clinically useful in certain cases of drug-resistant epilepsy. However, the frequency at which each region of the cingulate gyri - namely, anterior, middle, and …

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Primary alveolar rhabdomyosarcoma of the brain: a case report

Layal Al Mahmasani, Marwan Najjar, Roula Hourany, Abeer Tabbarah et autres

BACKGROUND: Primary brain rhabdomyosarcoma is a rare primary brain malignancy with few case reports. The vast majority of cases of primary brain rhabdomyosarcoma occur in pediatric patients, and immunohistochemistry can distinguish it from embryonal subtypes; however, few cases of primary brain rhabdomyosarcoma …

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Scrotal migration of the distal end of the ventriculoperitoneal shunt: Is there a role for early closure of patent processus vaginalis in the pediatric population?

Houssein Darwish, Sarah Kawtharani, Mohamad Housheimy, Hiba Fadlallah et autres

Background: Ventriculoperitoneal shunt (VP) insertion is one of the surgical treatments for patients with hydrocephalus. Infection, malfunction, catheter migration, hernia development, equipment failure, CSF subcutaneous collection and peritoneal pseudo cyst formation are considered to be the main complications of this procedure. Case …

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Symptomatic intraoperative middle cerebral artery vasospasm after anterior temporal lobectomy for refractory epilepsy: An illustrative case and review of the literature

Louna Ftouni, Charbel Moussalem, Khaled Sidani, Mohammad Houshiemy et autres

Cerebral vasospasm, defined as the reversible constriction of cerebral arteries, is a deleterious complication, most related to aneurysmal subarachnoid hemorrhage. Although vasospasm can occur in the setting of traumatic subarachnoid hemorrhage, brain tumor resection, ruptured arteriovenous malformation with intraventricular extension, and other …

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Head Trauma in the Pediatric Population

Elias Elias, Marwan Najjar

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A rare case of metastatic colon cancer to the pineal region: A case report

Sarah Kawtharani, Charbel Moussalem, Mohamad Nabih El Houshiemy, Elias Horanieh et autres

Background: Colorectal cancer is the third most common cancer and the third most leading cause of death in the United States with brain being a rare site for metastasis and the pineal region being a rarer site to manifest. Case Description: We …

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