Jiayin Tian

Three New Natural Compounds from Portulaca oleracea and their Bioactivities

Pengyan Liu, Jiayin Tian, Yingdai Zhao, Jing Liu et autres

cn (code pays fourni par la source)

IDHP Mitigates LPS-Induced Cardiomyocyte Injury via the GAS6/Axl-AMPK Axis: A Multi-Target Strategy Counteracting Inflammation, Oxidative Stress, and Apoptosis

Junmin Chen, Yijie Wang, Xiumei Li, Jiayin Tian et autres

Background: Sepsis-induced myocardial injury (SIMI) significantly contributes to sepsis-related mortality, yet effective therapies remain limited. This study investigated the cardioprotective potential of isopropyl 3-(3,4-dihydroxyphenyl)-2-hydroxypropanoate (IDHP), a bioactive metabolite from Salvia miltiorrhiza, focusing on its mechanism via the GAS6/Axl signaling axis in lipopolysaccharide …

cn (code pays fourni par la source)

Protective effects of Ginkgolide B on myocardial ischemia reperfusion injury: role of the GAS6/Axl signaling pathway

Hai Liu, Wangrui Lei, Yeqing Ren, Jiayin Tian et autres

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Identification of aldose reductase inhibitors from the flowers of Tussilago farfara using PCN-222 metal-organic framework-based immobilization-free affinity selection coupled with high-performance liquid chromatography

Zhaoyang Wu, Jiayin Tian, Xuelian Xin, Soon Sung Lim et autres

kr, cn (code pays fourni par la source)

Mangiferin Attenuates Myocardial Ischemia Reperfusion Injury by Regulating the GAS6 /Axl Signaling Pathway

Aizhen Zhao, Wangrui Lei, Jiayin Tian, Xiaopeng Wu et autres

ABSTRACT Ischemia reperfusion‐induced myocardial injury is a prominent pathological feature in patients with coronary artery disease, contributing to significant mortality and morbidity rates. Mangiferin (MGF), the main active ingredient extracted from Anemarrhena asphodeloides Bge, has anti‐inflammatory, anti‐oxidation, anti‐diabetes, and anti‐tumor effects. The …

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Pharmacological activity, phytochemistry, and organ protection of lithospermic acid

Wenwen Yang, Jiayan Li, Jiayin Tian, Xiaoyi Liu et autres

Lithospermic acid (LA) is a water-soluble phenolic acid compound extracted and separated from the dried root and the rhizome of Salviamiltiorrhiza Bge (Labiatae), possessing multiple biological activities. Firstly, in terms of pharmacological activities, LA has been proven to possess anti-inflammatory, antioxidant, autophagy …

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A new alkaloid from Portulaca oleracea L. with its anti-inflammatory activity

Junjie Yao, Lina Wang, Peishan Liu, Mingyang Song et autres

Abstract A new isoindole alkaloid, 6-hydroxy-2-(4′′′-hydroxy-3′′′-methoxyphenethyl)-4-(4′-hydroxy-3′-methoxyphenyl)-7-methoxy-1H-benzo[f]isoindole-1,3(2H)-dione, named oleraisoindole B was isolated from Portulaca oleracea L., its structure was elucidated using NMR and UHPLC-ESI-Q-TOF/MS spectroscopic methods, and presented anti-inflammatory activity at 5 μM.

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The Metabolism Study of Oleraisoquinoline in Rats Using Ultrahigh- performance Liquid Chromatography-electrospray Coupled with Quadrupole Time-of-flight Mass Spectrometry and its Bioactivities

Peishan Liu, Rui Sun, Jiayin Tian, Fan He et autres

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Two new ester alkaloids from Portulaca oleracea L. and their bioactivities

Jiayin Tian, Mingbo Zhang, Yingdai Zhao, Chaoshen Zhang et autres

Two new ester alkaloids were isolated from Portulaca oleracea L., identified as (5-aminofuran-2-yl) methyl acetate (1) named oleracone N and 4(S)-ethyl 3-acetamido-3-(dihydroxyamino) propanoate (2) named oleracone O. The structures were elucidated via spectroscopic methods, including 1 D and 2 D NMR, UHPLC-ESI-QTOF/MS …

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A Novel Amide Alkaloid from Portulaca oleracea

Xiujuan Lan, Shengnan Guo, Mingyang Song, Peishan Liu et autres

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A new alkaloid and two organic acids from Portulaca oleracea L. and their bioactivities

Peishan Liu, Xiujuan Lan, Xiaojun Tao, Jiayin Tian et autres

A new alkaloid, identified as 1-benzyl-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6,7-diol, named oleraisoquinoline (1), and five organic acids and two esters, identified as 5-(hydroxymethyl)furan-2-carboxylic acid (2), 1H-pyrrole-2,5-dicarboxylic acid (3), (7E,10E)-octadeca-7,10-dienoic acid (4), (10E,13E)-octadeca-10,13-dienoic acid (5), (7E,10E)-hexadeca-7,10-dienoic acid (6), methyl tridecanoate (7) and methyl (9E,12E)-octadeca-9,12-dienoate (8), were isolated …

cn, fr (code pays fourni par la source)

Two new lignans with their biological activities in L

Chengyu Wang, Shengnan Guo, Jiayin Tian, Peishan Liu et autres

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