Pia R. Mendoza

Targeting the VIP-VPAC Pathway in Melanoma Models Inhibits Tumor Growth and Liver Metastasis

Wenxi Wang, Hua Yang, Tenzin Passang, Yiwen Helen Li et autres

Uveal melanoma (UVM) is resistant to immune checkpoint therapy and chemotherapy, resulting in high mortality rates, primarily due to liver metastases. While vasoactive intestinal peptide (VIP) signaling has been identified as an immune checkpoint and therapeutic target in pancreatic cancer, its role …

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185 What's the MTRR? A rare cause of deep vein thrombosis and B12 deficiency

Jeffrey Jasper, Ana Camila Michelletti, Christian Mehler, Pia R. Mendoza

Absence of lenadogene nolparvovec DNA in a brain tumor biopsy from a patient in the REVERSE clinical study, a case report

Nancy J. Newman, Matthew Schniederjan, Pia R. Mendoza, David John Calkins et autres

BACKGROUND: Leber Hereditary Optic Neuropathy (LHON) is a rare, maternally-inherited mitochondrial disease that primarily affects retinal ganglion cells (RGCs) and their axons in the optic nerve, leading to irreversible, bilateral severe vision loss. Lenadogene nolparvovec gene therapy was developed as a treatment …

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Clinical and radiographic characteristics of diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma: a single institution review

Dayton P. Grogan, David Painton Bray, Megan Cosgrove, Andrew B. Boucher et autres

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Pathology of the Uveal Tract: Neoplasms

Pia R. Mendoza, Hans E. Grossniklaus

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Gain of Chromosome 6p Correlates with Severe Anaplasia, Cellular Hyperchromasia, and Extraocular Spread of Retinoblastoma

Gustav Stålhammar, Aaron Ming-Hon Yeung, Pia R. Mendoza, Sander R. Dubovy et autres

Purpose Gain of chromosome 6p has been associated with poor ocular survival in retinoblastoma and histopathologic grading of anaplasia with increased risk of metastatic spread and death. This study examined the correlation between these factors and other chromosomal abnormalities as well as …

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Functioning Crooke Cell Adenomas: Case Series and Literature Review

Erica Alexandra Giraldi, Stewart G. Neill, Pia R. Mendoza, Amit M. Saindane et autres

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Abstract #1000208: Crooke Cell Adenomas in Patients with Cushing’s Disease: A Tertiary Care Center Experience

Erica Alexandra Giraldi, Stewart G. Neill, Pia R. Mendoza, Nelson M. Oyesiku et autres

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Pediatric High-Grade Glioma Patterns of Failure by Molecular Subgroup

Lisa Jane Sudmeier, Tiffany Morgan, Pia R. Mendoza, Jeffrey M. Switchenko et autres

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Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma of the Orbit: Three Cases and Review of the Literature

Julia Y. Kang, Hee Joon Kim, Ted H. Wojno, Aaron Ming-Hon Yeung et autres

The authors present 3 patients from this retrospective case series to review the clinical findings, imaging, pathology, and treatment of orbital atypical lipomatous tumor/well-differentiated liposarcoma. Pathology of biopsy specimens ranged from spindle cell proliferations mimicking neurofibroma to proliferations of well-differentiated adipocytes. Immunohistochemical …

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High-Grade Sarcoma Arising within a Previously Irradiated Vestibular Schwannoma: A Case Report and Literature Review

Andrew B. Boucher, Pia R. Mendoza, Stewart G. Neill, Bree Ruppert Eaton et autres

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Morphometric Analysis of Anaplasia in Retinoblastoma

Aaron Ming-Hon Yeung, Hans E. Grossniklaus, Pia R. Mendoza, Robert D'Lorm et autres

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