Accès ouvert
2026
review
OpenAlex
Ana Maria Koller, Maria Oana Săsăran, Ancuța Lupu, Cristina Oana Mărginean
Background Small intestinal bacterial overgrowth (SIBO) and intestinal methanogen overgrowth (IMO) are heterogeneous conditions with poorly standardized antibiotic treatment. This review assessed clinical and test-based outcomes of SIBO therapy, phenotype-specific response, recurrence, and pediatric evidence on the same subject. Methods PubMed/MEDLINE, Scopus, …
ro
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Accès ouvert
2026
article
OpenAlex
Elena Jechel, Ingrith Miron, Cristina Gavrilovici, Iuliana Magdalena Stârcea et autres
Background: Pediatric idiopathic nephrotic syndrome (INS) involves complex immunological mechanisms, and clinical presentation may be influenced by environmental factors and access to medical services. The impact of the COVID-19 pandemic on its clinical and evolutionary profile remains insufficiently characterized. Objectives: To compare …
ro
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Accès ouvert
2026
article
OpenAlex
Alina-Maria Ivaşko, Maria Oana Săsăran, Monica Grama, Teodora Nicola-Varo et autres
Objectives. The diagnosis of food allergy requires, beyond documented serum sensitization, the presence of reproducible symptoms triggered by the implicated allergen. We report the case of a polysensitized child to illustrate the diagnostic approach used to distinguish clinically relevant sensitizations from those …
ro
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Accès ouvert
2026
article
OpenAlex
Ana Stan Muntean, Maria Oana Săsăran, Mihaela Ioana Chinceşan, Andreea Ligia Dinca et autres
Introduction. Burkitt lymphoma is a highly aggressive mature B-cell non-Hodgkin lymphoma that frequently involves abdominal structures in children and may mimic common gastrointestinal or surgical conditions. Objective. To highlight the diagnostic challenges of abdominal Burkitt lymphoma presenting as intermittent intussusception in a …
ro
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Accès ouvert
2026
article
OpenAlex
Ana Stan Muntean, Maria Oana Săsăran, Monica Grama, Andreea Bianca Stoica et autres
Introduction. Human parechovirus (HPeV) is an increasingly recognized cause of sepsis-like illness and central nervous system infection in neonates. The clinical presentation is often nonspecific and may mimic bacterial sepsis, making early diagnosis challenging. Case presentation. We report the case of a …
ro
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Accès ouvert
2026
article
OpenAlex
Maria Oana Săsăran, Claudia BÄnescu
Background and objective Polymorphisms of the vitamin D receptor (VDR) gene have been studied in relation to various diseases, including infections. This narrative review aims to summarize the role of VDR polymorphisms in the susceptibility towards pediatric infectious diseases, as well as …
ro
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Accès ouvert
2026
article
OpenAlex
Maria Oana Săsăran, Monica Grama, Cristina Roxana Mareș, Andreea Bianca Stoica et autres
Introduction: Hypocalcemia represents a major cause of seizures in children in the absence of fever or infections. Hypovitaminosis D, usually associated with a lack of proper prophylactic regimens, can trigger those events. This case series aims to highlight two cases of hypocalcemic …
ro
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Accès ouvert
2026
article
OpenAlex
Cristina Oana Mărginean, Maria Oana Săsăran
It is an honor and a privilege to have helped edit and bring this Special Issue titled "Nutrition in Children's Growth and Development" to you [...].
ro
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Accès ouvert
2026
article
OpenAlex
Maria-Andreea Răcean, Maria Oana Săsăran, Adina Huţanu, Manuela Cucerea et autres
Early-onset neonatal sepsis (EONS) remains a challenging diagnosis in clinical practice, with limited available paraclinical data. This study aims to analyze the utility of two cytokines determined from the umbilical cord blood (UCB) of newborns and from maternal blood, IL-6 and IL-8, …
ro
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Accès ouvert
2026
article
OpenAlex
Ancuţa Ignat, Emil Anton, Maria Oana Săsăran, Irina Tarnita et autres
Type 1 Diabetes (T1D) is a complex autoimmune disorder characterized by immune-mediated destruction of pancreatic β cells, driven by genetic susceptibility and modulated by environmental factors, notably the gut microbiome. Dysbiosis, manifested as reduced microbial diversity, perturbations in the Firmicutes/Bacteroidetes ratio, and …
ro
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Accès ouvert
2026
review
OpenAlex
Vasile Valeriu Lupu, Alin Horațiu Nedelcu, Ingrith Miron, Sorana Caterina Anton et autres
Neurodevelopment is a dynamic and multifactorial process, critical in the early stages of life, involving the formation of neural networks, the establishment of synapses, and the maturation of cognitive, social and emotional circuits. In this context, the gut microbiome emerges as an …
ro
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Accès ouvert
2026
article
OpenAlex
Carmen Corina Şuteu, Nicola Șuteu, Liliana Gozar, Oana Cristina Marginean et autres
Background: Neonatal Ebstein’s anomaly (EA) is a severe condition with significant hemodynamic instability and early myocardial dysfunction, where abnormal right-heart geometry limits conventional echocardiography and highlights the value of myocardial deformation imaging. Methods: We conducted a single-center retrospective observational study including 16 …
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