A. N. Zvyagintseva

Savelyeva LV. Isolated hypogonadotropic hypogonadism caused by a mutation in the WDR11 gene: a clinical case report

Daria V. Ivanova, A. N. Zvyagintseva, Е. В. Морозова, С. И. Моткова et autres

Isolated hypogonadotropic hypogonadism is a heterogeneous group of rare hereditary disorders characterized by impaired gonadotropin secretion, leading to delayed or absent puberty, reduced fertility, and infertility. In recent years, significant progress has been achieved in understanding the molecular genetic mechanisms underlying hypogonadotropic …

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Type 1 diabetes mellitus in combination with granulomatosis with polyangiitis: a clinical case report

A. N. Zvyagintseva, Д. В. Иванова, S. V. Sergeeva, A. Y. Tokmakova et autres

We report a rare clinical case of the coexistence of two autoimmune diseases: type 1 diabetes mellitus and granulomatosis with polyangiitis. Both conditions share a common target — small-caliber blood vessels — which contributes to overlapping mechanisms of tissue injury, progressive microcirculatory …

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Repeat kidney transplantation in a patient with type 1 diabetes mellitus and chronic pyelonephritis: a clinical case

A. N. Zvyagintseva, Daria V. Ivanova, А. С. Северина, Минара Шамхаловна Шамхалова

Cadaveric kidney allotransplantation remains the most effective and safest therapeutic option for end-stage renal disease in patients with diabetes mellitus. Successful graft survival requires consideration of multiple factors that may contribute to transplant injury. Particular emphasis should be placed on minimizing the …

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Influence of diabetes mellitus on the results of providing assistance in critical lower limb ischemia

Н. И. Глушков, A. N. Zvyagintseva, P. D. Puzdriak, A.V. Milkova et autres

Introduction . The elimination of critical ischemia in patients with diabetes mellitus requires a delicate approach due to the high risk of complications. The purpose of this study is to analyze the results of revascularization in patients with critical ischemia associated with …

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To the question of thrombotic and hemorrhagic complications in patients with COVID-19

Н. И. Глушков, P. D. Puzdriak, A. N. Zvyagintseva, E. I. Panasyuk et autres

COVID-19 is characterized by various adverse consequences and complications, the prevention of which affects the outcome of the disease. Aim of the study was to investigate the thrombohemorrhagic events of COVID-19 infection. Material and methods. This study involved 403 patients with novel …

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Is reconstruction justified at the claudication stage in a patient with peripheral atherosclerosis?

Н. И. Глушков, A. N. Zvyagintseva, Yu.A. Horeva, Aknur Atayeva et autres

Rationale: The possibility of surgical intervention in patients with claudication determines the direction of treatment. At the same time, some patients are not characterized by a benign course of peripheral arterial disease. This work is based on clarifying the results of reconstructive …

Thrombotic and hemorrhagic complications in COVID-19.

Н. И. Глушков, P. D. Puzdriak, A. N. Zvyagintseva, E. I. Panasyuk et autres

Background. In some cases, a new coronavirus infection demonstrates non-standard clinical manifestations, an integral characteristic of which is a tendency to thrombotic and hemorrhagic complication. Objective. To study the predisposing factors for the development of thrombotic and hemorrhagic complications in patients with …

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