Thomas Matthew Habermann

Improved overall survival in classical Hodgkin lymphoma across therapeutic eras: A National Cancer Database study

Julia Wang, Yajuan Gao, Spears M. Grant, Steven Ray Hwang et autres

This study used data from the National Cancer Database (NCDB), a hospital-based, de-identified oncology registry jointly sponsored by the American College of Surgeons and the Commission on Cancer. The NCDB data are available to qualified investigators through an application process and Institutional …

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Perinatal and Early-Life Exposures and Risk of Non-Hodgkin Lymphoma

George A. Cholack, Geffen Kleinstern, Dennis P. Robinson, Carrie A. Thompson et autres

Background: Perinatal and early-life factors may influence non-Hodgkin lymphoma (NHL) risk, but study results have been mixed and exposure data for childhood ages are limited. Herein, we investigated associations of these exposures with risk of NHL and common subtypes. Methods: This case–control …

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Malignant B-cell States Orchestrate Spatially Organized Immune Ecosystems in B-cell Lymphomas

Patrizia Mondello, Alisa Sadekova, ksenia fede, Surendra Dasari et autres

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ABCL-729: Epstein-Barr Virus–Positive Sinonasal Plasma Cell Neoplasms: A Case Series With Favorable Outcomes in Older Men

Izel Okcu, Husam A. Jum’ah, Patrick B. Johnston, David James Inwards et autres

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POSTER: ABCL-729: Epstein-Barr Virus–Positive Sinonasal Plasma Cell Neoplasms: A Case Series With Favorable Outcomes in Older Men

Izel Okcu, Husam A. Jum’ah, Patrick B. Johnston, David James Inwards et autres

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Meta-Analysis of Genome-Wide Association Studies of Doxorubicin-Induced Arrhythmia Identifies MMP16 and KCTD15 as Risk Loci

Joseph S. Reddy, Milagros Pereyra, Mohammed Tiseer Abbas, Reza Arsanjani et autres

BACKGROUND: Anthracyclines are a widely used and effective class of chemotherapy. However, a major limitation for their use is cardiotoxicity, manifesting as systolic dysfunction, congestive heart failure, and arrhythmias. The objective of this study was to identify genes and genetic risk variants …

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Treatment patterns and outcomes for second-line therapy in large B-cell lymphoma: results from the LEO CReWE study

Jean Louise Koff, Melissa C. Larson, Jonathon B. Cohen, Izidore S. Lossos et autres

Abstract Treatment strategies for relapsed/refractory large B-cell lymphoma (R/R LBCL) have evolved rapidly, yet relationships between therapy selection and outcomes remain poorly defined. The LEO CReWE study evaluated disease characteristics, patterns of care, and outcomes in 1504 patients with R/R LBCL from …

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No Association of Prior Administration of Selected Vaccines with Lymphoma Prognosis

George A. Cholack, Verena Hinder, Raphael Mwangi, Thomas Matthew Habermann et autres

BACKGROUND: Although some vaccines seem to be associated with a lower risk of lymphoma, their impact on outcomes is largely unknown. METHODS: Data from a large prospective lymphoma cohort study were utilized to estimate associations of self-reported history of vaccination against hepatitis …

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Immunity Gone Viral

Sonali Ajwani, Brian G. Weinshenker, Caterina Giannini, Thomas Matthew Habermann et autres

Subacute cognitive decline and imbalance in aquaporin-4-antibody-seropositive neuromyelitis optica spectrum disorder (AQP4+NMOSD) treated with mycophenolate has a broad differential diagnosis, including cerebral involvement of AQP4+NMOSD, infections, or other complications of immunosuppression. In this article, we highlight the diagnostic and treatment approach in …

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Figure 5 from MRI Deep Learning for Differentiating Glioblastoma, IDH Wild-type from Central Nervous System Diffuse Large B-cell Lymphoma

Mana Moassefi, Paul A. Decker, Gian Marco Conte, Matthew Kosel et autres

Violin plots showing the model scores for the 256 GBM and 73 CNS-DLBCL cases in stage 3, obtained from the models developed using the (A) ensemble approach and (B) loss approach.

Figure 3 from MRI Deep Learning for Differentiating Glioblastoma, IDH Wild-type from Central Nervous System Diffuse Large B-cell Lymphoma

Mana Moassefi, Paul A. Decker, Gian Marco Conte, Matthew Kosel et autres

Description of the three-stage study design.

Supplementary Figure S1 from MRI Deep Learning for Differentiating Glioblastoma, IDH Wild-type from Central Nervous System Diffuse Large B-cell Lymphoma

Mana Moassefi, Paul A. Decker, Gian Marco Conte, Matthew Kosel et autres

Cartoon comparing AUC and cross entropy loss on five GBM patients and five CNS-DLBCL cases. Grey denotes GBM and black denotes CNS-DLBCL. All models have the same AUC (AUC=100%); however, Model 4 has the smallest cross entropy loss.