Olesya L. Ilkun

Emerging treatments and current strategies for mineral, vascular, and bone disorders in chronic kidney disease

Olesya L. Ilkun, Firouzeh Jazayeri, Amir Kazory

Progressive loss of kidney function in chronic kidney disease and end-stage kidney disease leads to distinct pathological changes in mineral and bone metabolism. Historically, the management of these patients focused on lowering their serum phosphate, parathyroid hormone, and normalizing serum calcium. However, …

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Effect of Whey and Soy Protein Supplements on Inflammation in Adults on Chronic Hemodialysis: A Double-blind Randomized Crossover Controlled Study

Danielle Francesca Aycart, Sofía Acevedo, Olesya L. Ilkun, Firouzeh Jazayeri et autres

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When Monoclonality Meets Crescents: A Case of Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits with Rapidly Progressive Glomerulonephritis

Htun H. Naing, William L. Clapp, Olesya L. Ilkun

Introduction: Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is a rare glomerulonephritis caused by deposition of a monoclonal immunoglobulin within the glomeruli. The triggers and management for PGNMID are incompletely understood, particularly when associated with rapidly progressive glomerulonephritis (RPGN). Case Description: A …

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Breaking barriers: Neprilysin inhibition in chronic cardiorenal syndrome

Olesya L. Ilkun, Amir Kazory

Over the last decade, neprilysin inhibition has been established as the cornerstone of therapy in heart failure (HF). Patients with chronic kidney disease (CKD) and end-stage kidney disease (ESKD) have a high prevalence of HF; the concomitant presence of HF and CKD …

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Liquid Silicone Injections: An Infrequent Cause of CKD and Kidney Stones

Ivette Gomez, Anu Sharma, Olesya L. Ilkun

Introduction: The use of body-modifying cosmetic injections have increased over the last decades. Here we present an infrequent case of severe kidney-related complications due to hypercalcemia arising years after silicone injections. Case Description: A 44-year-old man with stage 4 chronic kidney disease …

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Uremic Leontiasis Ossea due to Resistant Secondary Hyperparathyroidism

Kubra Melek Tuna, Olesya L. Ilkun, Peter T. Dziegielewski, Anu Rani Sharma

Background/Objective: Severe progressive overgrowth of the facial bones known as uremic leontiasis ossea (ULO) is a rare complication of resistant hyperparathyroidism in end-stage renal disease (ESRD). The objective of this report is to describe the presentation and treatment of ULO. Case Report: …

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Bilateral Hydronephrosis due to Rosai-Dorfman Disease

Olesya L. Ilkun, Rama Kethineni, Monique E. Cho, Josephine D. Abraham

Introduction: Rosai-Dorfman Disease (RDD) is a rare histiocytic proliferative disorder, with approximately 100 cases diagnosed each year in the United States. Typically it presents as nodal and cutaneous disease, but kidneys can be affected in 4% of cases. Case Description: We present …

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Anti-Glomerular Basement Membrane Disease Sans Kidney Involvement

Olesya L. Ilkun, Josephine D. Abraham

Introduction: Anti-Glomerular Basement Membrane (anti-GBM) is an autoimmune disease involving glomerular and pulmonary capillaries diagnosed in 1 patient per million per year. Predominant lung involvement can be seen in 6% of patients most of which still demonstrate microscopic hematuria and biopsy with …

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Bilateral Pyomyositis in a Kidney Transplant Patient

Olesya L. Ilkun, Divya Raghavan, Fuad S. Shihab, Josephine D. Abraham

Introduction: Immunocompromised hosts are susceptible to infectious complications including pyomyositis, a purulent bacterial infection of deep skeletal muscle that most commonly affects lower extremities (LE) and is acquired through hematogenous spread, trauma or injections. Case Description: A 30-year-old man who received a …

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Severe Hypercalcemia in a Patient with Acute Lobar Nephronia

Olesya L. Ilkun, Martin C. Gregory, Monique E. Cho, Josephine D. Abraham

Introduction: Acute lobar nephronia is a form of focal acute bacterial pyelonephritis without abscess formation or liquefaction. Case Description: A 62-year-old Native American woman with a childhood history of left nephrectomy and treatment for tuberculosis was admitted for sepsis due to pyelonephritis …

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Black Tar Heroin and AA Amyloidosis

Rama Kethineni, Monique E. Cho, Monica P. Revelo Penafiel, Olesya L. Ilkun et autres

Introduction: AA amyloidosis due to deposition of serum amyloid A protein occurs as a secondary reaction to chronic inflammatory disease, chronic infections, and familial period fever syndromes. We present a case of AA amyloidosis secondary to chronic black tar Heroin use in …

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Discrepancies in automated, electronic medical record-based CHA2DS2-VASc scores and clinician assessment for atrial fibrillation patients

Aubrey E. Jones, Zameer Abedin, Olesya L. Ilkun, Rebeka Mukherjee et autres

Abstract Background Clinical decision support tools for atrial fibrillation (AF) should include CHA 2 DS 2 - VASc scores to guide oral anticoagulant (OAC) treatment. Objective We compared automated, electronic medical record (EMR) generated CHA 2 DS 2 - VASc scores to …

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