Shanna M. Hogeling

Multi‑omics factor analysis reveals a RAS mutant-like metabolically distinct AML subgroup resistant to venetoclax

Jan Jacob Schuringa, Dominique Sternadt, Shanna M. Hogeling, Lieve Oudejans et autres

nl (code pays fourni par la source)

Sustained PRC1.1 activity preserves gene repression independently of PRC2.2 and restrains leukemic cell differentiation

Fatemeh Mojallali, Alessandra De Meis, Sinne Alkema, Tjerk Jan Atsma et autres

nl (code pays fourni par la source)

ΔNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemia

Diego A. Pereira-Martins, Cesar Ortiz, Isabel Weinhäuser, Albertus T.J. Wierenga et autres

br, nl, gb (code pays fourni par la source)

Potent synergy of DHODH and SREBP inhibition in acute myeloid leukemia via disruption of cholesterol and lipid metabolism

Shanna M. Hogeling, Dominique Sternadt, Nikita La Rose, Marjan Geugien et autres

nl, be, us (code pays fourni par la source)

3046 – SUSTAINED PRC1.1 ACTIVITY PRESERVES GENE REPRESSION INDEPENDENT OF PRC2.2 AND SUPPRESSES LEUKEMIC CELL DIFFERENTIATION

Vincent van den Boom, Fatemeh Mojallali, Tjerk Jan Atsma, Alessandra De Meis et autres

Metformin induces ferroptosis associated with lipidomic remodeling in AML

Dominique Sternadt, Diego A. Pereira‐Martins, Prodromos Chatzikyriakou, Luise Albuquerque-Simões et autres

nl, gb, br, de, fr (code pays fourni par la source)

The identification of novel therapeutic targets in acute myeloid leukemia

Shanna M. Hogeling

ΔNp73 Isoform Defines a New TP53mutant-Like Poor Risk Subgroup of Acute Myeloid Leukemia

Diego A. Pereira‐Martins, César Alexander Ortiz Rojas, Isabel Weinhäuser, Albertus T.J. Wierenga et autres

nl, br, gb (code pays fourni par la source)

Bleximenib, the novel menin-KMT2A inhibitor JNJ-75276617, impairs long-term proliferation and immune evasion in acute myeloid leukemia

Shanna M. Hogeling, Duy Minh Lê, Nikita La Rose, Min Chul Kwon et autres

nl, be (code pays fourni par la source)

DGAT1 Inhibition Enhances Metformin-Induced Ferroptosis in AML By Targeting Lipid Metabolism

Dominique Sternadt, Diego A. Pereira‐Martins, Douglas RA Silveira, Isabel Weinhaeuser et autres

nl, gb, de, be (code pays fourni par la source)

Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A - and NPM1 -altered leukemias

Min Chul Kwon, Jan Willem Thuring, Olivier Querolle, Xuedong Dai et autres

be, us, nl (code pays fourni par la source)

M2 macrophages drive leukemic transformation by imposing resistance to phagocytosis and improving mitochondrial metabolism

Isabel Weinhäuser, Diego A. Pereira‐Martins, Luciana Yamamoto Almeida, Jacobien R. Hilberink et autres

nl, br, gb (code pays fourni par la source)