Accès ouvert
2025
article
OpenAlex
Samin Mohsenian, Roberta Palla, Marzia Menegatti, Andrea Cairo et autres
Background: Women and girls with congenital fibrinogen deficiencies (CFDs) face higher hemorrhagic risks during their reproductive years, yet data on gynecologic and obstetric complications remain limited. Objectives: We aimed to rate the prevalence of heavy menstrual bleeding and obstetric complications in women …
it, ch, ae, ir, gr, nl, us, gb
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Accès ouvert
2024
article
OpenAlex
Samin Mohsenian, Roberta Palla, Marzia Menegatti, Andrea Cairo et autres
ABSTRACT: Congenital fibrinogen deficiency (CFD) is a rare bleeding disorder caused by mutations in FGA, FGB, and FGG. We sought to comprehensively characterize patients with CFD using PRO-RBDD (Prospective Rare Bleeding Disorders Database). Clinical phenotypes, laboratory, and genetic features were investigated using …
it, ch, cz, fr, gr, nl, pk, tr, gb, us
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Accès ouvert
2023
article
OpenAlex
Dusica Basaric, Marko Saracevic, Vesna Bosnic, Anka Vlatkovic et autres
OBJECTIVE: Elevated factor VIII has been shown to be an independent risk factor for deep venous thrombosis and pulmonary embolism. It has been suggested that increased factor VIII levels by itself is insufficient to cause thrombosis; however, increased factor VIII with other …
hr, rs, ru
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2016
article
OpenAlex
Roberta Palla, Marzia Menegatti, Marco Boscarino, Jan Blatný et autres
Abstract BACKGROUND: Congenital fibrinogen disorders are rare diseases affecting either the quantity (afibrinogenaemia and hypofibrinogenaemia) or the quality (dysfibrinogenaemia) or both (hypodysfibrinogenaemia) of fibrinogen. Afibrinogenemia is associated with mild-to-severe bleeding, whereas hypofibrinogenemia is most often asymptomatic. Previously, our group (Peyvandi et al, …
it, cz, fr, gr, nl, pk, ch, tr, gb, us
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2014
article
OpenAlex
Flora Peyvandi, Marzia Menegatti, Roberta Palla, Simona Maria Siboni et autres
Abstract The PRO-RBDD is a prospective study of fibrinogen and FXIII deficiency designed to collect data on demographics, laboratory phenotype, genotype, clinical manifestations, obstetric data, surgery, treatment type and its efficacy and safety. Central laboratory testing is also available for diagnosis confirmation …
it, pk, gr, nl, us, ch, tr, gb, ir, fr
(code pays fourni par la source)