Ruairidh Macleod

Prehistoric plague could have caused population collapse in stone age Europe

Ruairidh Macleod, Stephen Shennan

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Lethal plague outbreaks in Lake Baikal hunter-gatherers 5,500 years ago

Ruairidh Macleod, Frederik Valeur Seersholm, Bianca De Sanctis, Angela R. Lieverse et autres

Abstract Plague is among the most devastating diseases in human history 1 . However, early strains of the plague-causing bacterium Yersinia pestis lacked virulence factors that are required for the bubonic form until around 3,800 years ago 2,3 . Consequently, the morbidity …

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Bamdam: a post-mapping authentication toolkit for ancient metagenomics

Bianca De Sanctis, Cade Mirchandani, Haoran Dong, Ruairidh Macleod et autres

Ancient metagenomic studies using capture or shotgun sequencing often perform pairwise alignment of individual reads against large reference databases followed by lowest common ancestor assignment for taxonomic identification. Here, we present bamdam, a lightweight post-mapping, post lowest common ancestor toolkit for eukaryotic …

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Environmental DNA Reveals Reykjavík’s Human and Ecological History

Kurt H. Kjær, Anthony Ruter, Mateu Menéndez‐Serra, Nicola Alexandra Vogel et autres

Summary Iceland was among the last large islands settled by humans, with colonization (Landnám) in the late 9th century CE (Common Era) and is often portrayed as an ecological disaster driven by the Norse settlers. Here, we revisit this narrative through environmental …

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TBH1: 12 000-year-old human skeleton and projectile point shed light on demographics and mortality in Terminal Pleistocene Southeast Asia

Christopher Stimpson, Alex Wilshaw, Benjamin Utting, Nguyen Thi Mai Huong et autres

The paucity of well-preserved and dated Pleistocene human remains impedes investigation of demographics and interactions in Late Pleistocene populations in Southeast Asia. Here, we report TBH1, an exceptionally well-preserved approximately 35-year-old male skeleton dated 12 500-12 000 years before present that provides …

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Author response for "TBH1: 12 000-year-old human skeleton and projectile point shed light on demographics and mortality in Terminal Pleistocene Southeast Asia"

Christopher Stimpson, Alex Wilshaw, Benjamin Utting, Nguyễn Thị Mai Hương et autres

Hiding in plain sight: the biomolecular identification of pinniped use in medieval manuscripts

Élodie Lévêque, Matthew D. Teasdale, Sarah Fiddyment, Maiken Hemme Bro‐Jørgensen et autres

The survival of medieval manuscripts in their original bindings remains a rare occurrence. Taking advantage of the diversity of bindings in Cistercian libraries such as Clairvaux and its daughter abbeys during the twelfth and thirteenth centuries, this study focuses on the biocodicological …

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Author response for "Hiding in plain sight: the biomolecular identification of pinniped use in medieval manuscripts"

Élodie Lévêque, Matthew D. Teasdale, Sarah Fiddyment, Maiken Hemme Bro‐Jørgensen et autres

North Pontic crossroads: Mobility in Ukraine from the Bronze Age to the early modern period

Lehti Saag, Olga Utevska, Stanislav Zadnikov, Iryna Shramko et autres

The North Pontic region, which encompasses present-day Ukraine, was a crossroads of migration, connecting the vast Eurasian Steppe with Central Europe. We generated shotgun-sequenced genomic data for 91 individuals dating from around 7000 BCE to 1800 CE to study migration and mobility …

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The Mesolithic Hunter–Gatherer Camp Site at Sammakko in Norrbotten, Northernmost Sweden—Archeological Finds and Palaeoenvironmental Reconstruction

Per Möller, Frida Palmbo, Anne Birgitte Nielsen, Emma Boman et autres

ABSTRACT A small Mesolithic camp site near Sammakko in northernmost Sweden has been identified through its abundance of burnt bone and quartz refuse from stone tool manufacturing/maintenance. Radiocarbon dating places hunter–gatherer activity here around 8900 years ago, 1800 years later than the …

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Benchmarking the identification of a single degraded protein to explore optimal search strategies for ancient proteins

Ismael Rodríguez Palomo, Bharath Nair, Yun Chiang, Joannes Dekker et autres

Palaeoproteomics is a rapidly evolving discipline, and practitioners are constantly developing novel strategies for the analyses and interpretations of complex, degraded protein mixtures. The community has also established standards of good practice to interrogate our data. However, there is a lack of …

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eProbe : a capture probe design toolkit for genetic diversity reconstructions from ancient environmental DNA

Zihao Huang, Zhengquan Gu, Yuanyang Cai, Ruairidh Macleod et autres

Abstract Ancient environmental DNA (aeDNA) is now commonly used in paleoecology and evolutionary ecology, yet due to difficulties in gaining sufficient genome coverage on individual species from metagenome data, its genetic perspectives remain largely uninvestigated. Hybridization capture has proven as an effective …

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