Kathy Green

Depletion of monocytic myeloid-derived suppressor cells in LP-BM5 murine retroviral infection has a positive impact on virus-induced host immunodeficiency

Kathy Green, Chi Ma, FuKun W. Hoffmann, Peter Hoffmann et autres

We have shown the induction of CD11b + Ly6C + monocytic myeloid-derived suppressor cells (M-MDSCs) during infection of B6 mice by LP-BM5 immunodeficiency-inducing retrovirus. We published that the molecular mechanisms of these M-MDSCs vary, and depend on the cell type targeted by …

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Upregulated selenoprotein I during lipopolysaccharide-induced B cell activation promotes lipidomic changes and is required for effective differentiation into IgM-secreting plasma B cells

Chi Ma, FuKun W. Hoffmann, Ashley E. Shay, Imhoi Koo et autres

The mechanisms driving metabolic reprogramming during B cell activation are unclear, particularly roles for enzymatic pathways involved in lipid remodeling. We found that murine B cell activation with lipopolysaccharide (LPS) led to a 1.6-fold increase in total lipids that included higher levels …

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Inhibition of myeloid-derived suppressor cell (MDSC) activity by redox-modulating agents restores T and B cell proliferative responses in murine AIDS

Alessandra Fraternale, Kathy Green, Giuditta Fiorella Schiavano, Michela Bruschi et autres

The mechanisms by which myeloid-derived suppressor cells (MDSCs) mediate inhibition prominently include the production of reactive nitrogen species, in particular those generated by inducible nitric oxide synthase (iNOS), and reactive oxygen species. LP-BM5 murine retroviral infection results in a profound immunodeficiency, known …

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A systematic review of exploratory factor analysis packages in R software

Priyalatha Govindasamy, Nor Junainah Mohd Isa, Nor Firdous Mohamed, Amelia Mohd Noor et autres

Abstract The increasing prevalence of exploratory factor analysis (EFA) applications in scholarly literature reflects its popularity and the convenience of computer‐assisted analysis. With advancements in computer hardware and software, the complexity and variations of EFA analysis have also grown. Despite the availability …

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The Royal Berkshire NHS Foundation Trust outpatient services transformation programme to improve quality and effectiveness of patient care

Antoni Chan, Kathy Green, Kiki Kontra, Toby M. Chapman et autres

Background: The Royal Berkshire NHS Foundation Trust outpatient services transformation programme is a strategic change programme delivered as a collaborative approach through the Berkshire West Integrated Care Partnership. The main aim of redesign is to improve capacity in clinics and improve patient …

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A Once in a Lifetime Opportunity to Experience 21st Century Teacher Education

Matthew D. Zbaracki, Kathy Green

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A Comparison of Latent Class Analysis and the Mixture Rasch Model Using 8th Grade Mathematics Data in the Fourth International Mathematics and Science Study (TIMSS-2011)

Türker TOKER, Kathy Green

This study provides a comparison of the results of latent class analysis (LCA) and mixture Rasch model (MRM) analysis using data from the Trends in International Mathematics and Science Study – 2011 (TIMSS-2011) with a focus on the 8th-grade mathematics section. The …

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I-152, a supplier of N-acetyl-cysteine and cysteamine, inhibits immunoglobulin secretion and plasma cell maturation in LP-BM5 murine leukemia retrovirus-infected mice by affecting the unfolded protein response

Alessandra Fraternale, Carolina Zara, Tomas Di Mambro, Elisabetta Manuali et autres

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Tu1939 IS A MULTIVITAMIN SUFFICIENT TO MEET NUTRITIONAL REQUIREMENTS IN CANADIAN ADULTS WITH CELIAC DISEASE FOLLOWING A GLUTEN-FREE DIET?

Richa Chibbar, Dayna Weiten, Kathy Green, Lisa Rigaux et autres

HIF-1α is essential for T cell suppression by murine LP-BM5 retrovirus infection-augmented Monocytic Myeloid Derived Suppressor Cells

Kathy Green, Robert A. Cramer, William R. Green

Abstract Compared to naïve mice, monocytic myeloid-derived suppressor cells (M-MDSCs) increase in number, and suppressive efficiency, after infection with the immunodeficiency causing mouse retrovirus, LP-BM5. In ex vivo suppression assays, M-MDSCs, enriched from spleens of LP-BM5 infected mice inhibited both T- and …

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Implementing the National Heart, Lung, and Blood Institute’s Strategic Vision in the Division of Cardiovascular Sciences

David C. Goff, Denis B. Buxton, Gail D. Pearson, Gina S. Wei et autres

Anniversary of the National Heart, Lung, and Blood Institute (NHLBI) and celebrate important milestones that have been achieved by the Division of Cardiovascular Sciences (DCVS), it is imperative that DCVS and the Extramural Research community at-large continue to address critical public health …

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Rasch Analysis of the Brief Symptom Inventory-18 with African Americans.

Ruth Chao, Kathy Green, Kranti Dugar, Joseph Longo

Although the United States offers some of the most advanced psychological services in the world, not everyone in U.S. shares equally in these services, and health disparities persist when assessments do not appropriately measure different populations' mental health problems. To address this …

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