Yoshinari Asaoka

Stability and Variability of Symptom Burden in Primary Biliary Cholangitis: Insights From a Decade of Follow‐Up

Akihito Takeuchi, Atsumasa Komori, Kazuhito Kawata, Osamu Yoshida et autres

BACKGROUND AND AIMS: Primary biliary cholangitis (PBC) frequently impairs health-related quality of life (HRQOL); however, longitudinal changes in symptoms and their relationship with prognosis remain unclear. We aimed to elucidate the current status of symptoms and HRQOL in Japanese patients with PBC, …

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A machine learning algorithm for optimizing treatment selection for patients with up to three hepatocellular carcinomas measuring ≤ 3 cm.

Takashi Kokudo, Yasuhide Yamada, Yoshinari Asaoka, Ryosuke Tateishi et autres

4019 Background: Liver resection (LR) and radiofrequency ablation (RFA) are recommended for patients with early-stage hepatocellular carcinoma (HCC) with three nodules measuring ≤3 cm and preserved liver function. This study aimed to develop a predictive model to guide treatment decisions based on …

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A machine learning algorithm facilitates treatment selection for up to three hepatocellular carcinomas ≤3 cm in size

Takashi Kokudo, Yasuhide Yamada, Yoshinari Asaoka, Ryosuke Tateishi et autres

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Impact of Chronic Kidney Disease on Gastrointestinal Bleeding in Patients with Non-Valvulvar Atrial Fibrillation

Minoru Oda, takatsugu yamamoto, hitoshi aoyagi, koichiro abe et autres

Active Sequential Treatment Improves the Prognosis after Discontinuing Atezolizumab plus Bevacizumab Therapy for Unresectable Hepatocellular Carcinoma A Retrospective Multicenter Study

Kentaro Takahashi, N. TAKAMURA, Akihito Takeuchi, Kotaro Matsumoto et autres

Association of bile acid composition with synthetic pathways and efficacy of bezafibrate in cholestatic liver disease

Manami Iida, Atsuko Higashida, Shuichi Ohtomo, Akihito Takeuchi et autres

BACKGROUND/AIMS: Bezafibrate (BZF), a dual peroxisome proliferator-activated receptor/pregnane X receptor agonist, has demonstrated efficacy in combination with ursodeoxycholic acid (UDCA) for primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). Although one of the therapeutic effects of BZF is suppression of bile …

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A Newly Launched Nationwide Database Revealed Real-World Evidence on Systemic Therapy for Unresectable Hepatocellular Carcinoma in Japan: Hepatoma Registry of Integrating and Aggregating Electronic Health Record (HERITAGE)

Yoshinari Asaoka, Ryosuke Tateishi, Yasuhide Yamada, Takashi Kokudo et autres

Background and Aims: As systemic therapy for hepatocellular carcinoma (HCC) rapidly advances, eight treatment regimens are currently approved in Japan. However, the limited settings of phase III clinical trials necessitate large-scale real-world data to evaluate effective treatment sequences. To address this, we …

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Predicting the risk of developing diabetes in steatotic liver disease using controlled attenuation parameter in a health checkup population

T. Nakatsuka, Y. Yamaji, Ryosuke Tateishi, Yoshiaki Kawashima et autres

Abstract Introduction Excessive hepatic steatosis is linked to systemic metabolic disorders. We investigated the association between hepatic steatosis quantified by controlled attenuation parameter (CAP) and the development of type 2 diabetes mellitus (T2DM) in a health checkup population. Methods The present retrospective …

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Validation of PBC‐10 in Japanese patients with primary biliary cholangitis

Akihito Takeuchi, Masanori Abe, Sachiko Furukawa, Tadashi Namisaki et autres

BACKGROUND AND AIM: Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease that significantly impairs health-related quality of life (HRQOL). The PBC-10, a short-form HRQOL assessment tool, was developed for rapid screening in clinical settings. This study aimed to verify the …

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Asian Conference on Tumor Ablation Guidelines for Hepatocellular Carcinoma

Shuichiro Shiina, Ryosuke Tateishi, Joon Il Choi, So Yeon Kim et autres

Globally, the incidence and associated mortality of primary liver cancer have been steadily increasing. Currently, 80% of cases are found in Asia. Curative resection is applicable in only 20% of patients; therefore, various nonsurgical treatment modalities have been developed. Image-guided percutaneous liver …

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Retrospective evaluation of a novel ultrasound-based imaging analysis software for predicting radiofrequency ablation areas

Masaya Sato, Ryosuke Tateishi, Jiro Sato, Takeyuki Watadani et autres

OBJECTIVE: This study aimed to introduce and evaluate a novel software-based system, BioTrace, designed for real-time monitoring of thermal ablation tissue damage during image-guided radiofrequency ablation for hepatocellular carcinoma (HCC). METHODS: BioTrace utilizes a proprietary algorithm to analyze the temporo-spatial behavior of …

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[A case of multiple liver tumors detected by abdominal ultrasound during a health check-up].

Yoshinari Asaoka, Atsushi Tanaka

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