Barbara Canepa

Oxysterol-induced oxidative disruption of skin junction integrity

Alessandra Pecorelli, Anna Guiotto, Alice Casoni, Marta Ruzza et autres

The cutaneous tissue is persistently exposed to environmental stressors, including a wide range of airborne pollutants. This chronic exposure often leads to a condition of oxidative stress, with the outermost layer of epidermis, the stratum corneum (SC), being especially vulnerable due to …

it, us (code pays fourni par la source)

Skin barrier protein responses to oxysterol exposure: from diet to outdoor stressors

Alessandra Pecorelli, Alice Casoni, Anna Guiotto, Marta Ruzza et autres

us, it, kr (code pays fourni par la source)

Development of a New Indirect ELISA Test for the Detection of Anti-Feline Coronavirus Antibodies in Cats

Irene Ferrero, Sarah Dewilde, Barbara Canepa, Enrica Giachino et autres

BACKGROUND/OBJECTIVES: Feline coronavirus (FCoV) belongs to the family Coronaviridae and includes two pathotypes, the less virulent feline enteric coronavirus (FECV), which replicates in the enteric epithelial cells, and feline infectious peritonitis virus (FIPV), which is more virulent, replicates efficiently within monocytes/macrophages with …

it (code pays fourni par la source)

Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety

Stefano Sainas, Marta Giorgis, Paola Circosta, Giulio Poli et autres

has an extremely low cytotoxicity on non-AML cells as well as MEDS433; it has shown a significant antileukemic activity in vivo in a xenograft mouse model of AML.

it, se (code pays fourni par la source)

Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Biphenyl Moiety

Stefano Sainas, Marta Giorgis, Paola Circosta, Valentina Gaidano et autres

(Jurkat) > 100 μM).

it, cn, se (code pays fourni par la source)

1H-NMR and MALDI-TOF MS as metabolomic quality control tests to classify platelet derived medium additives for GMP compliant cell expansion procedures

Francesco Agostini, Marta Ruzza, Davide Corpillo, Luca Biondi et autres

INTRODUCTION: Ex vivo cell expansion under Good Manufacturing Practice (GMP) guidelines can be performed using medium additives containing human growth factors from platelets. These products can differently affect proliferation of adipose mesenchymal stromal stem cells (ASC). Qualification of medium additive performance is …

it (code pays fourni par la source)

The activity of aminoacyl‐tRNA synthetase‐interacting multi‐functional protein 1 (AIMP1) on endothelial cells is mediated by the assembly of a cytoskeletal protein complex

Valentina Charlotte Jackson, Sarah Dewilde, Alessandra Giuliano Albo, Katarzyna Lis et autres

AIMP1 was first found as a factor associated with the aminoacyl-tRNA synthetase (ARS) complex. However, it is also secreted and acts on different target cells such as endothelial cells, macrophages, and fibroblasts as an extracellular regulator, respectively, of angiogenesis, inflammatory responses and …

Study of Glial Fibrillary Acidic Protein activity when released by Glioblastoma Multiforme

N. Minari, R. Reviglione, Davide Corpillo, Alessandra Giuliano Albo et autres

it (code pays fourni par la source)

Signalling Pathways and Cellular Effects Activated in Endothelial Cells by Exogenous AIMP1

Valentina Charlotte Jackson, Sylvia Dewilde, Alessandra Giuliano Albo, Davide Corpillo et autres

it (code pays fourni par la source)

Role of a 23 bp Insertion in Exon 3 of the Endothelial Cell Protein C Receptor Gene in Venous Thrombophilia

Mario Von Depka Prondzinski, Andreas Czwalinna, Roswit Eisert, Cornelia Wermes et autres

de (code pays fourni par la source)

Analysis of the Fibrinogen Genes of 40 Patients with Suspicion of Dys-, Hypo- or Afibrinogenemia

Andreas Czwalinna, N. Bartkowiak, Barbara Canepa, Arnold Ganser et autres