Shaunak Ghosh

A centrally positioned cluster of multiple centrioles in antigen-presenting cells fosters T cell activation

Isabel Stötzel, Ann-Kathrin Weier, Apurba Sarkar, Subhendu Som et autres

Cellular polarization plays a crucial role in regulating immunological processes and is often associated with reorientation of the centrosome. During immune synapse formation, centrosome repositioning in lymphocytes assists in T cell activation. While a single centrosome, consisting of two centrioles, is present …

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Glucose tasting depletes intracellular calcium stores and impairs macrophage functionality

Laura Schlautmann, Daniel Burgdorf, Shaunak Ghosh, Alina Schieren et autres

signaling and homeostasis and demonstrate a regulatory role of taste receptors in macrophages, enhancing our understanding of immune cell dysfunction in diabetes.

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Protecting centrosomes from fracturing enables efficient cell navigation

Madeleine T. Schmitt, Janina Kroll, Mauricio J. A. Ruiz‐Fernandez, Robert Hauschild et autres

The centrosome is a microtubule orchestrator, nucleating and anchoring microtubules that grow radially and exert forces on cargos. At the same time, mechanical stresses from the microenvironment and cellular shape changes compress and bend microtubules. Yet, centrosomes are membraneless organelles, raising the …

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LSPR‐Based Biosensing Enables the Detection of Antimicrobial Resistance Genes

Stephan Kastner, Anne‐Kathrin Dietel, Florian Seier, Shaunak Ghosh et autres

The development of rapid, simple, and accurate bioassays for the detection of nucleic acids has received increasing demand in recent years. Here, localized surface plasmon resonance (LSPR) spectroscopy for the detection of an antimicrobial resistance gene, sulfhydryl variable β-lactamase (blaSHV), which confers …

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Immunomodulatory and antimicrobial non-mulberry Antheraea mylitta silk fibroin accelerates in vitro fibroblast repair and regeneration by protecting oxidative stress

Sohini Sen, Shaunak Ghosh, Sayantan De, Piyali Basak et autres

Initially SF accelerated pro-inflammatory cytokines, restricted anti-inflammatory cytokines; later it regulated in reverse order. SF potentially eradicated ROS and promoted Ki-67 cellular regeneration whereas pristine PU could not.

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Fine nanostructural variation in the wing pattern of a moth Chiasmia eleonora Cramer (1780)

Shaunak Ghosh, Monalisa Mishra

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