Simona Brogneri

Segmental analysis of left atrial substrate severity predictors in patients undergoing persistent atrial fibrillation ablation

Edoardo Cecchini, Gennaro Fabiano, P Liporace, Paolo Sorrenti et autres

Introduction Outcomes after catheter ablation remain suboptimal in persistent atrial fibrillation (AF), likely reflecting a more pronounced left atrial (LA) structural and electrical remodeling in these patients. Empirical additional ablation lesions lack robust supporting evidence and may even lead to adverse outcomes, …

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Correlation between frailty status, surgical access, and outcomes in older adults with valvular heart disease undergoing cardiac surgery

Paolo Cimaglia, Elisa Mikus, Michele Trichilo, Elisabetta Tonet et autres

Frailty is not routinely assessed nor incorporated into the Euroscore II, and evidence on minimally invasive cardiac surgery (MICS) in older frail adults remains limited. We evaluated whether frailty assessment improves the prognostic performance of the Euroscore II and whether MICS provides …

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Low Arrhythmic Risk in Individuals With Brugada ECG Pattern and a Negative dST-Tiso Criterion

Saverio Iacopino, Paolo Sorrenti, Gennaro Fabiano, Giuseppe Campagna et autres

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Hybrid mini-thoracotomy for Brugada syndrome: epicardial substrate characterization and ablation—results from UNCOVER(BrS) study

Saverio Iacopino, Paolo Sorrenti, Andrea Petretta, Jacopo Colella et autres

Background: Data on the safety and efficacy of thoracotomy epicardial ablation for Brugada syndrome (BrS) are limited. The ongoing UNCOVER(BrS) trial aims to evaluate epicardial substrate homogenization in patients with symptomatic BrS. Objective: To report the study design and preliminary outcomes of …

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High-Sensitivity Cardiac Troponin Predicts Major Cardiovascular Events in Diabetic Patients With Critical Limb Ischemia and Foot Lesions

Paolo Cimaglia, Luca Dalla Paola, Anna Carone, Giuseppe Scavone et autres

Background: Diabetic patients with critical limb ischemia (CLI) and foot lesions show a poor prognosis. Optimal risk stratification to guide tailored intervention is still uncertain. The aim of the present study was to assess the prognostic role of high-sensitivity cardiac troponin T …

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Performance of Synthetic Extracellular Volume Fraction in Different Cardiac Phenotypes From a Prospective Cohort of Patients Referred for Cardiac Magnetic Resonance

Stefano Censi, Paolo Cimaglia, Alessandra Barbieri, Monica Naldi et autres

BACKGROUND: A synthetic myocardial extracellular volume fraction (sECV) can be obtained without blood hematocrit (Hct) by using the linear relationship between Hct and the longitudinal relaxation time of blood. Concerns have been raised about the widespread clinical application of this approach. PURPOSE: …

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PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes

Rosellina Margherita Mancina, Rocco Spagnuolo, M. Milano, Simona Brogneri et autres

BACKGROUND: Inflammatory bowel diseases (IBD) are characterized by chronic relapsing inflammation of the gastrointestinal tract and encompass Crohn's disease and ulcerative colitis. IBD are often associated with extraintestinal manifestations affecting multiple organs including the liver. Increased levels of serum aminotransferases, possibly related …

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The link between nutritional parameters and bone mineral density in women: results of a screening programme for osteoporosis

Theodora Lamprinoudi, Elisa Mazza, Yvelise Ferro, Simona Brogneri et autres

BACKGROUND: A positive association between handgrip strength and bone mineral density was demonstrated, but not all the investigations confirmed these results. We conducted a screening programme for osteoporosis in a large cohort of postmenopausal women to investigate the relationship between handgrip strength, …

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